I am a 32 y/o husband and my wife and i are trying to have our first child. She is on her first round of Letrozole IUI and she has become very moody and not her self at all. She has been on Clomid before and she was the same way. I am not really sure how to handle her mood swings and outbusrts. Any advice from a womans ponit of view?? How has your husband handled this? Thanks!