TTGP Mid-Week Update 2/20

britters314 · February 20

**The questions posted here will be pretty generic, so feel free to add other questions/info that are pertinent or delete what isn't. Please err on the side of caution and use trigger warnings/spoilers for topics that may be sensitive for other users.**

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.):

WTO/TWW:

Timing/Testing/CS:

How are things going? Any questions?:

R/R:

virginiaham · February 20

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.): Femara/cocktail/TI cycle

WTO/TWW: WTO CD15, monitoring US today

Timing/Testing/CS: we’ll keep up the timing as long as MH is home, this is gonna be a close one 😅

How are things going? Any questions?: We had that ice/snow that blew through the southeast and thankfully my Dr is only rescheduling to later today and not canceling my monitoring US. I’m not taking mucinex and my CM already looks way better than last cycle so I think that was the right choice.

R/R: The storm meant MH was home yesterday and today, and no point in him going in Friday. It feels like a gift to have the extra time together.

britters314 · February 20

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.): TTA while waiting for our embryos

WTO/TWW: WTO (CD 12)

Timing/Testing/CS:

How are things going? Any questions?: We accepted the match we got for embryo adoption! Next step is the embryology report gets sent to our clinic and they decide if they’ll accept the embryos.

R/R: It’s been like -20 windchills this week and we all have a bit of cabin fever here. Excited for it to get a bit warmer this weekend

emeraldcity603 · February 20

@virginiaham I’m glad your monitoring session didn’t get canceled. Enjoy the extra time with DH!

@britters314 How exciting that this process is moving so fast! -20 windchill is brutal. That kind of cold will cut through to the bone. 😩 Hopefully it warms up soon.

emeraldcity603 · February 20

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.): BD

WTO/TWW: WTO

Timing/Testing/CS:

How are things going? Any questions?: CD1 today. I was hoping my LP was lengthening some but it didn’t really all that much. I hope my ovulation is delayed some so our timing doesn’t coincide with DH’s string of night shifts.

R/R: I wish I could just lay on the couch all day. CD1 and 2 are the worst and I hate standing on my feet those days.

fifilala516 · February 20

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.): BD

WTO/TWW: WTO

Timing/Testing/CS:

How are things going? Any questions?: it’s CD2 which means my luteal phase was only a week. Now that I’m actively charting I want to see if this is a pattern - for those who’ve been there, how did you determine what the cause of a short LP was? What were the steps to try to rectify it?

R/R: Thursday is the most chaotic day of my week but I’m off tomorrow so that is good.

aisleofviewtwo · February 20

@virginiaham FX for good US monitoring results today! I hope everything's right where it needs to be and you can relax and enjoy this time with your husband without the stress of timing concerns.

@britters314 Congrats on the match!!!

@emeraldcity603 Sorry to hear you've got the CD1-2 blahs. Can you do something to treat yourself and make things a little brighter until you're on the other side?

@fifilala516 That would be a really short luteal phase. Am I remembering correctly that you thought you were in the fertile window and/or had already ovulated, then Inito suggested it occurred a week later? If so, I'd encourage you to not put too much weight on what this cycle means, especially since you started monitoring mid-cycle. The machines know a lot but they don't know everything! It may take it a while to understand your hormonal patterns, or may have missed important cues in the first half of your cycle that would change how it evaluates things.

WAYDTGKU (BD/TI/IVF/FET/Benched/etc.): FET/temporarily Benched

WTO/TWW: N/A, on birth control for a few more days

Timing/Testing/CS: N/A

How are things going? Any questions?: Finally got to talk to our doctor yesterday. She's not giving up hope for us yet, so I'm try not to, either. Moving to a fully controlled cycle for the next FET, which should kick off late next week (unless I get cold feet and decide to defer to April). She doesn't really think I'm a candidate for endometritis, endometriosis, or autoimmune issues based on my medical history, but we're gonna throw some harmless and cheap treatment options into the mix this cycle just in case: daily Claritin (and maybe one other antihistamine?), and steroids for a few days pre-transfer. Her position is basically that any further testing we can do is unreliable and/or likely to be inconclusive, so better to just save the time and money and go directly for the known treatments without worrying too much about a formal diagnosis. It's a weird place for my type-A self to be, but I'm trying to be better at sitting with uncertainty.

Anybody ever done intralipids IV infusion? Or know somebody who did? My doctor seems pretty skeptical of its efficacy but said she wanted to offer it in case it would help my peace of mind.

