Trying to Get Pregnant

IF Testing and Treatment w/o 8.17

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Re: IF Testing and Treatment w/o 8.17

  • @emeraldduchess I don't wear contacts anymore (thank you, lasik!), but they asked me repeatedly if I was wearing them on my ER day. So I think glasses is probably the best bet, but your clinic might be different. 
  • @shoogapoff thank you! I hate wearing my glasses outside of my house, but I am obviously not driving myself so it won't matter. I can always ask when they give me instructions about the procedure. My clinic has just been telling me things step-by-step. 
    I got today's blood test results and my estradiol went down just a teeny bit, so they're bumping up my meds again to 300 of Gonal-f and 4 vials of Menopur. I go in again tomorrow for monitoring and may be triggering tomorrow evening. I honestly didn't think I would respond as quickly as I have since I tend to O around CD20 or later. 
  • Loading the player...
  • @emeraldduchess It's not like they're going to have you walk around blind! They'll have you wearing your glasses the whole time. I'm not even sure I know the reasoning behind not having contacts in (I guess cuz they could get lost in your eyes while they're closed? idk). Wear your glasses, you'll be fine!
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • Thanks, @inthewoods23. I know I won't just be wandering around.  :D My worry is that my glasses will get lost. Maybe I won't even have to take them off? LOL I am thinking too much about this!
  • @emeraldduchess there is no reason for your glasses to be off for the procedure! You are thinking too much about it 😂
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • *lurking*

    I’m not sure what they do for sedation, but I have seen someone get a bad corneal abrasion from contacts with conscious sedation. Not worth the risk! Go with glasses! 
  • legallykatelegallykate member
    edited August 2020
    @emeraldduchess I have terrible eyesight and usually wear contacts but wore glasses for mine. I didn't have to walk around by myself at all, I got hooked up to the IV in a waiting room and then two nurses helped me navigate with the IV stand to the procedure room, and then I woke up back in the waiting room (on a bed). Then I was able to put my glasses back on once I was awake. I have had two corneal abrasions from sleeping in contacts and like @fitzfizz said totally not the risk even though you are only "asleep" for like half an hour. 
    *TTC History*

    Me: 37, MH: 38; Married August 2017

    TTC #1 October 2017: BFP on 12/1/2017, DD born 7/24/2018 @ 37+1 after induction due to preeclampsia

    TTC #2 January 2020: AMA, dx with DOR in May 2020

    IVF July 2020: 16 eggs retrieved, 14 mature, 12 fertilized, 3 blasts, 2 PGT-A normal

    FET 10/7/20: BFP on 10/12/20!!! (EDD 6/25/21); First beta 10/16/20 (9dpt): 148; Second beta 10/19/20 (12dpt): 621; Third beta 10/26/20 (19dpt): 4732; Fourth (and final!) beta 11/2/20 (26 dpt): 22,000+

  • @inthewoods23 overthinking? Me?
      
    ;) Yes, I probably am. Good point, it's not like I'm being put under completely so I shouldn't need to take them off. 
  • @emeraldduchess Better than underthinking I'd say, there is way too much of that going around these days!
    *TTC History*

    Me: 37, MH: 38; Married August 2017

    TTC #1 October 2017: BFP on 12/1/2017, DD born 7/24/2018 @ 37+1 after induction due to preeclampsia

    TTC #2 January 2020: AMA, dx with DOR in May 2020

    IVF July 2020: 16 eggs retrieved, 14 mature, 12 fertilized, 3 blasts, 2 PGT-A normal

    FET 10/7/20: BFP on 10/12/20!!! (EDD 6/25/21); First beta 10/16/20 (9dpt): 148; Second beta 10/19/20 (12dpt): 621; Third beta 10/26/20 (19dpt): 4732; Fourth (and final!) beta 11/2/20 (26 dpt): 22,000+

  • I was gonna lurk this week since we're almost at the end of it and I just got back, but then decided otherwise. 😆#addicted

    @emeraldduchess I'm v. excited for your ER on Sunday. What's your current follicle count? Also, when I did my ER for freezing, I had mild conscious sedation, not general anesthesia. I personally enjoyed it because of the science-y aspect (being able to see the aspiration). I hope you will too. 

    @legallykate how rude of your ovaries to make you suffer an extra long cycle! 


    @misshelen86 it's so great that you were comfortable enough to let your manager in on your IVF plans. So glad she was supportive. Would you have shared if your manager was a man? 

    @kiki047 🤞🏻that this is gonna happen for you in the next 2 weeks! MH refers to the human body as a "disaster of engineering" and I 💯 agree with him. 

