Trying to Get Pregnant

IF testing and treatment w/o 5/27

This is a place for those of us who have already started TTC, but have started infertility testing and/or treatments. You can express your thoughts, feelings, and frustrations on infertility. TTC can be a long journey naturally, then add in the difficulties associated with infertility, and it becomes a whole new ball game. The road to infertility can be lonely, frustrating, and complicated, so let's make this a place where we can vent, ask questions, and support one another. Feel free to resurrect this thread at any point in the week if you have something to say. Treat this as an ongoing conversation. 

Diagnosis (if you've been): 

Status (WTO/TWW/TTA):

What are you doing this cycle? (Testing? Treatment?): 

How are things going?: 

Any questions?:

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Re: IF testing and treatment w/o 5/27

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  • @inthewoods23 they didn't mention an online portal, I assume they'll either call or wait until after the CD3 bloodwork and saline ultrasound to go over results. DH is probably going to do his SA next Saturday. 
  • keikilovekeikilove member
    edited May 2019
    @littleredm Oh my goodness about your meds and the fridge!!! So glad you caught everything in time, fingers crossed! Hope the fridge is able to be repaired easily. 

    Since you posted about the pain you had during your saline sono last week and how the doc commented that sometimes it’s painful for women who’ve had endo, I have been wondering if you’ve been treated for inflammation before your IVF procedure? Sorry if this is way too in your business or an obviously stupid question. I’ve just been curious. 
  • @nitnat007 thanks for the support. Hope those SA results are what you want them to be. 

    @emeraldduchess apart from AMH I have always got blood test results same day if we go in early - next working day if the doctor has to review them before releasing them. SA was back in 2 days each time (prelim results same day - only the infectious cultures took the extra day). Genetic blood test results took around 2 weeks (karyotyping).
    Its not the speed of the tests but more the protocol for releasing results that your doctor uses that can take time.

    @inthewoods23 if you’re on low levels of Lupron (daily injections, in the range 0.05ml to 1ml - yes the range can be that wide!) then yes you should bleed as per normal - so if you get a bleed 5 days after stopping BCP without Lupron you should roughly get it the same now. However we all know we are normal until we’re not ;-)

    @littleredm oh no! What a nightmare with your fridge! Hope baseline goes well today

    @celticknotfire are you just on estrace or also on patches? I only do patches (or have so far in all rounds). When is your next lining check?

    @begging4abump if the meds stop you having a period whilst you’re on them, then yes after stopping you should get a withdrawal bleed (not a true period per se if you didn’t ovulate first). “Normally” your cycles should go back to how they were before, so worth to start tracking again after the withdrawal bleed. Of course there are always a few people who ovulate through these medications - hence why they advise to still prevent for the first week after until the meds are out of your body and once you’ve had a withdrawal bleed.
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @littleredm when it rains it pours!  So sorry you had to go through all of that.

    @emmasemm I'm only on the pills.  I start with 1/2 tablet at night (vaginally of course) then increase to 1/2 in both the AM and PM then increase again to 1 tablet in both the AM and PM.  My next check is 06/07 and then I hopefully decrease the Estrace and start prometrium and PIO
    Me:37 MH:37
    TTGP since 07/2017
    **TW** in spoiler
    DX: PCOS, anovulatory, AMA
    Femara X3: no response
    Clomid X3: BFN (cyst and thin lining)
    IUI (Dec '18) MMC
    IVF (April '19) 9 retrieved, 7 fertilized, 2 normal PGT-A
    FET 06/12/19 - BFP! EDD 02/27/20




  • @littleredm Whew. I’m glad I wasn’t overstepping boundaries by asking you about your treatment. The reason I asked is because women in my online FB groups about Reproductive Immunology often mention their Endo & the various treatments they had before successful PGs. Apparently if inflammation is present the embryo has a difficult time implanting. Here’s a somewhat short article on treatment. https://medicine.wustl.edu/news/antibiotics-may-treat-endometriosis/?fbclid=IwAR1TsaKXT8Vda5RFwkFWJANtSKGVDLkBvdl566pxyLkeq0X0qvQjh9kCJ4o

    My RE said she & many other docs treat everyone (male & female) with doxycycline in the lead-up to ER/IVF to clear any hidden infections and/or inflammation. There are other treatments too but I don’t have Endo so am not well-versed in this. Maybe our resident guru @emmasemm knows more about this? 

