This is a thread where anyone can feel free to request a chart stalk, second-guess FF's interpretation, or post TTC-related questions, regardless of where in your cycle you are. Sometimes FF is wrong. That's where we come in. Get your second opinion here!
Starting us off selfishly today to ask about AFC and FSH. I had my baseline ultrasound and blood work today on cd4. The RE was surprised at my AFC because it was around 6-8, which she said is really unusual for someone my age (30). (ETA: She said they like to see at least 10.) My blood work all came back normal, except for FSH which was just slightly elevated at 9.2. The RE wasn't concerned about it and said it was borderline. I was anxiously awaiting the AMH results all day to find out they combined them with some other blood work they sent me to Quest for, so I did not get those results today, unfortunately. It may be a couple of days to 2 weeks before I get them since they were grouped with my karyotype and RPL labs. So for my question, is that AFC result really worrisome or does it vary per cycle? There's probably not much that anyone can tell me until I get the AMH results, but I googled low AFC today and now I'm kind of going into a tailspin wondering if all of my good eggs are gone. My next appointment with the RE isn't for 2 weeks until all my lab results are back, so I was hoping to get some wisdom/reassurance from some of you that have more experience with AFC numbers. Thank you!
@offtoneverland No super good advice, just support. ((Hugs)) waiting is nerve racking. I log into my patient portal at least 2-3 times a day to look for results. My AFC changed. When it was first done a while back, it was 6-8. At the beginning of my IUI cycle, it was 10. I’m not sure how huge of a differn for that is in reproduction world. Have you read ISWTE? I also hit the 3-4onth mark between those AFCs with CoQ10/Ubiqunol, Vitamin d3 supplement, & serious elimination of bpa/phthalate/synthetics. Coincidence? Correlation? Idk.
@jrm_14 Thank you, friend. That's good to know about your AFC and all the changes you had made leading up to the increase in number. I haven't read ISWTE but I know I need to. I've been scared to start it, TBH, because I don't want to have to change everything in my life while TTC. But I know that's a silly thing to say because *nobody* wants to find themselves in the place where they have to start making so many big changes. It sucks that it doesn't come easy and I guess I haven't been ready to admit that maybe there's a problem. I also wasn't expecting my eggs to be an issue since I'm young, so that caught me way off guard! I'll just be over here twiddling my thumbs waiting for my AMH results. And I had an Amazon gift card from Christmas still, so I'm going to use it right now to guy buy ISWTE! ETA: Oh, and about CoQ10-- **TW** I started taking it right after my 3rd loss, so about a month ago now. **end TW** But the RE seemed skeptical of it and said she asks her patients to stop using it before they start any treatment, so I stopped taking it after that. Perhaps I'll start it up again jic.
@offtoneverland I am sorry about the low AFC. I do think you’ll need to see what the AMH is to get an idea of whether you may have premature DOR. Unfortunately it is possible and DOR might explain the RPL. I agree to look at ISTWE. Most of the changes aren’t that extreme - I find the dietary stuff most challenging and I’m not perfect at it but I feel like steps in the right direction are always good. That is kind of strange to me that your RE is anti CoQ10 - I told my RE I was taking it at our first appt and she was like - great, I want you on twice as much.
@offtoneverland, I’m so sorry you’re stuck in limbo waiting for that AMH number. *hugs* I agree that reading ISWTE is a good idea, even if you’re only able to implement some of the advice in it right now. I initially felt the same way about not wanting to have to change my entire life for TTC, but once I started with the RE it really helped me to have some more concrete things to do while I waited on other results/appointments.
I am also really surprised your RE is anti-CoQ10! My RE didn’t say anything either way when I said I was taking it, but I’ve seen it recommended a lot of places...
@Augusta108@zamora_spin Thank you so much. You guys are the best and I appreciate the moral support. I'll start reading ISWTE tomorrow! I think I'll continue taking CoQ10 for the time being too...you never know what might help!
@offtoneverland firstly, big hugs. Second I recommend a deep breath.
Then please remember not to confuse egg quantity with egg quality.
Quality is mostly dependent on age - unless you have a genetic issue or have had exposure to damaging chemicals/radiation - eg working in a chemical factory or chemotherapy for example. So assuming neither of those applies, then you being only 30yo is a big plus. However many eggs you have, the percentage which are “good” eggs should still be high. Good meaning euploid in this case.