    @inthewoods23 I am sorry that the 2nd opinion didn't give you more hope. 5% naturally sounds so darn discouraging. Like... why? I hope that your going on my medication for stress/depression/anxiety will do the trick. I'm really keen to hear how your baselines measurements have improved with all the great work you've put into lifestyle improvements. 

    @runningoncookies I am sorry to see you here. Enjoy your vacation, and hopefully one more month of trying naturally is what you need!

    @akoros I sometimes share your feelings re: do I belong on this thread or not; in fact even today I re-read the thread intro just to be sure. Alas, you are definitely in the right place as this community is so welcoming and soothing. And, allow me to get science-y/nerdy for a bit, I've recently learned that there's a difference between fertility and fecundity. The latter, is your physiologic ability to bear children, which you have since you can conceive. The lack of fecundity is sterility. However, fertility is actually the output of reproduction; and hence since you have been unable to carry to term, you do have infertility. 

    @shoogapoff how far from CD1 are you? I am hoping so hard that this FET works for you and that you have a very healthy baby. 

    @ramzlau Good luck with your IUI(s). How was YH's sperm? How are you feeling? Unfortunately I don't have any opinion/knowledge about success rates for double-IUI given the washing aspect. I have purchased FertilityIQ's IUI course which I intend to review today, so if I learn anything there, I'll share. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • AFM... (this is gonna get ranty)

    Diagnosis (if you've been): PCOS (in my 20's)... more on this below; my RE claims "unexplained"; NaPro OB says "Late Luteal Phase Defect". Take your pick!

    Status (WTO/TWW/TTA): TWW

    What are you doing this cycle? (Testing? Treatment?): completed our final tests; met with RE yesterday to plan next steps; talked with the genetic counselor from Myriad (the supplier our genetic tests) this morning. Now, just waiting to see if a) we succeeded on our own this month; or b) ceasing taking progesterone tomorrow, waiting for CD1 and starting the IUI process!

    How are things going?: Okay, so easy stuff first. Met with the genetic counselor this morning to review the genetic results that we received last week (I am a carrier for Nephrotic Type 2 disease) and the counselor said that since MH is NOT a carrier, then chances that our baby(ies) would have it is effectively none; it basically equates to the chance of the genetic testing for MH being wrong, and those chances are <1 in 1M. But, there is a 50% chance that our babies would be carriers of same disease.  

    Slightly harder stuff: had a f/u with our RE yesterday and still really like her, feeling positive about working with her. The plan remains: superovulation w/ Clomid + IUI. Btw, @inthewoods23, she too confirmed that chances of IUI working is 12-15%. Pretty freakin' low. 🙁 Insurance doesn't cover any IF treatments for us, so we'll be paying out of pocket. I also asked her if double-IUI would increase our chances, and she basically said that not really, and since we're self-pay, it's not worth it for us to pay the extra money to do that. So, next steps here is signing consent forms, WFAF (or maybe not? 🤞🏻maybe I've scared my body into doing what it should do?!), and then it's off to the races. Really feeling confident about this clinic and our RE. 

    Finally, PCOS... I've been doing a lot of reading about this since it comes in so many shapes and sizes. And I'm pretty sure I have something called haPCOS (hypoandrogenic PCOS). Let's start with the fact that I've definitely had been diagnosed with PCOS at age of 25 b/c I had cysts. Then fast-forward to current day, and u/s that show no cysts, androgen panels that come back normal and, in fact low-range, of normal (my testosterone was below ref range). Then, a person from the other fertility community I'm in – Modern Fertility – suggested that I exhibit symptoms of haPCOS and pointed me to the research done by Center for Human Reproduction and I found this case study: https://www.centerforhumanreprod.com/fertility/the-hypoandrogenic-pcos-patient-the-monthly-case-report/. Other than the fact that I'm not 43, this case study very closely matches my symptoms.  Most importantly is this line from this report "low intra-ovarian testosterone levels adversely affect early stages of follicle maturation." Which... hello... the reason NaPro said I have luteal phase defect... because my follicles under-develop and don't "properly" release an egg ("weak ovulation"). Anyway, I just e-mailed the RE and asked to have my SHBG tested. And if she doesn't want to, I'll just order it myself from Walk-In Lab. 

    Any questions?: Am I the only one with this unyielding desire to get to the bottom of my fecundity issues? Like before we start throwing treatment at the problem, can we just figure out what's wrong? Blergh.

