Success stories with early blast transfers? — The Bump
Pregnant after IF

Success stories with early blast transfers?

Hi ladies, I was here back in 2017, we had done a fresh transfer with an expanded blast and my daughter was born in 2018. Since then we've had two FET losses.
We ICSI'd our remaining frozen eggs, and ended up with only two early blasts at day 5. We decided to transfer both to give them the best chance. 
I'm feeling really discouraged, as our last FET failures had been early or full blast at day 5 but we frozen them as expanded blasts on day 6.
Does anyone have a success story transferring an early blast? Feeling a little hopeless right now...

Me 34 DH 36 Married since July 2010 
MFI (High DNA Fragmentation) & Mild endometriosis
TTC #1 since June 2015 
Aug 2016 - May 2017  6 IUI's with letrozole - BFN
April 2017 - laparoscopy to remove mild endo
June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
May 2018 - Baby girl born - Our Joy

TTC #2 since July 2019
July 2019 - FET - BFN
Jan 2020 - FET - canceled due to family health issues
Mar 2020 - FET - low beta - chemical pregnancy
July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy


BusinessWife

Re: Success stories with early blast transfers?

  • I have no experience with this, but I just have to say how excited I am for you, and how happy to "see" yer face!!! ❤️❤️❤️

    When did you transfer?  How soon do you test?  I am rooting so hard for you, love!

    Me: 37 | DH: 43 ~ TTC Our First May 2015 thru Dec 2017
    A Brief Summary of Our Infertility Journey
    5/16 - Began Creighton Method CM Tracking / Napro Fertility Medicine | Progesterone + various abx cycles - all BFNs
    8/16 - SHG: ute good, at least one tube open | 10/16 - MFI Azoo dx confirmed. No known genetic cause. Vas deferens absent.
    3/17 - DH started Clomid to prepare for MESA/TESE | 4/17 - Initial RE Consult for me | 7/17 - Successful retrieval for DH!
    9/17 - Two BTB IVFs  | 10/17 - Polypectomy  |  11/17 - 1st FET ended in CP | 12/17 - 2nd FET ... BFP!!! <3 EDD: 09/09/18
    Our little miracle is finally here!

    Our Journey Trying for a Sibling still in progress...
    9/19 - 1st natural FET cycle, BFN | 10/19 - 2nd medicated FET cycle, cancelled
    11/19 - 3rd natural FET cycle, BFN  | 12/19 - 4th natural FET cycle... BFP!!! <3 EDD: 08/21/20

  • @BusinessWife Thanks friend! We transfered them on wednesday (July 28th). I'm not feeling very hopeful, after our two previous FETs failed with nice expanded blastocysts. Our doctor said we had a 25% chance with one and 40% chance if we put in both. We aren't likely to do another egg retrieval. Maybe we would look into embryo adoption or infant adoption. I don't know. Thanks for your thoughts!

    Me 34 DH 36 Married since July 2010 
    MFI (High DNA Fragmentation) & Mild endometriosis
    TTC #1 since June 2015 
    Aug 2016 - May 2017  6 IUI's with letrozole - BFN
    April 2017 - laparoscopy to remove mild endo
    June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
    Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
    5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
    May 2018 - Baby girl born - Our Joy

    TTC #2 since July 2019
    July 2019 - FET - BFN
    Jan 2020 - FET - canceled due to family health issues
    Mar 2020 - FET - low beta - chemical pregnancy
    July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy


    BusinessWife
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  • BusinessWifeBusinessWife member
    edited July 31
    (((hugs))) It is so hard on our poor hearts with so much on the line.  I know we both had concerns about not making "too many" embabies in the first place, and it just makes me so much more grateful for our first THB - we really are already the lucky ones. ❤️ I'm not sure how much you may have been lurking at the time, but

    TW
    We also lost two beautiful blasts prior to transferring this sticky little wicket.  Both well-graded, non-PGS, but still.  And at the time, I remember asking my doc if we should be doing any other testing prior to our next transfer, ERA, idk what else!? And she just said, if there were something else we needed to do, we would have done it.  She said she truly believed we just hadn't gotten to our lucky winner yet. 😓

    It was so hard to trust and believe, and literally just try the whole FET process One. More. Time.  But you know what?  She was right!

    Statistics are so hard too, because they are just numbers, and YMMV.  Anybody could end up on the right or the wrong side of the stat on any given cycle, which sucks - but is also awesome!??  Because whether the "chances" are 25 or 45 or 10, it doesn't really matter so long as someone decides to STICK!!!!  I will be hoping and praying for you to be on the right side of the statistics, friend. 🙏🙏🙏

    Here's some food for thought, too...
    So if you look at it that way, your chances are actually pretty awesome!  Sounds like she's giving you higher chances than a younger couple with "normal" fertility!  I mean no where in that bracket do you see anything as high as 40%.  So that's great!