Quantity is a different ballgame. Everyone is born with a different number of eggs, and everyone has different numbers either be released or die off every month. And this can change through your life. And it can vary from month to month.
FSH is a rough indicator of how you might respond to injectibles during stimulation more than anything, from most of the research I’ve done. If it’s already very high, adding more doesn’t have the same effect as if it is naturally low. A very very high FSH also is one of the markers they take to diagnose peri-menopause and menopause. But your FSH on CD4 is within what most accept as a normal range. Yay!!!!! However I would advise to see what it is over a few months - the highest day 2/3/4 value is the one they normally refer to. Also my advice is to use FSH only with AFC and AMH - and to have an eye on the estradiol value too.
AMH is supposed to show a better egg reserve indication as it is measuring what all the remaining undeveloped follicles are “emitting” - the more left, the more is detected. However!!! Like all hormones it can be affected by other things. There is a known relationship that vitamin D levels interfere with AMH levels - too low vit D and AMH is suppressed. Supposedly without suppression AMH only goes down over time, but especially when you have low AMH this seems to not always hold true (changes might be +/- 20% but only +/- 0.2, which might be within the tolerance of a labs results). Ladies in menopause have undetectable AMH.
AFC is really interesting. There is typically a correlation between lower AFC and lower AMH. But the correlation is not perfect. It’s not like a mathematical equation between these two factors - there are certainly a LOT of other factors in the equation, some of them with a huge multiplier. AFC can definitely vary month to month. There is evidence that if estradiol is high at the start of the new cycle then the AFC might be lower than in other cycles. Also cysts can sometimes be seen together with a lower AFC (especially if functional cysts). Finally AFC depends heavily on the TVUS equipment used and on the skill of the person doing the scan! (See @kristokekerooni’s post in the IF thread yesterday). Also if you have a lot of follies they might be hiding behind each other and not all visible at the same time. Remember true Antral follicles are super super tiny!
There is a LOT more I could write, but I think I might bore everyone. If you want to chat more feel free to PM me too.
Me 43 DH 45 Married 12/2016 TTC #1 since 04/2015 AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis 7 retrievals, 3 transfers
Jun19 FET BFP, due date 7th March 2020, DD born Feb20
Sep17 IVF1 - 1ER, 1F, 1ET, BFN Nov17 IVF2 - 1ER, 0F Jan18 IVF3 - 3ER, 1F, 1ET, BFN Feb18 - second opinion and additional testing Apr18 IVF4 - cancelled (E2 too high) May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality) Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality) Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality) Aug/Sep18 IVF7 - cancelled (cyst) Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality) Oct18 IVF8 - Cancelled (cyst and too low TSH) Oct18-Jan19 bringing TSH under control Feb19 ERA and hysteroscopy Mar19 Investigation for fibroid and adenomyosis Apr19 adenomyosis confirmed, polyps removed Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality
Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return
@offtoneverland You've already received great advice and info, but I just wanted to add my data on AFC. I've had it checked three times, once at the start of each IUI. It was 11 the first time, 21 the second, and 16 the third, with no major changes to supplements or diet during that time. So there is definitely variability!
+1 to what @zamora_spin & @kristah2 said. @emmasemm you need to write the dummy's guide to infertility! You are such a wealth of knowledge and quite amazing I always appreciate the amount of time you take to explain and share that information with us. @offtoneverland I have no advise to give but *hugs* waiting sucks!
BFP 3/21/2020! OMG We're having TWINS! 4/17/2020 -------------------------------- LO arrived 11/9/2018! We have a baby! -------------------------------- Me: 33 | DH: 41 Married: March 2016 TTC #1/IUD out January 2017 PCOS dx January 2018 Medicated cycle 2.5mg Letrozole CD3-7 February 2018 BFP 3/10/2018! -------------------------------
TTGP December Siggy Co-Winner: Favorite Moments from Holiday Movies/TV
I know this has been asked before, but I have tried searching old threads and I can't find it. What PNVs do you all recommend? I'm about to run out of mine and I want to change to a kind with DHA. I just wanted to finish off what I had first because I hate being wasteful. Is there anything I need to make sure is included in them? Iron? Calcium? I did try google, but it was overwhelming so I'm hoping you guys can help me.
