Calling all my RPL friends!!! Who here has seen a reproductive immunologist? From what I have gathered there are four worth seeing in the states. I’m trying to decide which to go with- Kwak Kim, Aimee, Braverman, or Alan Beer. Anyone have any comments on any of these doctors?
Short back story- TTC 4 year’s, 6 pregnancies all miscarried. Mostly male factor with minor Endo recently discovered ( and right tube removed). For reference, we are located in Las Vegas and should have IVF coverage and will see Dr Sher for IVF.
TTC #1 since September 2014Diagnoses: RPL, Endometriosis, MFI
(count, morph, DNI, DNAS, multiple bilateral subclinical varicoceles), low
progesterone
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Loss History (TW):
BFP: 3 May 2015, loss confirmed 4 June 2015
BFP: 15 August 2015, loss confirmed 23 August 2015
BFP: 16 November 2015, loss confirmed 22 November 2015
BFP: 18 July 2016, loss confirmed same day
BFP: 04 March 2018, loss confirmed 23 March 2018
BFP: 12 June 2018, TWINS; D&C 06 July 2018
TTC History (TW):
3 losses in 2015
Met with OBGYN in January 2016
Me: all clear, H: OAT
November 2016: HSG = All
Clear!
January 2017: H tested again, High DNA fragmentation and stainability
February 2017: Clomid + TI + Progesterone = BFN
March 2017: Clomid + HCG + IUI + Progesterone = SA/wash: zero count on attempt
#1, <1,000 on attempt #2= BFN
Varicocele Embolization- 5 May 17
December 2017 SA: Zero improvement after embolization
January IVF- 25 retrieved, 11 mature, 8 fertilized, 3 frozen day fives (3AA, 3AA, 3AA), 1 frozen day 6 (5BB), 1 frozen day 7 (3CC)
Three PGS normal (3AA, 3AA, 5BB), one inconclusive (3AA)
FET #1: 27 February 2018, 3AA & 5BB, one stuck! BFP 04 March 2018.... Loss confirmed 23 March 2018
May 2018: SHG/SIS = all clear "beautiful uterus"
FET #2: 04 June 2018, 3AA PGS normal embryo, 3AA PGS hatching inconclusive embryo.
BFP: 12 June 2018, EDD 20 February 2019
Ultrasound, 25 June 2018: There are two!
Lost Baby A 02 July 2018
Baby B not growing, D&C 06 July 2018
Laparoscopy, hysteroscopy, chromotubation: 23 July 2018: blocked right tube, heavily inflamed, covered in endo. Removed right tube. Removed more endo from uterus, tubes, ovaries. Endo remains on bladder and bowel.
Next Up:
TTC Naturally, possibly IUIs for remainder of 2018.
ER#2 ~Jan 2019
Re: Reproductive immunologists? (with TW)
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!
dx: PCOS, low progesterone; 2 MMC
Sept FET 2018 Spreadsheet
Jan 2 2018 - 1st IVF cycle - 9 retrieved, 7 mature/fertilized, 1 5d transfer + 5 untested snowbabies
Jan 19 2018 - Fresh Transfer #1 one 5dt; BFP 1/25/2018; EDD 10/7/2018; MMC at 8w3d; D&C 3/6/2018
May 16 2018 - FET #1 one 5dt; BFP with 4 betas (6.5, 24.3, 165.5, 2250) - EDD 2/1/2019; MMC at 6w; D&C 6/20/18
Sept 17 2018 - FET #2 one 5dt; BFP 38.9 7dpt, 167 9dpt - EDD 6/5/2019
(3 untested embryos remain)
Diagnoses: RPL, Endometriosis, MFI (count, morph, DNI, DNAS, multiple bilateral subclinical varicoceles), low progesterone
Check out my Infertility blog
Check out my Infertility Instagram
BFP: 15 August 2015, loss confirmed 23 August 2015
BFP: 16 November 2015, loss confirmed 22 November 2015
BFP: 18 July 2016, loss confirmed same day
BFP: 04 March 2018, loss confirmed 23 March 2018
BFP: 12 June 2018, TWINS; D&C 06 July 2018
Met with OBGYN in January 2016
Me: all clear, H: OAT
November 2016: HSG = All Clear!
January 2017: H tested again, High DNA fragmentation and stainability
February 2017: Clomid + TI + Progesterone = BFN
March 2017: Clomid + HCG + IUI + Progesterone = SA/wash: zero count on attempt #1, <1,000 on attempt #2= BFN
Varicocele Embolization- 5 May 17
December 2017 SA: Zero improvement after embolization
January IVF- 25 retrieved, 11 mature, 8 fertilized, 3 frozen day fives (3AA, 3AA, 3AA), 1 frozen day 6 (5BB), 1 frozen day 7 (3CC)
Three PGS normal (3AA, 3AA, 5BB), one inconclusive (3AA)
FET #1: 27 February 2018, 3AA & 5BB, one stuck! BFP 04 March 2018.... Loss confirmed 23 March 2018
May 2018: SHG/SIS = all clear "beautiful uterus"
FET #2: 04 June 2018, 3AA PGS normal embryo, 3AA PGS hatching inconclusive embryo.
BFP: 12 June 2018, EDD 20 February 2019
Ultrasound, 25 June 2018: There are two!
Lost Baby A 02 July 2018
Baby B not growing, D&C 06 July 2018
Laparoscopy, hysteroscopy, chromotubation: 23 July 2018: blocked right tube, heavily inflamed, covered in endo. Removed right tube. Removed more endo from uterus, tubes, ovaries. Endo remains on bladder and bowel.
ER#2 ~Jan 2019
Anyway, I love the smallness of his practice. He’s the only RE so he does all your scans, retrievals, and transfers. He calls you with updates on fertilization and beta results. His staff is small so you get to know all the nurses and even their contracted anesthesiologists. I don’t know what it’s like at other places but I hear that there are often techs who do the scans and you don’t get immediate feedback.
The only things id counsel on are that Dr. Fisch usually takes a more “slow” / less aggressive approach, so if you want to move faster, you have to ask. For example, although I had six IUIs covered I didn’t want to keep wasting cycles trying after my fourth attempt. I think he would have been content exhausting those before moving to IVF. After my second MC, I felt strongly about being tested for clotting factors. I had to ask bc I didn’t think he was going to offer. He’s never denied my requests but I sometimes wish I didn’t have to advocate as hard. But I think that’s true of health care generally.
The only other issue is that they limit the number of women who IVF/FET cycle each month. Don’t know the max but think it’s somewhere around 30 / month. I’ve never had a problem getting booked for a spot but they try to do all retrievals on the same weekend and transfers the following week. I need medicated FET but I presume they may also for natural FET.
Happy to answer anything else if you have other specific questions.
dx: PCOS, low progesterone; 2 MMC
Sept FET 2018 Spreadsheet
Jan 2 2018 - 1st IVF cycle - 9 retrieved, 7 mature/fertilized, 1 5d transfer + 5 untested snowbabies
Jan 19 2018 - Fresh Transfer #1 one 5dt; BFP 1/25/2018; EDD 10/7/2018; MMC at 8w3d; D&C 3/6/2018
May 16 2018 - FET #1 one 5dt; BFP with 4 betas (6.5, 24.3, 165.5, 2250) - EDD 2/1/2019; MMC at 6w; D&C 6/20/18
Sept 17 2018 - FET #2 one 5dt; BFP 38.9 7dpt, 167 9dpt - EDD 6/5/2019
(3 untested embryos remain)