follistim and Gonal F Overfill

Re: follistim and Gonal F Overfill

• optimistgardener member

  December 2021

  hi @anivad21! speaking as a fellow IVFer who has used the overfill on Gonal F pens, I appreciate your tip! If you'd like to join our community please read our Newbies guidelines and introduce yourself in our weekly Newbies thread. We're a pretty organized little community around here and typically don't do one-off threads like this, but this is the kind of post we'd welcome (esp. after you introduce yourself!) in our weekly IF thread here in TTGP. You might also check out the Infertility board (but they also have board-specific rules you'll want to check out).
  

  History

  I am doing this on my own. Left ovary and fallopian tube removed due to cyst/necrosis just after birth. Right ovary and tube still purport to function.

  Began TTC in Aug '18 @ age 35

  5 or 6 (or 7?!) cycles using frozen donor sperm, ICI. All BFN

  Mar-Jun '19 IUIs, all BFN
  

  Began process of referral for RE in spring of '19, blood tests confirm low AMH (.54) but all else is good.

  May '19 HSG shows open tube, but ultrasound suggests fibroids
  

  MRI in June '19 confirms two large fibroids, one growing through wall of uterus

  In June '19 I move from California to Oregon, disrupting my insurance, referrals, etc. 5 months spent piecing it all back together.
  

  Nov. '19 attempted myomectomy (vaginal approach) failed. 2nd surgery using laparoscopic method in Jan '20 is successful.
  

  April '20 --> June '20, natural IUIs, all BFN.

  July? saline ultrasound and bubble test demonstrate open tube
  

  July '20 clomid cycle cancelled for thin lining

  Aug-Oct, 3 femara cycles, all BFN

  RE referral. While waiting to set up an appointment Nov-Jan,I continue with natural cycles and ICI, using a known donor, BFN...
  

  Jan '21 more bloodwork, AMH is worse (.30), FSH high albeit not catastrophic at 13.2. hysteroscopy all good. "looks cozy!" says the RE.
  

  Feb '21, injectables (menopur, novarel), iui, BFN (doc said the frozen donor sperm sample had the "best numbers she'd ever seen!")
  

  Mar '21, injectables, iui cancelled due to lack of follicles, converted to at home-insem. BFN
  

  May '21, first IVF round cancelled due to cyst.

  July '21 IVF: standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 7; 6 days of stims. 8 eggs retrieved, 7 mature, 5 fertilize, 4 made it to blast. 3 are 4AB, 1 is 4BB. PGT-A results all abnormal.
  Oct '21 somewhat improved AMH (.51) and significantly improved FSH (8.9). Maybe it's all the pills I swallow.
  Dec -21, standard antagonist. 225menupur/225gonal-f/cetrotide/5000u trigger, AFC 5; 11 days of stims. retrieval yields 5, 4M, 2 reach day-6 blast (4AB & 4BB). 1 low-level mosaic (chr. 3 deletion), 1 complex abnormal.
  Feb '22 FET (low-level mosaic): CP.
  May '22 egg retrieval, lupron flare protocol. HGH priming for 1 month before stims; md lupron 20/20u daily; menopur 225, follistim 225, 10k trigger after 8 days of stims; AFC 10; 13 retrieved; 10 mature; 8 fertilized. All frozen at 2PN for later thaw, grow, and biopsy.
  July '22 egg retrieval same protocol: 9 days of stims; AFC 8; 10 retrieved, 8 mature, 4 fertilized and frozen.
  Sept '22 ER same protocol: AFC 10; 12 retrieved, 11 mature, 11 fertilized.
  From the 3 retrievals, 7 survived to day 5-6 blastocyst, from which I have 2 normal embryos!
  Jan 20, Fully medicated FET, baby aspirin, dexamethasone, acupuncture, and as much woo as I can stand (which isn't very much). BFN.
  July 23, Natural FET + baby aspirin. BFN.
  

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