@acciocoffee I have been taking Megafood Baby & Me (has Iron and folate and is real food based) for almost a year now plus DHA separately. However, I'm about to switch to Zahler +DHA and I'm very excited about that. The Zahler includes Iron and 1000mg of Folate (as opposed to folic acid - folate is more bio-available). This change is going to reduce costs a little since I was buying separate DHA, AND, I will be getting in two pills what I was getting in 5 so... I'm more excited than I should be about vitamins
Has anyone heard of taking choline during pregnancy? Supposedly it's important for brain development and that you should be taking 550 mg a day. I haven't done a ton of research myself but a friend of mine recently started a business selling it and is saying that research is showing that it's important. Apparently we can all benefit from having more in our diet so I started taking some (not hers, too expensive ) Most prenatal vitamins I've looked at have little or no choline in them, so I'm not sure what to think.
Me: 35 H: 35 Married: 4/5/13 "You know that place between sleep and awake, that place where you can still remember dreaming? That's where I will always love you. That's where I'll be waiting." ~Peter Pan
*TW*
BFP #1: 11/12/12 EDD 7/25/13 Baby boy: 7/27/13 BFP #2: 10/29/17 MMC dx @ 9 weeks BFP #3: 2/2/18 MC 2/7/18 BFP #4: 3/2/18 MC 3/9/18 RPL testing and hysteroscopy: all normal BFP #5: 4/1/18 MMC dx @ 14 weeks ----> genetically normal girl Hysteroscopy to remove scar tissue 9/28 BFP #6 11/5/18 EDD 7/20/19 Rainbow baby girl born 7/23/19 BFP #7 12/8/2021 EDD 8/22/2022
@emmasemm You are the best. Seriously. Thank you for being so willing to share your knowledge with others. I agree that you need to write a Fertility for Dummies book. You have this wonderful way of explaining things in a very scientific manner, yet it's incredibly easy to understand. It was super helpful of you to explain how the follicles are measured and all of the other underlying factors. When I googled low AFC, it immediately returned results about early onset menopause and all these other scary things, so I was immediately freaked out. Thank you for talking me off a ledge and helping me see things more clearly. @darkstar42 That is really interesting about your AFC numbers fluctuating. Thank you for sharing that with me! @zamora_spin I started taking Zahler Prenatals after you recommended them a couple of weeks ago. I really like them them! Although *TMI* they make my urine bright fluorescent yellow all day long. I sometimes get nauseous after taking vitamins, but haven't had that problem with these.
@offtoneverland I’m so pleased you found it useful and it helped calm your fears, even if just a little. I’m watching out for when you get your AMH results to see how the picture comes together. And any time you feel like freaking out, just PM me.
Me 43 DH 45 Married 12/2016 TTC #1 since 04/2015 AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis 7 retrievals, 3 transfers
Jun19 FET BFP, due date 7th March 2020, DD born Feb20
Sep17 IVF1 - 1ER, 1F, 1ET, BFN Nov17 IVF2 - 1ER, 0F Jan18 IVF3 - 3ER, 1F, 1ET, BFN Feb18 - second opinion and additional testing Apr18 IVF4 - cancelled (E2 too high) May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality) Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality) Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality) Aug/Sep18 IVF7 - cancelled (cyst) Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality) Oct18 IVF8 - Cancelled (cyst and too low TSH) Oct18-Jan19 bringing TSH under control Feb19 ERA and hysteroscopy Mar19 Investigation for fibroid and adenomyosis Apr19 adenomyosis confirmed, polyps removed Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
Sep17 - Pergoveris 10-17 Sep, Orgalutran 15-18 Sep, Ovitrelle 18 Sep, ER 20 Sep for 2 follies, 1 mature egg, fertilized, ET 1x 2d 4-cell embryo 22/09, 05/10 BFN Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality
Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return
@coco2787 I'm not an expert at vitamins nor do I know anything about choline, but I figure if it really were vital to brain development it would be included in most prenatals. That said, mine (Zahler with DHA) contains 25mg of choline.