R/R: I haven't been baking recently, even though I love it, due to my current gluten-free, sugar-free lifestyle. But a family member had a birthday over the weekend and I called dibs to make the cake! It turned out so well!! I even managed a chocolate ganache drip that looked halfway decent. And I was pleasantly surprised by how much I enjoyed getting to serve it to others and seeing how much they loved and appreciated it, even though I wasn't partaking myself.

britters314 · February 20

@fifilala516 I wouldn’t worry about your LP until you’ve charted a whole cycle. I forget - did you recently come off birth control? If so, that could be a cause of weirdness in your cycles that could go away after a few months.

fifilala516 · February 20

@aisleofviewtwo Good point! I thought for sure I was ovulating like Days 10-12 or so but according to Inito it was Day 17, which seemed late considering my cycles have been ~25 days. Hopefully charting the entire time this cycle will give me perspective.

@britters314 Nope, I haven't gone off BC recently. But weirdly my cycles have been short (around 23-25 days) for the last few months.

virginiaham · February 20

@aisleofviewtwo I was supposed to do intralipids but because of a soy allergy I’m doing the prednisone instead (mine is for elevated natural killer cells, and yeah that was a pricey test). It sounds like she’s hitting the “kitchen sink” protocols with the Claritin + other antihistamine and offering the intralipids. If you’re up for it my take is, it’s worth a shot. Is she having you do Lovenox as well? That’s the one thing my Dr hasn’t prescribed that I want to ask about.

Monitoring results — endometrial stripe was 10.1, 2 follies 18mm & 18.5mm, estradiol elevated so that’s good. OPKs all completely negative still. My lab just came back this evening after the office closed and I’m wondering if he’ll have me trigger this time.

virginiaham · February 21

No trigger, just keep checking OPKs and blood draw on Monday to confirm ovulation. 🤷🏻‍♀️ CD16 and still completely negative OPKs 🙃

aisleofviewtwo · February 22

@virginiaham Man, I wouldn’t have guessed a soy allergy could affect this many aspects of ART. Today I learned! The steroid they’re putting me on, medrol, seems to have some similarities to prednisone, which is maybe why my doc was a bit ambivalent on adding the intralipids infusion on top? I’ve asked for more info on pricing, since the bottom line may be what it comes down to for us.

No mention of Lovenox so far here. Do you have known issues with blood clotting? Or does it have a different use in TTC?

FX those OPKs turn positive for you pronto!!

virginiaham · February 22

@aisleofviewtwo I think there is still some skepticism re intralipids with not necessarily strong research definitely backing it and I think they still don’t know exactly why it works. But, it has been shown to increase pregnancy rates in RPL and implantation rates with repeat implantation failure, though yeah there might be a redundancy factor if you’re already taking medrol, though I imagine it works in a bit different way so coming at the immune system from a different angle? I’m curious to hear if it’ll be affordable — and I hope it is if it’s something you’d like to do!!

eta oh girl this soy allergy, I have learned so so much cutting it out of my life 🙃

TW loss

My labs don’t show a clotting disorder but it’s sometimes prescribed in cases of RPL as a might help/won’t hurt. We’ve had 7 losses… I’d hate to go through all of this without Lovenox and have another loss later on and find out *then* that we should add Lovenox too. I’m 38, let’s throw all the things and the kitchen sink at this 😜

I just ran across a CNYfertility article “Egg + Implantation Enhancement and Immune Protocols” that goes over allll of the things…it’s the first article I’ve seen that covers all of the kitchen sink stuff, but it’s a good read.

virginiaham · February 22

Still negative OPKs. I’m feeling completely deflated 😓

emeraldcity603 · February 22

@virginiaham what CD are you? Any time I have used OPKs I feel like I wait in vain for ovulation.

virginiaham · February 22

@emeraldcity603 CD17…based on my scan on Thursday I’m pretty sure everything was good to do a trigger injection that day to stimulate ovulation but we are going by my body’s own ovulation. I O’d on my own last cycle on CD16. I’ve been doom-scrolling Reddit threads on Letrozole anovulatory cycles and LH suppression; apparently suuuuuper light LH strips and short surges are a thing with Letrozole. My CM/CP is good still though. Our last possible timing is early tomorrow morning 🫠

It was humorous explaining to MH this morning that I wasn’t in fact crying over him leaving but that I was crying over my stupid lack of ovulation. He sweetly offered that maybe it’ll still happen later today or tomorrow. And then offered to freeze a sample just in case lol.

emeraldcity603 · February 22

@virginiaham that is frustrating that that drug causes a light/short surge. Do you think you could have missed it?

virginiaham · February 22

I’ve been doing OPKs around the clock since Tuesday so I don’t think I missed it. I’m doing the mental math of 1-2mm follicle growth per day, and if no surge by Monday it would possibly be max 26mm which I think is still ok / not post-mature. If I don’t have a surge by then I’ll call the clinic and ask them if I can re-scan/trigger.

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