Success after IF

Q for ladies who have done IVF

Did the injects make you crazy/emotional or hypersensitive? In thinking about doing ivf, one thing I am worried about is how I will react and feel. I was a raging, irrational B on clomid so I am worried that high dose stims will be worse. I still have to go to work if I do this and not go Harry Kerry on someone
IF DX: DOR & Fragile X pre-mutation carrier
2011: FSH 13.3 & E 99; AMH 0.54 2nd FSH 6.2 E 40's AFC: 8
BFP from Clomid/IUI ~ Pre-e and IUGR during pregnancy ~ DS born 9/4/12
Feb./March 2013: AMH less than 0.16 (undectable) and AFC = 4;
BFP from supps ~ DS#2 due May 2014

May 2014 January Siggy Challenge:
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Re: Q for ladies who have done IVF

  • I just completed my second round of IVF. This round they put my body in a state of menopause then I started injections to build up my estrogen again. The only side effect I had was a horrible headache because of estrogen deprivation. If you are getting the injections that is shutting your hormones down you will get a headache. Other than that I felt normal.
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  • Yes. My fresh IVF cycle made me really crazy, however I was also dealing with some really awful work related issues and my DH was having healtg issues at the same time so it's hard to know how much to blame on the meds.
    IVF, acupuncture, meditation and a miracle. 

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     Our sweet Valentine's Day FET.

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  • During Lupron, I started having major anxiety issues (chest pain, racing heart, irrational fears) due to the estrogen suppression. Once it got back up, I felt fine again. The RE said it was a nice glimpse into menopause- super. During stims, the discomfort from swelling ovaries was a much bigger deal. Between trigger and ER, I could hardly sit still. I did have some flu like symptoms from Menopur, but never experienced any emotional s/e from Follistim. Although, I never had issues on Clomid, so I'm not sure if that makes a difference.
    TTC in 2009, Dx: Unexplained IF
    Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
    12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
    Our perfect baby boys were born at 36w1d!! 








  • I feel like I worse on clomid than my IVF cycle. I was more easily irritated during stims but I've also got a husband that loves to irritate me (thanks FIL for teaching him that). I am a teacher and did it in the summer so I didn't have work stress to add to it though.

     imagePhotobucket

    TTC #1 since 3/2011
    DX: anovulatory and severe MFI
    DH is a testicular cancer survivor
    IVF#1 w/ICSI lupron, gonal f, ovidrel
    ER 6/15/12 6R 6M 6F! ET 6/20/12
    Beta #1: 154 Beta #2: 509 Beta #3: 7326
    Baby Boy born 3/1/2013
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    TTC#2: 6/2014 all testing came back normal

    IVF#2 (#1 for LO#2) 9/2014 - 17R 10M 10F 4 blasts frozen on day 6.

    FET #1 10/15/14 - Beta #1: 216  Beta #2: 823


    Baby Boy born 7/10/2015


  • I think it is different for everyone. For me, the only drug that affected me was Lupron. It was bad though. It made me feel almost buzzed when I was on the full dose. Once I started stims and decreased my Lupron dose it stopped bothering me. I was teaching fourth grade during both my IVF cycles and was fine at work.
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    Unexplained Infertility

    After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!

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    TTC #2
    After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!

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    Surprise! Baby #4 is due in March!
  • I had some slight moodiness and stuff but nothing I couldn't handle. DH said I was pretty good too. I would say though that if you had some issues with clomid you're probably more likely to also have them with the IVF drugs. Your RE will monitor you closely though!
    MF (low motility) - Began stims for IVF#1 7/21/12
    ER 8/2/12 - 14 eggs retrieved, 12 mature and ICSI'd, 6 fertilized. ET 8/7 - 2 embies. Beta#1 8/17: 143! Beta#2 8/20: 590! Beta#3 8/22: 1,162! 1st US 9/4: one beautiful little bean with the best sounding HB I've ever heard!
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  • I agree that it's different for everyone.  I had some moodiness too, but nothing crazy.  I was worried since I'm a teacher and absolutely cannot lose it on my students... but I was fine.  Good luck with your decision!
      image

    TTC starting November 2010  HSG clear, DH SA #1- Slightly low count & motility SA#2-normal
    Lap&Dye/Hysterscopy Feb 2012: Endo stage 2
    April - June 2012: Femera 5 mg & 3 IUIs = All BFN    July/August 2012: IVF #1 = C/P
    September/October 2012: IVF #2 BFP! Beta 1= 223 Beta 2 = 480 Beta 3 = 11,440
    My beautiful daughter was born June 21, 2013
    TTC #2 naturally, no luck
    IVF #3 April 2015: BFN
    IVF #4 July 2015: BFP! Beta 1 9dp5dt = 409, Beta 2 13dp5dt = 1743


  • It's hard for me to separate the emotions due to meds versus emotions from the stress of the cycle. In general, Ive managed two max dose cycles with minimal outbursts at home or work. Was it stressful and emotional? Yes. Was it manageable? Yes. Good luck!
    DX: Severe MFI 
    IVF # 1 ~ Antagonist ~ ER 1/27/11~ ET 1/30/11 ~ + HPT 7dp3dt 
    DD born med-free on 10/24/11 
    Lilypie - (lZjk)
    IVF # 2 ~Antagonist ~ ER 6/5/13 ~ ET 6/10/13 ~ + HPT 4dp5dt 
    Lilypie - (OUlo)