I work in a research lab with lots and lots of hazardous
chemicals. Most of the work I do is
under a fume hood and/or has some sort of exhaust system hooked up to it, but occasionally,
like once a week, I do have to take chemicals out of the fume hood for brief
amounts of time (5-10 min). I know that
I will need to take extra precaution once I get KU but after talking to a
coworker today I’m wondering if I need to be taking the extra precaution now
while TTC… I know the exposure isn’t a whole lot but I’m freaking out. Have I
been ruining our chances this whole time? What do I do? I can’t just stop
working, and my boss just told me yesterday that he wants me to be spending
more time in the lab and less time at my desk…
*TW* TTC history
Me:32 DH:31 Married: 8/2015
TTC #1: 4/2017 Testing: HSG, U/S, BW, and DH's SA all normal DX: Unexplained 8/2018: Clomid + TI = BFN 9/2018: Clomid + TI + Progesterone = BFN 11/2018: Clomid + IUI + Progesterone = BFN 12/2018: Letrozole + IUI + Progesterone \\ Cancelled due to cyst 1/2019: Letrozole + IUI + Progesterone = BFP! \\ EDD Sept 30th, 2019 10/7/2019: Healthy baby boy!
@ljmoon6 I’m sorry, I have no idea whether the chemicals might be affecting. I don’t know enough about those affects.
I’d like to request a CS! I have no idea whether I belong in WTO or TWW right now. On CD18 FF gave me CH for CD15. I moved over to TWW. Yesterday, CD19 it took them away. My temp went back up again this morning CD20, and I tried discarding CD19’s temp because I only got 4 hours of sleep, but it won’t give me back my CH, even if I enter high temps into the future is this another an-O cycle? Disclaimer: I have no thyroid so my BBT is unreliable, but FF gave me CH before so I’m worried. Also, the 8 days in a row High fertility blinking smiley.
Me: 28 DH: 29 Married since 2012 dating since 2005. Golden Retriever girls (8) and (3), orange feral rescue tabby (1).
Finally TTC#1 as of 11/2017! Thryoidectomy 2007, PCOS, disordered proliferative endometrium.
Hi ladies, I'm new and would love some help with my chart this month. A bit about my background, I have been TTC for 6 months now. This is the first month charting temps and using OPK. Thought maybe we would just get lucky before and that didn't happen. This is the longest cycle I have had off BC (month 7 now), they are normally between 29-31. I keep feeling what I think are cramps or at least a small discomfort, but so far no visit from AF and no BFP. The OPK test was positive on CD17 so FF marked O day as CD 18. I'm just confused, please give help/advice!!
Hi ladies, I'm new and would love some help with my chart this month. A bit about my background, I have been TTC for 6 months now. This is the first month charting temps and using OPK. Thought maybe we would just get lucky before and that didn't happen. This is the longest cycle I have had off BC (month 7 now), they are normally between 29-31. I keep feeling what I think are cramps or at least a small discomfort, but so far no visit from AF and no BFP. The OPK test was positive on CD17 so FF marked O day as CD 18. I'm just confused, please give help/advice!!
QFP What exactly are you confused about? You can get a positive opk up to 36 hours before ovulation so 1/16 may not be an accurate O date therefore how many DPO may also not be accurate. Also you were not consistent in tracking temps so 1/16 really is not confirmed. Wait a few more days, retake an HPT if still no AF. Also, please intro in the weekly newbie thread. And welcome, I hope your stay here is short.
ETA: Also, please note that it is against TOU to ask, even in a roundabout way, if your are pregnant. We are not doctors and cannot see into your uterus. Please contact a medical professional if that is what you are asking.
BFP 3/21/2020! OMG We're having TWINS! 4/17/2020 -------------------------------- LO arrived 11/9/2018! We have a baby! -------------------------------- Me: 33 | DH: 41 Married: March 2016 TTC #1/IUD out January 2017 PCOS dx January 2018 Medicated cycle 2.5mg Letrozole CD3-7 February 2018 BFP 3/10/2018! -------------------------------
TTGP December Siggy Co-Winner: Favorite Moments from Holiday Movies/TV
Thank you so much for your response! I wasn't really asking about being pregnant, more about how to understand my chart. With it being my first time TTC and my first month of trying to chart (taking temps at the same time is hard!!!). I'm not sure what to look for, for the actual ovulation date (I missed 3 days because I went out of town and forgot my thermometer). I'm hoping that next month I can be more consistent with my temping to help understand the chart better. Just unsure what to look for signs of ovulation and post ovulation. Thanks again
@boundingpluto Hey there...So what we're the results of your opks after that positive? Did you only have one day of positive and then they went back to negative? If you input those test results (of you have them) it might help FF adjust to a potential O day.