    GTKY: What are some good movies you have watched recently? Like @ramzlau, we watched Star Wars about 2 months ago and loved it. Also, like @akoros, watched Ford vs. Ferrari and loved that. Last week we watched Radioactive on Prime and it was pretty good/educational/makes you think (about the positives and negatives of Marie/Pierre Curie's discoveries. Also that Curie family is freaking talented! Her daughter/son-in-law won a Nobel prize as well! 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @acleverusername I don't know how "out" I will be, but I had a lymph node biopsy 9 years ago that was supposed to be conscious sedation...I slept right through that.  :D Considering it only take me like a glass and half of wine to get buzzed, I will probably nod off or I just won't remember it at all. 

    So I am not triggering tonight like I had hoped, which means ER will either be on Monday or Tuesday. And of course I got a call about an interview on Tuesday. I asked about rescheduling for later in the week due to a possible medical procedure, the administrative assistant checked and they can't do that, so I left a voicemail (and emailed...desperate much?) asking if I could sign up for a time for Tuesday and if I have to cancel, I will let them know. Of COURSE my ovaries are now messing with my life outside of TTC. 

  • @acleverusername Welcome back!  Like you, I've actually been out of this thread all week.  Too much work on my plate and not sure I've kept up with the lurking here.  Sounds like you've really done your homework!  Hope you continue to get answers to the underlying issues!

    @emeraldduchess I can NOT believe the timing of your ER and interview next week!!!  Can the universe not give you a break already?!?! I mean, I do believe it because these things seem to always happen once everything gets lined up correctly.  Anyway, I hope that the scheduling becomes a non-issue next week and that everything does indeed fall into place perfectly.

    @inthewoods23 I'm sorry the second opinion appointment left you feeling down.  But reading your updates, it sounds like a lot of good really came out of that appointment and the therapy appointment. it sounds like you and the RE have a really great plan for moving forward!  I hope you are starting to feel a bit better about it today. <3

    @ramzlau FX for the back-to-back IUI success!  Exciting!

    @akoros I definitely tiptoed in here for awhile in the beginning.  But others who had also experienced RPL reassured me that we do belong here.  And all my paperwork at the RE does say Infertility: RPL at the top of the page.  So yes, you are more than welcome here.

    **I will come back later for more tags.  Deadlines to meet today!  No updates on my end.  Still in the nothing-happening TWW...


  • @emeraldduchess oh man... why can't you get a break!?! I hope it all works out with interview and ER. FX!
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • edited August 2020
    @keikilove I KNOW, RIGHT??!!?? I am telling myself that if the interview timing doesn't work out, then it's not meant to be. I have to put family over work. 

    @acleverusername we were given low odds on IUI too, but we wanted to try it before going straight to IVF because *TW* we did get KU twice but they ended in early losses (CPs). That's really interesting about haPCOS. I never heard of that before. Definitely pursue that testing with your RE! 

    I didn't hear back from the admin. assistant, but most school offices close up shop around 3:30pm, so hopefully she can get back to me on Monday. I am SO over these stims and this job search. 

    Edit to add update: The nurse at my RE's told me I had at least 2 follies measuring 16mm today. I assume that's good? I don't know how many I have total or what they measure. I go in for another u/s and blood test tomorrow. Crossing everything that things are moving along!
  • edited August 2020
    @ramzlau so, the FertilityIQ course on IUI's didn't really give much more information about how sperm washing might affect double IUI success rates when there's sperm agglutination. In terms of effectiveness of double IUI (as you said, no better than single), they cited these two studies: https://pubmed.ncbi.nlm.nih.gov/19665705/ & https://pubmed.ncbi.nlm.nih.gov/12535490/). However, I think sperm washing technique might have something to do with IUI effectiveness overall... do you know what method your clinic uses? Anyway, study about this here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156944/ and information about the different technique here: https://www.intechopen.com/books/artificial-insemination-in-farm-animals/sperm-preparation-techniques-for-artificial-insemination-comparison-of-sperm-washing-swim-up-and-den

    I hope this helps. 

    P.S. The FertilityIQ IUI course has really good info and worth the $49 IMHO. 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • @emeraldduchess YEEESSSSSS!!!! Finally, some GREAT news!!

  • Amazing news! Yay @emeraldduchess!!! 
    MY CHART
    TTC History
    TTC#2
    Me: 40.5; MH: 39 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #2 ... preparing as of March 2024


