I have the beta-3 integrin biopsy scheduled for next week and I always talk myself into getting freaked out about these things! I've had everything done, including hsg, saline sonography, hysteroscopy, Doppler u/s, etc. but this one sounds painful! And did your regular OB do it? Mine sounded unsure if she would be able to do it for me (ccrm said anyone should be able to do it, including nurse practitioners) so I was a little concerned about that too..
While we are on the pain subject, did anyone have a mammogram? How bad is it? Mines tomorrow.
One more question... Any ideas on getting my siggy to update? I've tried about a dozen times and it never changes..it's been about a month..
TIA!
Me: 37, DH: 38: ttc 7 years, dx: unknown 10/11: after 2 years, saw a RE, FSH 5.4 11/11: BFP! (surprise after thyroid & normal hsg), 12/11: missed m/c after 7 week u/s, 1/12: D&C 6/12 IUI#1-IUI #3: clomid = BFP!, C/P IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN. IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN. IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal.
Looking into options of DE, Fresh vs frozen. 10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015. Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue!
Please send any positive thoughts our way! EDD:8/24/2015
Baby Will born 8/18. He's perfect.
I worked myself up about it too but it turned out to be ok. My RE actually did mine himself (which may be why it didn’t really hurt). I was told to have a full bladder and take two Advil an hour before. I hope you experience is the same as mine!
I have had two mammograms and I would say in my experience mammograms are worse than the E-tegrity test! ...But I am a 34DD so there is a lot of squishing going on with me!
Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011 1 Clomid/Ovidrel BFN May 2011 Natural cycle Aug 2011 BFP M/C 4 Weeks 1 IUI Sept 2011 BFP M/c 7 weeks Provera Dec 2011 BFP M/C 3 Weeks
DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011 IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone) IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone) Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) Went to Beer Center- high tnf, low lad, implantation failure
Nov/Dec 2012 LIT Treatment
Dec 12 Humira Jan 2013 BFP Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin Miracle Born August 2013 Premature
***sig***
My biopsy was done by my RE and no big deal at all. It was much easier than the hsg and saline sono. It lasted only a few seconds. I second the need for a pad and Tylenol beforehand would probably help. Good luck!
I've had the biopsy/scratch 3 times. I have to say it my least favorite test/procedure that I've been through. It's very short, only like 30-60 sec but I found it painful and highly uncomfortable every time. Take some Tylenol. I didn't bleed afterwards.
My RE did it but was a bit of a dope about reading the instructions well, so I (after reading them a number of times) had to tell her what to do. Advice: read the instructions and understand them.
My mammer-jammer wasn't painful just sort of strange feeling. I have C cups.
Hope that helps.
BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/??? MFI issues
Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013
Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked,
2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal
Moving on to IVF.
IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy
Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14
After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14 We are so in love with her.
"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."
I had the endometrial scratch/biopsy done. I took tylenol or advil before it. It definitely hurt but it was over in less than a minute. My RE did it. They do a scratch in all for quadrants and it's as fast as 1- 2 - 3 - 4. RE counted for me and then was done. I didn't bleed too much after but I have had some spotting during the first tri when may have been a little from this. GL!
< Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006) April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response cycle 2: June 2012, femara 5mg; cycle cancelled, no response cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4) Repeat MRI July 25,2012- Cyst unchanged, likely old infarction. Aug. 8: met with RE, move to injectables if HSG and SA normal Aug. 23: HSG all clear; DH- perfect Switched to a new RE in early Sept. IVF here we come Genetic testing reveals: Fragile X- Intermediate risk/grey zone. IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS. IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 , beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.
FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks. 8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.
I also had the scratch before this last FET and the actual procedure was not painful but had alot of cramping on the day of after and then the bleeding began!! For like a week and one of the worst periods I ever had!! I chalked it up to hoping It would be my last period for at least 9 months so I dealt with it!
Me 34 and DH 39 married in aug. 2002
Did 5 round of clomid 2010 =BFN
High levels of NK CELLS DX sept.2012 DOR:# 0.02
IVF #1 May 2012 ER 4, EF 2, ET 2 =BFN
MINI IVF Oct.2012 Cancelled 10-27-12
Ivf #3 Antagonist Protocol April 2013
Shared cycle..Donor cycled in July Got 12 eggs 9 fertilized and 8 frozen!!
DE FET #1 Sept. 3rd 2013 FIRST BFP EVER 5dp5dt
miscarried Sept 24th at 5 weeks 5 days
Etopic D&C and hysterscopy Nov 5 2013
dx with pre genetic blood clotting dec 2013
FET #2 Jan 31st 2014
Miscarried for a second time again at 5 weeks 5 days
Currently fostering to adopt an amazing little 1 year old boy..P.J!