    Anyway, along with everyone else here, I wish you the best with everything that’s upcoming! I hope I didn’t make you nervous & feel free to send me a PM if you want anymore info on that FB group. 
  • @jennifer_louise I found that DH hated the FertilAid pills because they had a weird smell and taste yet they were capsules. He seems much happier on standard men's multivitamin that are gummies.

    He's using the Smarty Pants brand which has CoQ10 and 1 or 2 other things that aren't typically in a regular multivitamin but I believe they are known to be helpful for sperm! (Don't quote me on that because I haven't looked into that for some time!)
    *TW* History
    TTC #1 since 7.2017
    Dx: low morph (1%), ANA positive, low decidualization score, high TSH and testosterone, histone antibodies

    IUI #1-3 all BFN
    IVF #1 | 6.11.19 | 24R, 17M, 15F, 6B, PGT-A tested - 5 normal, 3 girls & 2 boys
    FET #1 | 9.10.19 | BFN "I know you, but we've never met. I'm with you, but I don't know your name"
    RPL, Receptiva, & ERA testing | all normal/negative, recommended going on gluten and dairy free diet for next FET
    FET #2 | 3.31.20 | Opted to cancelled due to pandemic, continued diet and tried naturally over the summer
    2nd Opinion with another RE | 8.20.20 | Not immune to measles (received 1 dose); SA results similar to 2 years ago; decided to move forward with FET #2 redo at start of next cycle
    Surprise natural BFP! | 9.22.20 | MC 10.23.20 at 8 weeks
    TTCAL naturally | starting 11.22.20

    Initial consultation with Reproductive Immunologist | 9.14.21
    Decidualization score biopsy | 10.1.21 | abnormal - low score of 1; endometrial scratch recommended and progesterone supplementation
    Saline sono | 10.15.21 | normal
    Bloodwork | 10.21.21 high TSH, high testosterone, positive for anti-nuclear antibodies and histone antibodies, high protein S, multiple genetic mutations
    BFP! | 11.3.21 | EDD 7.14.22 B) | biopsy provided same effect as endometrial scratch; added supplemental progesterone and estrogen, prednisone, levothyroxine, and MTX Support to maintain pregnancy
    DS born 7.19.22 after induction


    TTC #2 begins 6.2023
    Consultation with RI | 6.6.23
    Saline sono, endometritis biopsy, skin & eye check | all normal
    Labs | high TSH, Factor XIII mutation, high %CD56
    Follow up | 8.8.23 | prescribed metformin, prednisone, plaquenil, and levothyroxine
    Repeat labs after 3 weeks on meds
    Follow up | 11.9.23 | Green light!, increase in prednisone, added lovenox
    Repeat labs in 8 weeks
    Follow up | 1.16.24 | Green light continues
    TTC ended due to filing divorce

    **New relationship starting May 2024**

    Surprise BFP!! | 9.7.25 | EDD 5.11.26
    Its Gonna Be May GIFs  Tenor
  • Thank you so much @emmasemm. That was really informative. I believe they are going to be placing me on antibiotics because they will likely have to go through an endometrioma or two for my ER and they are worried about infection. They are planning on trying to do a fresh transfer if possible.
  • I took antibiotics prior to my ER but it's standard protocol at my RE's office.  Is this not the normal?
    Me:37 MH:37
    TTGP since 07/2017
    **TW** in spoiler
    DX: PCOS, anovulatory, AMA
    Femara X3: no response
    Clomid X3: BFN (cyst and thin lining)
    IUI (Dec '18) MMC
    IVF (April '19) 9 retrieved, 7 fertilized, 2 normal PGT-A
    FET 06/12/19 - BFP! EDD 02/27/20