    TTC #1
    Me: 36, MH: 34 | Met 02/2009 | Started Dating 08/2017 | Married 02/02/2020
    TTC #1 02/2020 - 07/2022
    2009 | Dx PCOS; likely a misdiagnosis
    07/14/20 | Dx Hashimoto's Thyroditis
    07/21/20 | 1st RE appointment
    07/2120 - 08/20/20 | so much testing; no signs of PCOS
    08/20/20 | Dx Unexplained; AMA
    09/08/20 | IUI #1 Clomid + Trigger + Prometrium | BFN
    09/30/20 | Urology consult; more testing required
    10/2020 | Clomid + OPK + TI + Prometrium | BFN
    10/26/2020 | Starting 2nd IUI cycle, with Letrazole and with a new RE / different clinic
    11/03/2020 | New Dx "poor egg quality"; IUI cancelled in favor of Trigger + TI + Prometrium | BFN
    11/26/2020 | Combo IUI (Clomid + Menopur) + Trigger + Prometrium | BFN
    12/20/2020 | Combo IUI (Clomid + Gonal-F) + Trigger | IUI Cancelled due to thin lining; TI only | BFN
    01/14/2021 | Combo IUI (Letrazole + Menopur) + Trigger | BFN
    02/06/2021 | Switched to a new RE (TEW) ; trying naturally until we complete additional testing 
    03/14/2021 | Hybrid Double IUI, with Zymot (Letrazole, Gonal-F) + Trigger + Endometrin | Ovulated 4 mature eggs but still a BFN ☹️
    04/07/2021 | Natural cycle while we regroup | BFN
    04/09/2021 | Employer announces fertility benefits starting 05/01/2021! | Search for a new doctor who accepts insurance
    05/10/2021 | New RE consult & plan for IVF
    05/13/2021 | Mid-luteal IVF cycle #1 interrupted; had to get cancer genetic screening done to make sure I didn't have the same SDHA gene mutation as MH. 
    06/10/2021 | Aygestin priming IVF cycle #1; opted to Cx after 9 days of stims since only 5-6/12 follicles responded
    07/26/2021 | Attempt #2 at IVF cycle #1 (mid-luteal start): 8 retrieved, 8 MII, 6 fert (1 PN3), 3 Day 5 & 6 blasts: 3AA, 3AA, 6AB; 3 euploid
    08/09/2021 | Rest cycle / unmedicated TTC | Shockingly, a BFP! EDD: 5/25/202 | CP at 4w4d
    09/23/2021 | IVF cycle #2 (mid-luteal start): 14 retrieved, 13 MII, 11 fert, 5 Day 5 & 6 blasts: 2 x 3AA, 2 x 3AB, 3BB; 2 euploid
    11/12/2021 | IVF cycle #3 (mid-luteal start): cancelled due to ovaries being on vacation
    12/20/2021 | Rest cycle / unmedicated TTC + Pregmune Immunology Testing; BFN
    01/22/2022 | Rest cycle / unmedicated TTC + understanding uncovered immunological issues; BFN
    02/18/2022 | Mock transfer cycle! ERA, ReceptivaDx, EMMA/ALICE; start Prednisone to address NK activity
    03/16/2022 | Final, "Hail Mary" super-ovulation + TI cycle before FET; BFP! EDD: 12/21/2022 | MMC 05/08/2022
    05/20/2022 | D&C; recovering... 
    06/21/2022 | Trying naturally until October 2022
    07/21/2022 | BFP! EDD 04/02/2023; 👦🏼 born on 4/5/2023


  • inthewoods23inthewoods23 member
    edited August 2020
    @emeraldduchess YESSSSSSS

    Also sloth socks FTW!!
    *TW* History:
    Me: 34 DH: 36 | Together since 2007 | Married July 2016

    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC put on pause
  • @emeraldduchess YES GIRL!!! This is amazing news!! Grow follies grow! 

    Me: 35 DH: 35
    TTC since 9/2018
    Dx: MFI
    10/19- First RE visit
    2/20- DH had surgery for bilateral varicoceles 
    7/20- IUI with 5 mg letrozole- BFN
    9/20- IVF. 9 eggs retrieved, 9 mature, 8 fertilized with ICSI, 7 blasts, 4 PGT-A normal
    11/20- Mock transfer/ERA
    12/20- FET #1- transferred one 4AB- BFN
    3/21- FET #2- transferred one 3AB- BFP! Due Dec 2021
    12/21- Baby girl born!

  • @emeraldduchess yesss girl! 👍👍 this is fabulous news! Woo hoooo
  • @acleverusername I admit, I forgot the word "fecundity" existed, let alone the distinction. Thank you, and thank you to everyone who have been so supportive. When I'm in the throes of grief I tend to get tunnel vision and can only think of myself, which I'm emerging from and started to second-guess things I said or did while I was being self-centered. I definitely don't want to hurt or make anyone uncomfortable, and now that I have a clearer head I wanted to check. 

    @emeraldduchess Glad you've gotten good news! The COVID test is weird...the nurse explained it to me very well, but still didn't make sense in my head that I see a swab go "up" my nose and then I feel it in the back of my throat (but the top of my throat, which is not a place I "feel" very often).
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