  • I didn't notice much when I was on Bravelle, but WOW did I notice a difference my second cycle on Gonal F! It seemed like my emotions were all intensified and I had a few freak outs, but I managed to keep it together at work. However, everybody reacts to the drugs differently and there is no way to tell how you will respond until you're in the moment. Thank goodness for PTO, LOL! Good luck!
    Me: 30, DH: 30
    ~*~Married 8/31/08~*~

    DX: MFI due to Chemo/Stem Cell Transplant for Hodgkin’s Lymphoma. RE said IVF is best option with DH's frozen boys.
    IVF #1 April 2012: Menopur and Bravelle; 1 egg retrieved, 0 fertilized. Boo.
    IVF #2 August 2012: Gonal-F 300, Menopur 300. Beta #1 9/6: 382... BFPx2!

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    Our boys couldn't wait to meet us! Colin and Kieran arrived March 26, 2013 at 33w1d.

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  • I went through three IVF cycles, one cancelled right before retrieval, and I can honestly say the side effects from meds was not too bad. Lupron made me very tired but stims didn't really change anything. I did one clomid cycle way back when and I was a horrid, raging, sobbing, cray cray biatch! I think dh was ready to move out until it was over, lol!
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    TTC# 1 since 5/10
    Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
    DX: Unexplained IF
    Many IUI's with various meds all BFFN
    IVF #1 11/11 canceled due to OHSS
    IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
    IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
    Healthy baby girl born at 36w4d on 3/9/13

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    TTC #2
    IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
    Beta 6/18 BFFN

    FET of 2 blasts 7/24...BFP!
    Healthy baby girl born at 36w3d on 3/17/15

    TTC#3
    IVF #5 June 2018- PGS planned, no surviving embryos
    IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
    IVF #7 August 2019-....?
  • Thanks for sharing your experiences. Dh said if it was anything like clonid, he was going to take DS and move out for the cycle.
    IF DX: DOR & Fragile X pre-mutation carrier
    2011: FSH 13.3 & E 99; AMH 0.54 2nd FSH 6.2 E 40's AFC: 8
    BFP from Clomid/IUI ~ Pre-e and IUGR during pregnancy ~ DS born 9/4/12
    Feb./March 2013: AMH less than 0.16 (undectable) and AFC = 4;
    BFP from supps ~ DS#2 due May 2014

    May 2014 January Siggy Challenge:
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  • I just completed my second round of IVF. This round they put my body in a state of menopause then I started injections to build up my estrogen again. The only side effect I had was a horrible headache because of estrogen deprivation. If you are getting the injections that is shutting your hormones down you will get a headache. Other than that I felt normal.

    This exactly!!

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    IVF/ICSI #1 July/August 2011 BFP # 1 - B/G twins - preterm labor/cervical incompetency @ 23w3d FET # 1 March/April 2012 - BFN 5/1/12 FET # 2 July 2012 - BFN 7/24 FET # 3 BFP! EDD 5/15/13 Lilypie Angel and Memorial tickers Lilypie Angel and Memorial tickers Pregnancy Ticker
  • I think I was pretty normal on my meds during my IVF cycle.  I did have one "fit" because my DH was picking out yogurt flavors I didn't like....but then we laughed about it.  Only side effect I have now is slight OHSS....but it's not too terrible.  GL to you!

    Me:34  DH: 29

    Married: 7/10/10

    TTC since April 2011

    Many failed IUIs with clomid, femara, and ovidrel

    IVF #1 July 2013 with Menopur, Bravelle, Ganirelix, HCG trigger, Progesterone

    Beta 1(8/1): 401, Beta 2(8/5): 1822  1st U/S: 8/13: 2 sacs!!!  2nd U/S: 8/20: 2 healthy heartbeats!!

     

     

     

  • I did have hormonal mood swings on my IVF meds, but I can't say they were any worse than when I was strictly on BCPs to start my cycles. I don't recall Clomid giving me any mood swings though, so like PP said, maybe if you are sensitive to Clomid you will be more sensitive to stims. 
    dx: MFI 0% morph & low count. Occasional Anovulatory cycles.

    TTC #1
    • IVF #1 4/21/12 - c/p
    • IVF#2 8/1/12 - BFP! DD arrived 4/10/2013.

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    TTC #2
    • FET #1 3/18/14 - BFP! DS arrived 11/19/2014.

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  • ccamccam member
    Clomid was awful for me. I would much rather do something like follistim. On a regular IUI cycle with follistim, I was fine. During IVF, the only real side effect was that I felt like my ovaries were the size of beach balls.

    ___________________________________________________________________________

    Trying for #1 since May 2010   l   DX ~ Unexplained Infertility June 2011

    IUI #1&2 = BFN; IUI #3 = BFP, m/c @ 6 weeks

    November '11 ~ IVF#1 ~ ER 11/18 (29R, 17F) ~ 5dt of one beautiful blast on 11/23 = BFP!!

