Infertility

IVF #2 w/ New Protocol

Hey everyone,
Not sure who all remembers me but I'm on day 7 of stims for IVF #2. With IVF #1, I stimmed for 8 days with GonalF, low dose hcg and ganirelix added at the end. I had a few follies that grew super quick and a bunch much farther behind. Of the 12 eggs retrieved, only six were mature.
Our RE decided for this round to do the Lupron for 2 weeks and then added the GonalF and low dose hcg in hopes the Lupron would keep all the follies growing at a similar rate.
We had our day 7 appt this am and they saw only 2 big (17s) on the right and 7 smaller ones (ranged from 7-13) on the left. My e2 was 735. I'm to go back in Wednesday.
At this point I'm just frustrated because I feel like this is no different than last time. Our embryos had a high attrition rate on the back end last time (they think due to sperm issues) so the goal this time was not to have more eggs but have more of them mature. And I feel like its not working! Anyone else having/had similar problem?
Sorry this is so long!!
Me-31/DH-32, TTC since Aug 2011, HSG/Blood work all normal 3 SAs - results all over the place. DX Unexplained 
3 failed IUIs, IVF #1: 12R/6M/6F, transferred 1 5d blast, no frosties, bfn.   IVF #2:  12R/6M/5F, transferred 1 5dt, 2 frosties, bfn.    Yale EFT test done, mild inflamation - maybe endometrisis?   FET #1: transferred 2 6d blasts, BFP!!!  Beta #1: 606 e2:303, P: 47   Beta #2: 1,817    Beta #3: 8,625




Re: IVF #2 w/ New Protocol

  • Welcome back Clynn!
    I'm sorry your follies aren't cooperating with you again! That must be so frustrating! I hope that things start looking up on Wednesday.
    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • Hi there!
    I'm sorry things arent going how you had hoped they would.  I hope that things turn around for you on Wednesday :)
    CafeMom Tickers
     Anniversary
    TTC since July 2011
    BFP #1: 2/15/12-Ectopic/Mtx at 6 wks

    BFP #2: 10/12/12-m/c at 5 wks. 
    BFP #3: 8/27/13
    Me: MTHFR, Low AMH (1.1), High NK cells and Antiphospholipid Antibodies.
    DH:MFI-Low morph (1%), DNA fragmentation: Excellent!
    5 rounds of clomid, 3 IUIs, and multiple non-medicated cycles- BFFN                                                      
    IVF with ICSI in August 2013 brought us our babies.  ER-9R, 7M, 4F w/ICSI  ET of 2-Grade 2 blasts. 
    + HPT at 6dp5dt. #1 (8dp5dt)- 105    #2 (13dp5dt)- 510  #3 (15dp5dt)- 960  #4 (17dp5dt)- 1889
    Dx shortened cervix, PTL, and preeclampsia during pregnancy.  Lots of medications and 13 weeks of bedrest, babies were born healthy at 34w4d!


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  • Hi! I hope things start to look up at your next appointment. I'm sorry things aren't going as planned. It can be so flipping frustrating.

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     ttc #2 since 2004 Me (35): Stage 3 Endo, DH (34): High DNA Frag

    IVF/ICSI #2: April 2014: BFP!!!!!!

    ET of 2 great quality embryos. + BFP on 9dp5dt. Beta #1 (10dp5dt): 257, Beta #2 (14dp5dt): 1561,

    Beta #3 (21dp5d5): 8,172. Wow. It seems this is actually working. Shocked beyond belief.

    1st u/s @6w5d: Baby A hb 124, Baby B hb 127 (Both measuring perfectly!)

    Lost baby A. Praying that baby B stays healthy. Baby B hb 175 at 11 weeks

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  • Hi there, Clynn! I remember you, and I'm sorry to hear that you have to be back here, but I'm glad you are on the path again. For me, IVF 2 had much better maturity (see siggy) and the LH in the menopur made the difference. What's your protocol?
    | Married since 2008 | DH and I: Both 30 | Me: Endometriosis and Carrier of an X-Linked Dominant Genetic Disorder | DH: Low Morph | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 5AA frozen blasts. Freeze-All IVF#2: May 2013 ER 5/15. 31R, 21M, 20F. 6 5AA frozen blasts. Our PGD probe was completed in late June (total of 20 weeks to develop). PGD and PGS Results came on 6/19: 3 healthy embryos (normal chromosomes and unaffected by my family's genetic disorder). FET #1: July 2013 Natural Cycle - Cancelled due to insufficient lining (only got to 7.5mm). FET #1.2: August 2013 - Medicated Cycle with Lupron & Estrogen Patches to build up lining. Single embryo transfer was 8/23. Beta #1: 240! Beta #2: 578! U/S on 9/19 at 6w4d: We saw the heart beating at 131bpm. Second U/S on 10/4 at 8w5d: We saw the heart beating at 178bpm. EDD 5/11/2014
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  • Not sure the exact name but I was in BCP for over a month and then started a Lupron 2-week kit. I started GonalF (150 units) and low dose HGC (10 units) after 14 days in the morning and GonalF (150 units) and Lupron (5 units) in the pm.
    Me-31/DH-32, TTC since Aug 2011, HSG/Blood work all normal 3 SAs - results all over the place. DX Unexplained 
    3 failed IUIs, IVF #1: 12R/6M/6F, transferred 1 5d blast, no frosties, bfn.   IVF #2:  12R/6M/5F, transferred 1 5dt, 2 frosties, bfn.    Yale EFT test done, mild inflamation - maybe endometrisis?   FET #1: transferred 2 6d blasts, BFP!!!  Beta #1: 606 e2:303, P: 47   Beta #2: 1,817    Beta #3: 8,625




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