NIPT says boy, sono says girl

knottie9c67feb8c67b804c · September 2023

I did the NIPT blood test at 11 weeks and it came back male. I’ve had 2 sonograms (13+1 & 15+4) and 3 ultrasound techs say with 99.9% certainty that it is a girl. What do I believe?

cioccolata16 · September 2023

Oh dear! So, granted I'm new to this, but I was under the impression that until the anatomy scan (so 18-20weeks), ultrasounds can be a bit hit-or-miss for identifying gender. NIPT should be more accurate particularly for a boy, because it identifies fragments of the baby's DNA in your blood sample. The only reason there would be a Y chromosome in your blood, is if you had a male fetus hanging out. This paper apparently found NIPT is 99% accurate is identifying fetal sex.

I'm been wondering if something similar might happen when I go in for the anatomy scan in a week and a half. My NIPT predicted a girl, but that's a bit less certain than a boy, so there's still a chance the US could show something different!!

Mackie FL, Hemming K, Allen S, Morris RK, Kilby MD. The accuracy of cell‐free fetal DNA‐based non‐invasive prenatal testing in singleton pregnancies: a systematic review and bivariate meta‐analysis. BJOG. 2017;124(1):32‐46.

Also this: https://www.thebump.com/a/ultrasound-wrong-gender

ceclarlinetlo · September 2023

I have a friend who was told after multiple ultrasounds (including a 3D one) that she was having a girl and that baby came out a boy. I would trust the DNA test over ultrasound.

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NIPT says boy, sono says girl

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