  • @celticknotfire it’s not completely standard for ER no, as some practices are worried about antibiotic resistance so don’t prescribe them prophylacticly. But there are many practices I know who do it - so it’s not rare for ER either. As they puncture the wall of the vagina and puncture each follicle there is a minor risk of infection with an ER. 
    It is more rare in an FET cycle - there nothing is punctured, but of course they are putting a catheter into your uterus which could introduce bacteria if it’s not completely sterile - which it should absolutely be!
    Me 43 DH 45
    Married 12/2016
    TTC #1 since 04/2015
    AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
    7 retrievals, 3 transfers
    Jun19 FET BFP, due date 7th March 2020, DD born Feb20
    Sep17 IVF1 - 1ER, 1F, 1ET, BFN
    Nov17 IVF2 - 1ER, 0F
    Jan18 IVF3 - 3ER, 1F, 1ET, BFN
    Feb18 - second opinion and additional testing
    Apr18 IVF4 - cancelled (E2 too high)
    May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
    Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
    Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
    Aug/Sep18 IVF7 - cancelled (cyst)
    Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
    Oct18 IVF8 - Cancelled (cyst and too low TSH)
    Oct18-Jan19 bringing TSH under control
    Feb19 ERA and hysteroscopy
    Mar19 Investigation for fibroid and adenomyosis
    Apr19 adenomyosis confirmed, polyps removed
    Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
    Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN
    Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
    Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
    May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
    Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
    Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
    Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality 

    Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return

  • @emmasemm thanks!  When they were going over all the meds it made perfect sense to me to take it as a prophylactic and it wasn't a strong antibiotic or a large dose.  
    Me:37 MH:37
    TTGP since 07/2017
    **TW** in spoiler
    DX: PCOS, anovulatory, AMA
    Femara X3: no response
    Clomid X3: BFN (cyst and thin lining)
    IUI (Dec '18) MMC
    IVF (April '19) 9 retrieved, 7 fertilized, 2 normal PGT-A
    FET 06/12/19 - BFP! EDD 02/27/20




  • @inthewoods23 That is a great number! Fingers crossed for you that everything goes absolutely perfectly!
  • @inthewoods23 hooray for the all-clear!
    @littleredm that's awful about the fridge!  WTF, universe? 
    @celticknotfire I think it's a basic SA. DH can't go until next week though, I guess the lab is closed for a few days. Glad you are moving forward! (All these meds you ladies are mentioning are making my head spin!)
    @begging4abump thank you for reminding me that I am not alone. Hope your DH gets his SA done, I know that's been a struggle.
    @jennifer_louise I'm sorry to find you over here too, friend. 💚 Not summer for me yet...8 more days left of school, though! Hope your H listens and starts on his vitamins (seriously, what is it with men and vitamins?)
    @keikilove and @emmasemm you ladies are amazing with all your knowledge! 

    Thank you ladies for all your answers, advice, and kind words. 💚 I am still trying to wrap my mind around all this. "Overwhelmed" is an understatement.  No results yet, I think they are waiting to have all the tests done before meeting again to go over results and treatment options. 
    I go in for CD3 blood work tomorrow morning, but have to postpone the saline ultrasound until next cycle. It's the last full week of school so any time off isn't really possible. 
  • [lurking]
    @emmasemm @littleredm @keikilove Re: Neupogen - there was a recent study done on a G-CSF drug referred to by the study as NT100 (Neupogen is a brand of G-CSF drug) to determine if administering G-CSF to women with recurrent loss reduced miscarriage rates. It apparently did not reduce mc’s (earlier, smaller studies had been encouraging I think). However it also did not increase mc rates or other bad outcome rates. Summary here: https://www.miscarriageassociation.org.uk/research/the-response-trial/
  • @MNturnsVA sorry to see you back so soon. ❤

    @inthwoods23 omg what an adventure! Lol my mom always carried facial type wipes everywhere she went.  You never know when you might need to freshen up / inject yourself in a tent!!! 😂  great job.
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