When you get a positive opk, it's crucial to be spot on about temping those next few days. Reason being you can clearly see a temp shift/ovulation by three days of sustained temps. With how many temps you're missing right after the positive opk, it's near impossible to say when you O'd exactly. For example, I get two to three days of positive opks, then a negative, then temp shift usually on that negative day. So if I stopped on the first positive day of opks, I'd never know that....And I'd constantly be thinking AF was late. So you could really only be 12dpo right now...We can't say for sure.
Also, you can have multiple groups of positive opks in one cycle, and never ovulate....So you have to see that temp rise to really know you ovulated, and you can relax. It's cool to not temp in the tww...lots of us do that, but you have to see three high temps in a row before you stop
@boundingpluto have you read the newbie guide yet? There's some great info there regarding ovulation signs. Personally I track my CM (cervical mucus), CP (cervical position), along with using OPKs and temping. A lot right? I hear you on it being a hard temping every day at the same time. It happens. That being said, the fertilityfriend app also has some great information on ovulation signs and explaining temp shift, etc. Also @josie12367 had some awesome information. Thanks Josie! I always struggle to clearly and concisely word these brief overviews aside from "googleit!"
BFP 3/21/2020! OMG We're having TWINS! 4/17/2020 -------------------------------- LO arrived 11/9/2018! We have a baby! -------------------------------- Me: 33 | DH: 41 Married: March 2016 TTC #1/IUD out January 2017 PCOS dx January 2018 Medicated cycle 2.5mg Letrozole CD3-7 February 2018 BFP 3/10/2018! -------------------------------
TTGP December Siggy Co-Winner: Favorite Moments from Holiday Movies/TV
Those of you who take a B-complex- is there one that you recommend?
Me: 35 H: 35 Married: 4/5/13 "You know that place between sleep and awake, that place where you can still remember dreaming? That's where I will always love you. That's where I'll be waiting." ~Peter Pan
*TW*
BFP #1: 11/12/12 EDD 7/25/13 Baby boy: 7/27/13 BFP #2: 10/29/17 MMC dx @ 9 weeks BFP #3: 2/2/18 MC 2/7/18 BFP #4: 3/2/18 MC 3/9/18 RPL testing and hysteroscopy: all normal BFP #5: 4/1/18 MMC dx @ 14 weeks ----> genetically normal girl Hysteroscopy to remove scar tissue 9/28 BFP #6 11/5/18 EDD 7/20/19 Rainbow baby girl born 7/23/19 BFP #7 12/8/2021 EDD 8/22/2022
@coco2787 - I’ve only tried one, but I take the one from rainbow light. I haven’t done a full analysis on ingredient safety yet, but I like it because it’s food based. It does turn your pee highlighter yellow, though. https://www.rainbowlight.com/complete-b-complex.html
Re: Chart Stalk/Questions w/o 1/29
So for my question, is that AFC result really worrisome or does it vary per cycle? There's probably not much that anyone can tell me until I get the AMH results, but I googled low AFC today and now I'm kind of going into a tailspin wondering if all of my good eggs are gone. My next appointment with the RE isn't for 2 weeks until all my lab results are back, so I was hoping to get some wisdom/reassurance from some of you that have more experience with AFC numbers. Thank you!
DD1: 8/2014
TTC #2: 6/2017
BFP 8/3/2017 | CP 8/4
BFP 10/16/2017 | CP 10/21
BFP 12/18/2017 | CP 12/28
BFP 2/15/2018 | EDD: November 2nd | It's a girl!
DD2: 10/2018
I'll just be over here twiddling my thumbs waiting for my AMH results. And I had an Amazon gift card from Christmas still, so I'm going to use it right now to guy buy ISWTE!
ETA: Oh, and about CoQ10-- **TW** I started taking it right after my 3rd loss, so about a month ago now. **end TW** But the RE seemed skeptical of it and said she asks her patients to stop using it before they start any treatment, so I stopped taking it after that. Perhaps I'll start it up again jic.
DD1: 8/2014
TTC #2: 6/2017
BFP 8/3/2017 | CP 8/4
BFP 10/16/2017 | CP 10/21
BFP 12/18/2017 | CP 12/28
BFP 2/15/2018 | EDD: November 2nd | It's a girl!
DD2: 10/2018
I am also really surprised your RE is anti-CoQ10! My RE didn’t say anything either way when I said I was taking it, but I’ve seen it recommended a lot of places...