    Beta #1 9dp5dt = 116, P4 = 28 ~ Beta #2 13dp5dt = 700 ~ Beta #3 20dp5dt = 9500, P4 = 26

    1st u/s 12/27 - hb of 156!! EDD 8.10.12 :)   **TEAM GREEN!**

    Sweet baby boy born 8.18.12

    Baby Birthday Ticker Ticker

    Trying for #2

    FET #1 - October '13 - c/p   l   FET #2 - December '13 - cancelled :(   l   FET #2.2 - 1.30.14 - BFN

    ~ More testing - hysteroscopy, endometrial biopsy & more b/w - all normal / negative~

    Surprise BFP while waiting on FET #3 ~ beta #1 500; beta #2 1600; first u/s 4/3 - measuring 5w5d, no hb yet!; 2nd u/s 4/10 - hb 132, measuring 6w6d - EDD 11.29.14 :)    **TEAM GREEN!**

    Beautiful baby girl born 11.24.14

      Baby Birthday Ticker Ticker

  • Yes, it's terrible being on the meds.  I became super sensitive to anything and anyone.  The worst was just being able to sit without my pants waistband irritating the injection sites.  I actually broke out in tears and started crying at a family gathering because I couldn't sit on the sofa...and DH had to abruptly take me home and put me in bed.  How embarrassing!
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  • I was emotional but I honestly don't know if it was from the meds or everything that I was going through. IVF is so stressful as it is. The worst part for me was how uncomfortable my abdomen felt in the end.

    TTC #1 since 8/09, Dx MFI 4/10
    IUI #1: 6/10 = Cancelled, IUI #2: 7/10 = Cancelled, IVF #1: 9/10 = BFP
    Baby girl arrived - 6/14/11

    TTC #2
    IVF #2 - Oct/Nov 2012: 11/5 - eSET - 7 Frosties - BFP
    Baby girl arrived - 7/17/13 


    TTC #3
    FET #1 6/21/18



  • DrRxDrRx member
    When I did IVF, it wasn't so much moodiness but that I would cry at songs playing on the radio when I was in my car.  Or have a really good ugly cry when watching a movie a-la Notebook.  That's as far as the emotional side effects that I noticed.  There are also the physical side effects that I had--the hot flashes, enlarged ovaries, etc, that while not awesome, they were definitely manageable.  I worked during my entire stim cycle. 

    Good luck!
    TTC Since July 2008.
    Me: PCOS DH: Low everything (MFI)
    Clomid with TI x 3 2010 BFN
    Clomid+IUI+Ovidrel 2010 BFN
    IVF w/ICSI #1 2011
    9/8/11 Beta #1: 2082!! 9/19/11 Beta#2 34,689!! U/S 9/22/11 HR 127! 11/8/11 HR 150! 12/6/11 HR 136! 12/14/11 HR 139! Born at 26w2d on 2/4/2012! After 83 days in the NICU, Adalyn came home on 4/26/12!
    FET 1 3/2013 BFN
    FET 2 5/2013 BFN
    Lilypie Premature Baby tickers
  • Clomid made me an emotional, anxious wreck. Femara was better, and though it wasn't easy, per se, my IVF cycle was actually the easiest in terms of physical and emotional side effects. Which kind of surprised me. Aside from the general stress of the cycle, I felt pretty balanced emotionally.
    4 IUIs: Bfn
    Antagonist IVF 7 retrieved, 4 fert w/ICSI&AH, 2 blasts transferred. Beta #1 9/20: 367 Beta #2 9/22: 841
    image image
  • ccamccam member
    edited August 2013
    Oops....damn mobile!!

    ___________________________________________________________________________

    Trying for #1 since May 2010   l   DX ~ Unexplained Infertility June 2011

    IUI #1&2 = BFN; IUI #3 = BFP, m/c @ 6 weeks

    November '11 ~ IVF#1 ~ ER 11/18 (29R, 17F) ~ 5dt of one beautiful blast on 11/23 = BFP!!

    Beta #1 9dp5dt = 116, P4 = 28 ~ Beta #2 13dp5dt = 700 ~ Beta #3 20dp5dt = 9500, P4 = 26

    1st u/s 12/27 - hb of 156!! EDD 8.10.12 :)   **TEAM GREEN!**

    Sweet baby boy born 8.18.12

    Baby Birthday Ticker Ticker

    Trying for #2

    FET #1 - October '13 - c/p   l   FET #2 - December '13 - cancelled :(   l   FET #2.2 - 1.30.14 - BFN

    ~ More testing - hysteroscopy, endometrial biopsy & more b/w - all normal / negative~

    Surprise BFP while waiting on FET #3 ~ beta #1 500; beta #2 1600; first u/s 4/3 - measuring 5w5d, no hb yet!; 2nd u/s 4/10 - hb 132, measuring 6w6d - EDD 11.29.14 :)    **TEAM GREEN!**

    Beautiful baby girl born 11.24.14

      Baby Birthday Ticker Ticker

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