    As to the rest, my understanding is embryo adoption is generally much more affordable than infant adoption, but of course it comes with its own set of challenges.  If you have the opportunity to adopt a "batch," depending on how quickly you are successful, you may still have more left over, and may have different feelings on being able to go back and continue to transfer X no. of embryos.  I have heard of clauses that will allow parents to re-adopt out any remaining embryos to another couple in need until they are all transferred, as well.

    The flip side of that is of course that it brings up the whole question of genetic parentage that I feel will inevitably come up as they are older, and how comfortable you may be having that conversation.  And the added challenge compared with other donor parents to explain that your first (or second!) child(ren) came genetically from mommy and daddy, but subsequent siblings came from another set of genetic parents, who also have other genetic siblings being raised in different families - So you run into the same open/closed adoption type of scenarios that come up and can vary from state to state even.  And there would be similar conversations around conventional adoption as well, just minus the IVF part.  It can all be totally totally worth it, absolutely!  And I think it's pretty incredible, families who go down the path of adoption, with all it's unique set of challenges!  Not a decision I know I would be able to take lightly, either way.

    More importantly, as of right now, I would say with love, let's try not to get too far ahead of ourselves. ❤️. It is still so early!!!  I will remain hopeful for you, even if that's hard for you to do yourself. (((Huge hugs)))

    Me: 37 | DH: 43 ~ TTC Our First May 2015 thru Dec 2017
    A Brief Summary of Our Infertility Journey
    5/16 - Began Creighton Method CM Tracking / Napro Fertility Medicine | Progesterone + various abx cycles - all BFNs
    8/16 - SHG: ute good, at least one tube open | 10/16 - MFI Azoo dx confirmed. No known genetic cause. Vas deferens absent.
    3/17 - DH started Clomid to prepare for MESA/TESE | 4/17 - Initial RE Consult for me | 7/17 - Successful retrieval for DH!
    9/17 - Two BTB IVFs  | 10/17 - Polypectomy  |  11/17 - 1st FET ended in CP | 12/17 - 2nd FET ... BFP!!! <3 EDD: 09/09/18
    Our little miracle is finally here!

    Our Journey Trying for a Sibling still in progress...
    9/19 - 1st natural FET cycle, BFN | 10/19 - 2nd medicated FET cycle, cancelled
    11/19 - 3rd natural FET cycle, BFN  | 12/19 - 4th natural FET cycle... BFP!!! <3 EDD: 08/21/20

  • Thanks friend, I appreciate your sound, and hopeful words 💜 yes, our chances this cycle are much much higher than if we were just trying naturally (which is probably close to 0% as we've never had a natural pregnancy in the 3.5 years of ttc.) So yes, I need to remain hopeful. We have friends who have transferred 3 pairs of day 3 embryos, they have had a negative cycle, a Singleton, and twins. So really, things could go any which way.... 
    We did a lot of research into embryo adoption before we decided to take the mini-IVF route, there are so many things to consider, just as much as traditional adoption. 
    Btw are you still team green? You must be due very soon!!! Praying for a healthy delivery for you! 

    Me 34 DH 36 Married since July 2010 
    MFI (High DNA Fragmentation) & Mild endometriosis
    TTC #1 since June 2015 
    Aug 2016 - May 2017  6 IUI's with letrozole - BFN
    April 2017 - laparoscopy to remove mild endo
    June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
    Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
    5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
    May 2018 - Baby girl born - Our Joy

    TTC #2 since July 2019
    July 2019 - FET - BFN
    Jan 2020 - FET - canceled due to family health issues
    Mar 2020 - FET - low beta - chemical pregnancy
    July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy


    BusinessWife
  • Thank you!  I will take all the T&P I can get, especially for a safe and successful vbac.  We are still Team Green (although I have my suspicions...)

    Me: 37 | DH: 43 ~ TTC Our First May 2015 thru Dec 2017
    A Brief Summary of Our Infertility Journey
    5/16 - Began Creighton Method CM Tracking / Napro Fertility Medicine | Progesterone + various abx cycles - all BFNs
    8/16 - SHG: ute good, at least one tube open | 10/16 - MFI Azoo dx confirmed. No known genetic cause. Vas deferens absent.
    3/17 - DH started Clomid to prepare for MESA/TESE | 4/17 - Initial RE Consult for me | 7/17 - Successful retrieval for DH!
    9/17 - Two BTB IVFs  | 10/17 - Polypectomy  |  11/17 - 1st FET ended in CP | 12/17 - 2nd FET ... BFP!!! <3 EDD: 09/09/18
    Our little miracle is finally here!

    Our Journey Trying for a Sibling still in progress...
    9/19 - 1st natural FET cycle, BFN | 10/19 - 2nd medicated FET cycle, cancelled
    11/19 - 3rd natural FET cycle, BFN  | 12/19 - 4th natural FET cycle... BFP!!! <3 EDD: 08/21/20

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