DD1: 8/2014
TTC #2: 6/2017
BFP 8/3/2017 | CP 8/4
BFP 10/16/2017 | CP 10/21
BFP 12/18/2017 | CP 12/28
BFP 2/15/2018 | EDD: November 2nd | It's a girl!
DD2: 10/2018
Then please remember not to confuse egg quantity with egg quality.
Quality is mostly dependent on age - unless you have a genetic issue or have had exposure to damaging chemicals/radiation - eg working in a chemical factory or chemotherapy for example. So assuming neither of those applies, then you being only 30yo is a big plus. However many eggs you have, the percentage which are “good” eggs should still be high. Good meaning euploid in this case.
Quantity is a different ballgame. Everyone is born with a different number of eggs, and everyone has different numbers either be released or die off every month. And this can change through your life. And it can vary from month to month.
FSH is a rough indicator of how you might respond to injectibles during stimulation more than anything, from most of the research I’ve done. If it’s already very high, adding more doesn’t have the same effect as if it is naturally low. A very very high FSH also is one of the markers they take to diagnose peri-menopause and menopause. But your FSH on CD4 is within what most accept as a normal range. Yay!!!!! However I would advise to see what it is over a few months - the highest day 2/3/4 value is the one they normally refer to. Also my advice is to use FSH only with AFC and AMH - and to have an eye on the estradiol value too.
AMH is supposed to show a better egg reserve indication as it is measuring what all the remaining undeveloped follicles are “emitting” - the more left, the more is detected. However!!! Like all hormones it can be affected by other things. There is a known relationship that vitamin D levels interfere with AMH levels - too low vit D and AMH is suppressed. Supposedly without suppression AMH only goes down over time, but especially when you have low AMH this seems to not always hold true (changes might be +/- 20% but only +/- 0.2, which might be within the tolerance of a labs results). Ladies in menopause have undetectable AMH.
AFC is really interesting. There is typically a correlation between lower AFC and lower AMH. But the correlation is not perfect. It’s not like a mathematical equation between these two factors - there are certainly a LOT of other factors in the equation, some of them with a huge multiplier. AFC can definitely vary month to month. There is evidence that if estradiol is high at the start of the new cycle then the AFC might be lower than in other cycles. Also cysts can sometimes be seen together with a lower AFC (especially if functional cysts).
Finally AFC depends heavily on the TVUS equipment used and on the skill of the person doing the scan! (See @kristokekerooni’s post in the IF thread yesterday). Also if you have a lot of follies they might be hiding behind each other and not all visible at the same time. Remember true Antral follicles are super super tiny!
There is a LOT more I could write, but I think I might bore everyone. If you want to chat more feel free to PM me too.
Married 12/2016
TTC #1 since 04/2015
AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
7 retrievals, 3 transfers
Nov17 IVF2 - 1ER, 0F
Jan18 IVF3 - 3ER, 1F, 1ET, BFN
Feb18 - second opinion and additional testing
Apr18 IVF4 - cancelled (E2 too high)
May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
Aug/Sep18 IVF7 - cancelled (cyst)
Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
Oct18 IVF8 - Cancelled (cyst and too low TSH)
Oct18-Jan19 bringing TSH under control
Feb19 ERA and hysteroscopy
Mar19 Investigation for fibroid and adenomyosis
Apr19 adenomyosis confirmed, polyps removed
Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality
Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return
@offtoneverland I have no advise to give but *hugs* waiting sucks!
--------------------------------
LO arrived 11/9/2018! We have a baby!
--------------------------------
Me: 33 | DH: 41
Married: March 2016
TTC #1/IUD out January 2017
PCOS dx January 2018
Medicated cycle 2.5mg Letrozole CD3-7 February 2018
BFP 3/10/2018!
-------------------------------
Married: 08/2016
TTC: 10/2017
IUI #1-3 BFN
IVF 11/2018- 23 eggs retrieved, 16 mature, 14 fertilized with ICSI with 7 embryos making it to freeze
FET #1 02/2019 BFN
FET #2 4/19 BFP!!!!! EDD 1/4/20
TTC #2 - August 2016
MFI
IUI #1-3 BFN
BFP 4/21/18 MMC 6/11/18
This is the one I just ordered - it’s the #1 recommended for egg quality
TTC #2 - August 2016
MFI
IUI #1-3 BFN
BFP 4/21/18 MMC 6/11/18
Married: 4/5/13
"You know that place between sleep and awake,
that place where you can still remember dreaming?