I had the endometrial biopsy twice. Once by a nurse practitioner and it was pretty dang sucky and once by my RE and while it hurt a lot, it's literally over in less than 30 seconds. I didn't bleed too badly.
Mammogram was not a big deal, just uncomfortable. I've had 2.
Me-42 DH-43 TTC #1 since 3/11
HSG 7/11 showed possible blockage
8/11 BFP, then early m/c (Natural)
9/11 blood tests reveal Factor V Leiden (heterozygous)
11/11 Hysteroscopy revealed uterine septum, which was repaired
12/11 1st round of Clomid (100mg)=BFN
1/12 2nd round of Clomid (100mg)=BFN
2/12 Repeat HSG=All clear
2/12 IUI with injectables #1=BFN
3/12 natural cycle=BFN
4/12 IUI with injectables #2=C/P
7/12 IVF #1=30ER, 9F, 3T, 1 Frostie
7/29=BFP!
8/27/12 No Heartbeat. Waiting to M/C
9/13/12 D+C
12/12 Operative Hysteroscopy
1/31/12 IVF#2 ...BFP
2/6 m/c
2/12 methotrexate due to presumed ectopic
Re: Tell me about endometrial biopsies please
I worked myself up about it too but it turned out to be ok. My RE actually did mine himself (which may be why it didn’t really hurt). I was told to have a full bladder and take two Advil an hour before. I hope you experience is the same as mine!
I have had two mammograms and I would say in my experience mammograms are worse than the E-tegrity test! ...But I am a 34DD so there is a lot of squishing going on with me!
Here is the link to change your siggy https://forums.thebump.com/profile/signature
***SIGNATURE WARNING***
TTC #1
Me 42, DH 47
Dx = AMA/DOR, MFI
IVF/ICSI #1 = BFN
IVF/ICSI #2 = BFP; early loss
IVF/ICSI #3 (DE) = BFP; early loss
FET = BFN
IVF/ICSI #4 (DE w/ CCS) = BFP
Beta #1 @ 10dp6dt = 265; Beta #2 @ 14dp6dt = 1251.
1st U/S @ 6w2d showed one perfect little heartbeat!
2nd U/S @ 7w2d. HB 132 & everything measuring on track.
Our beautiful little girl arrived January 2015!
I had it done by my RE as well and it's not too bad. Take some advil and a big breath. You'll do great. It's like a quick pinch.
No mammograms for me, sorry. But Good Luck!
me 33/DH 36
ttc since 10/2008; d/x: mild MFI, stageII endo
~~PAIF/SAIF Welcome~~
11 IUI’s = 1 m/c (7w4d)
IVF#1 January 2012 BFN, FET #1 April 2012 BFN
Surprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)
IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762
U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160
Stick Frogger Stick! Please!!!!!!!!!!!!! It's a Girl, EDD April 7, 2014
The biopsy took 2 mins and hurt a lot but the nurse held my hand and that helped alot. Wear a pad I bled a lot after. My regular OB did it.
Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
1 Clomid/Ovidrel BFN May 2011
Natural cycle Aug 2011 BFP M/C 4 Weeks
1 IUI Sept 2011 BFP M/c 7 weeks
Provera Dec 2011 BFP M/C 3 Weeks
IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone)
Went to Beer Center- high tnf, low lad, implantation failure
Jan 2013 BFP
Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
Miracle Born August 2013 Premature
Yours doesn't have to be a sad story
Age: 35 TTC since 2005, MFI & DOR
IVF #1 Sep '11 - canceled poor response
IVF #2 Nov '11 8R/8M/4F 3dt x2 - chemical
IVF #3 April '12 11R/6M/4F 3dt x2 - m/c
FET #1 Aug 2012 3dt x2 - BFN
**new RE**
IVF #4 Jan '13 BFN 11R/6M/6F 5dt x2 - BFN
IVF #5 July '13 16R/10M/10F 5dt x2 + 1 frostie
9dp5dt Beta 1 = 344!! 16dp5dt. Beta 2 = 4822 7wk u/s= 2 heartbeats!
Twin girls! 3/6/14
TTC #1 since 1/10
DX: Unexplained/??? MFI issues
Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2013
4w c/p loss 10/29/12 - EDD July 2013
Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal
Moving on to IVF.
IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy
Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14
After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
We are so in love with her.
"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."
Everybody is welcome!!!
<
Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
cycle 2: June 2012, femara 5mg; cycle cancelled, no response
cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
Aug. 8: met with RE, move to injectables if HSG and SA normal
Aug. 23: HSG all clear; DH- perfect
Switched to a new RE in early Sept. IVF here we come
Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 , beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.
FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks. 8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.
12/1: met with RE to discuss trying for #2