Infertility

Talk to me about OHSS

Hi. I normally post on 3 TTC, but I wanted to ask this question here since you ladies have seen it all.
I am currently on CD 12 of my 1st IUI cycle. I had my U/S today, my lining looks good and I produced 9 follicles (4 on the R, 5 on the L). This was on 100mg of Clomid. Smallest was close to 14, biggest was 17. Average size was about 15-16. I'm pretty sure my IUI will be cancelled, but what I'm really afraid of is OHSS if by some sort of miracle I get pregnant. What are the chances of getting OHSS?
*Losses mentioned*
Me: 34 DH:32
TTC #1 since Dec 2011
HSG = tubes clear, bicornuate or septate ute; MRI= severe arcuate uterus no septum seen 
SA #1 low count, low morph;  SA#2 4% Morph, count OK  SA#3 july 2014= NORMAL!!!
9/2013  IUI#1 w/Clomid 100mg = over response; cycle converted to cryoocyte IVF
IVF #1: 9/15 ER= 9 mature eggs, all eggs made it thru vitrification
10/23 ICSI 6 fertilized; 10/28 5dt of two morulas. Hold on to me babies, stick, stick, stick!!
11/6 BFP EDD 7/14/14 Beta #1= 18; 11/9 Beta #2= 44.8; 11/12 Beta #3= 7 = Early loss @4w6d. No frosties
Feb 2014 Hysterscopy = no septum seen ute all clear in the inside
 IUI #1.1 4/2/14 Beta on 4/16 BFN
Thinking about IUI #2  RE advised to try 3?????
Natural cycle surprise BFP 8/3/14 EDD 4/11/15  beta#1(8/5/14)=35 Beta#2(8/8/14)=22  CP/Early loss@5w
PAIF/SAIF Welcome
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Re: Talk to me about OHSS

  • I had 14 follicles around 16-22 when I did ivf and I didn't get ohss. My RE said ohss usually happens when people produce like 20+ follicles. I think you should be fine but everyone is different.
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  • Oh man! Thanks that is such a relief to hear.
    *Losses mentioned*
    Me: 34 DH:32
    TTC #1 since Dec 2011
    HSG = tubes clear, bicornuate or septate ute; MRI= severe arcuate uterus no septum seen 
    SA #1 low count, low morph;  SA#2 4% Morph, count OK  SA#3 july 2014= NORMAL!!!
    9/2013  IUI#1 w/Clomid 100mg = over response; cycle converted to cryoocyte IVF
    IVF #1: 9/15 ER= 9 mature eggs, all eggs made it thru vitrification
    10/23 ICSI 6 fertilized; 10/28 5dt of two morulas. Hold on to me babies, stick, stick, stick!!
    11/6 BFP EDD 7/14/14 Beta #1= 18; 11/9 Beta #2= 44.8; 11/12 Beta #3= 7 = Early loss @4w6d. No frosties
    Feb 2014 Hysterscopy = no septum seen ute all clear in the inside
     IUI #1.1 4/2/14 Beta on 4/16 BFN
    Thinking about IUI #2  RE advised to try 3?????
    Natural cycle surprise BFP 8/3/14 EDD 4/11/15  beta#1(8/5/14)=35 Beta#2(8/8/14)=22  CP/Early loss@5w
    PAIF/SAIF Welcome
    Image and video hosting by TinyPicImage and video hosting by TinyPic





  • I actually currently have OHSS and let me tell you it's completely miserable.  However, I didn't get it from IUI meds....I got it after my ER for my current IVF cycle.  My trigger was Lupron and HCG, and I had over 50 follices and 31 eggs.  They expected it with me.  Did you doctor say that you're at high risk of getting it?  My doctor basically told me I was more than likely going to get it, so that's why we froze all of our embryos and will do FET. 
    Me 31 ~ DH 30
    IVF/FET #1 - BFP!!
    <3 CJW 6/15/2014 <3
    DX - PCOS 2004
    FET #2 - scheduled for 11/24/15
  • I agree with the ladies above, I don't think you have anything to worry about.  I had about 9-10 follicles before my 3rd IUI and no OHSS, but for IVF, I had 37 eggs and got OHSS.  I know everyone is different, but I don't think you should sorry much.  Good luck!

    **Sig warning***

     

     

    TTC since 9/2011. DH - 32, me 32.

    IUI#1 (natural): BFN; IUI#2 (clomid): BFN; IUI#3 (clomid and follistim): BFN.

    IVF #1 March 2013, freeze all (OHSS).

    FET#1 June: BFN

    FET#2 August: delayed due to thin lining (6.3).  Took a few months off to try and thicken the lining with lots of estrodial.  FET#2.2 December: Cancelled due to thin lining (4.8). Two frosties left.

    *New RE* Sonohystrogram and hystereoscopy done in Feb.

    IVF #2: ER 3/4/14  ET 3/7/14, transferred 3, 3 day 9 cell perfect embryos.  No frosties.

    Beta #1 (14dp3dt) 504

    Beta #2 (21dp3dt) 11,561

    First ultrasound on 4/3/14 showed 3 sacs: one empty and two with beating hearts!!  At 7w2d, found out that one baby did not have a heartbeat anymore.  Praying that baby B makes it.  Baby B is a girl!

    EDD 11/25/14 BORN 11/29/14

    **PAIF/anyone welcomed to comment!!  Thank you.


     imageimageimageimage

     

  • Thank you for all your responses. My RE called me yesterday afternoon to discuss this unexpected scenario and after brainstorming he was able to offer me an option that would suit me and them. We are converting this cycle to a cryoocyte IVF.  Its basically IVF only they will freeze my eggs and them thaw them out. 

    Why are they freezing them?, you may ask. Well the label on oocyte cryopreservation as an experimental treatment was just recently removed and in order for my RE office to be able to offer this service they need more experience and well more test subjects. So what they offered me is if I agree to the cryoocyte IVF they will just charge the same as we would have paid on the Clomid IUI cycle. Needless to say we agree as the other option was getting benched. 

    Today got my follow up U/S follies looking great and growing! Next step is the ER on Sunday.
    I am very excited about everything, it is very unexpected as we were prepping for IUI and ended in IVF, but sometimes things work out for the best. 
    *Losses mentioned*
    Me: 34 DH:32
    TTC #1 since Dec 2011
    HSG = tubes clear, bicornuate or septate ute; MRI= severe arcuate uterus no septum seen 
    SA #1 low count, low morph;  SA#2 4% Morph, count OK  SA#3 july 2014= NORMAL!!!
    9/2013  IUI#1 w/Clomid 100mg = over response; cycle converted to cryoocyte IVF
    IVF #1: 9/15 ER= 9 mature eggs, all eggs made it thru vitrification
    10/23 ICSI 6 fertilized; 10/28 5dt of two morulas. Hold on to me babies, stick, stick, stick!!
    11/6 BFP EDD 7/14/14 Beta #1= 18; 11/9 Beta #2= 44.8; 11/12 Beta #3= 7 = Early loss @4w6d. No frosties
    Feb 2014 Hysterscopy = no septum seen ute all clear in the inside
     IUI #1.1 4/2/14 Beta on 4/16 BFN
    Thinking about IUI #2  RE advised to try 3?????
    Natural cycle surprise BFP 8/3/14 EDD 4/11/15  beta#1(8/5/14)=35 Beta#2(8/8/14)=22  CP/Early loss@5w
    PAIF/SAIF Welcome
    Image and video hosting by TinyPicImage and video hosting by TinyPic





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