That's where I will always love you.
That's where I'll be waiting."
~Peter Pan
*TW*
BFP #2: 10/29/17 MMC dx @ 9 weeks
BFP #3: 2/2/18 MC 2/7/18
BFP #4: 3/2/18 MC 3/9/18
RPL testing and hysteroscopy: all normal
BFP #5: 4/1/18 MMC dx @ 14 weeks ----> genetically normal girl
Hysteroscopy to remove scar tissue 9/28
BFP #6 11/5/18 EDD 7/20/19 Rainbow baby girl born 7/23/19
BFP #7 12/8/2021 EDD 8/22/2022
@darkstar42 That is really interesting about your AFC numbers fluctuating. Thank you for sharing that with me!
@zamora_spin I started taking Zahler Prenatals after you recommended them a couple of weeks ago. I really like them them! Although *TMI* they make my urine bright fluorescent yellow all day long. I sometimes get nauseous after taking vitamins, but haven't had that problem with these.
DD1: 8/2014
TTC #2: 6/2017
BFP 8/3/2017 | CP 8/4
BFP 10/16/2017 | CP 10/21
BFP 12/18/2017 | CP 12/28
BFP 2/15/2018 | EDD: November 2nd | It's a girl!
DD2: 10/2018
I’m watching out for when you get your AMH results to see how the picture comes together.
And any time you feel like freaking out, just PM me.
@zamora_spin @kristah2 @lurvleybunchococonuts thanks for the love
Married 12/2016
TTC #1 since 04/2015
AMA, DOR (AMH 0.65, AFC 2-4) and autoimmune issues (RA, APS), low TSH, adenomyosis
7 retrievals, 3 transfers
Nov17 IVF2 - 1ER, 0F
Jan18 IVF3 - 3ER, 1F, 1ET, BFN
Feb18 - second opinion and additional testing
Apr18 IVF4 - cancelled (E2 too high)
May/Jun18 IVF4 - 4ER, 0M, 1F, 1 frozen day 3 (not best quality)
Jun/Jul18 IVF5 - 5 ER, 3M, 2F, 2 frozen day 3 (not best quality)
Jul/Aug18 IVF6 - 4ER, 3M, 2F, 2 frozen day 3 (good quality)
Aug/Sep18 IVF7 - cancelled (cyst)
Sep/Oct18 IVF7 - 3ER, 3M, 2F, 2 frozen Day 3 (excellent quality)
Oct18 IVF8 - Cancelled (cyst and too low TSH)
Oct18-Jan19 bringing TSH under control
Feb19 ERA and hysteroscopy
Mar19 Investigation for fibroid and adenomyosis
Apr19 adenomyosis confirmed, polyps removed
Jun19 FET after 2 months Lupron, autoimmune protocol, transferred two day 3 frozen embryos
Nov17 IVF2 - Pergoveris 2-14 Nov, Orgalutran 5-14 Nov, Ovitrelle 15 Nov, ER 17 Nov for 3 follies, 1 mature egg, did not fertilize
Jan18 IVF3 - Pergoveris 30 Dec - 8 Jan, Orgalutran 5-8 Jan, Ovitrelle 9 Jan, ER 11 Jan 3 eggs, 2 mature, 1 fertilized, ET 1x 4d 12-cell embryo 15/01, 24/01 BFN
May/Jun18 IVF4 - Rekovelle 25-29 May, Menogon 30May - 2Jun, Zomacton 25 27 29 31 May and 2Jun, Cetrotide 30May - 3Jun, Gonasi 3Jun, ER 5Jun 4 eggs, none mature, two matured overnight, 1 fertilized with ICSI, Frozen day 3 but not good quality
Jun/Jul18 IVF5 - Rekovelle 21-24 June, Menogon 25Jun-3Jul, Puregon 4-5Jul, Zomacton 21 23 25 27 29 Jun, Cetrotide 25Jun-5Jul, Gonasi 6Jul, ER 8Jul 5 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 but not good quality
Jul/Aug18 IVF6 - Rekovelle 26-29 Jul, Menogon 30Jul-7Aug, Buserelin 26Jul-7Aug, Zomacton 26 28 30 Jul 1 3 Aug, Gonasi 7Aug, ER 9Aug 4 eggs, 3 mature, 2 fertilized (normal IVF), 2 frozen day 3 good quality
Sep/Oct18 IVF7 - Menogon 19-30Sep, Buserelin 19-30Sep, Zomacton 19 21 23 25 27 Sep, Ovitrelle 1 Oct, ER 3 eggs, 3 mature, 2 fertilized with ICSI, 2 frozen day 3 excellent quality
Fav Quote: The greatest thing you'll ever learn is just to love and be loved in return
DD1: 8/2014
TTC #2: 6/2017
BFP 8/3/2017 | CP 8/4
BFP 10/16/2017 | CP 10/21
BFP 12/18/2017 | CP 12/28
BFP 2/15/2018 | EDD: November 2nd | It's a girl!
DD2: 10/2018
Alright. I’m having a freak out moment. Help!
I work in a research lab with lots and lots of hazardous chemicals. Most of the work I do is under a fume hood and/or has some sort of exhaust system hooked up to it, but occasionally, like once a week, I do have to take chemicals out of the fume hood for brief amounts of time (5-10 min). I know that I will need to take extra precaution once I get KU but after talking to a coworker today I’m wondering if I need to be taking the extra precaution now while TTC… I know the exposure isn’t a whole lot but I’m freaking out. Have I been ruining our chances this whole time? What do I do? I can’t just stop working, and my boss just told me yesterday that he wants me to be spending more time in the lab and less time at my desk…
Married: 8/2015
TTC #1: 4/2017
Testing: HSG, U/S, BW, and DH's SA all normal
DX: Unexplained
8/2018: Clomid + TI = BFN
9/2018: Clomid + TI + Progesterone = BFN
11/2018: Clomid + IUI + Progesterone = BFN
12/2018: Letrozole + IUI + Progesterone \\ Cancelled due to cyst
1/2019: Letrozole + IUI + Progesterone = BFP! \\ EDD Sept 30th, 2019
10/7/2019: Healthy baby boy!
TTC #2: 12/2020
2/2021: Letrozole + TI = BFN
3/2021: Letrozole + TI = BFN
4/2021: Surprise! Natural BFP! \\ EDD Jan 6th, 2022 \\ Chemical, betas not rising
8/2021: Letrozole + IUI + Progesterone = BFN
9/2021: Letrozole + IUI + Progesterone = BFN
10/2021: Letrozole + IUI + Progesterone = BFN
11/2021: Letrozole + IUI + Progesterone = BFP! \\ EDD July 29th, 2022
I’d like to request a CS! I have no idea whether I belong in WTO or TWW right now. On CD18 FF gave me CH for CD15. I moved over to TWW. Yesterday, CD19 it took them away. My temp went back up again this morning CD20, and I tried discarding CD19’s temp because I only got 4 hours of sleep, but it won’t give me back my CH, even if I enter high temps into the future is this another an-O cycle? Disclaimer: I have no thyroid so my BBT is unreliable, but FF gave me CH before so I’m worried. Also, the 8 days in a row High fertility blinking smiley.
Married since 2012 dating since 2005.
Golden Retriever girls (8) and (3), orange feral rescue tabby (1).
Finally TTC#1 as of 11/2017!
Thryoidectomy 2007, PCOS, disordered proliferative endometrium.
What exactly are you confused about? You can get a positive opk up to 36 hours before ovulation so 1/16 may not be an accurate O date therefore how many DPO may also not be accurate. Also you were not consistent in tracking temps so 1/16 really is not confirmed. Wait a few more days, retake an HPT if still no AF. Also, please intro in the weekly newbie thread. And welcome, I hope your stay here is short.
ETA: Also, please note that it is against TOU to ask, even in a roundabout way, if your are pregnant. We are not doctors and cannot see into your uterus. Please contact a medical professional if that is what you are asking.
--------------------------------
LO arrived 11/9/2018! We have a baby!
--------------------------------
Me: 33 | DH: 41
Married: March 2016
TTC #1/IUD out January 2017
PCOS dx January 2018
Medicated cycle 2.5mg Letrozole CD3-7 February 2018
BFP 3/10/2018!
-------------------------------
When you get a positive opk, it's crucial to be spot on about temping those next few days. Reason being you can clearly see a temp shift/ovulation by three days of sustained temps. With how many temps you're missing right after the positive opk, it's near impossible to say when you O'd exactly. For example, I get two to three days of positive opks, then a negative, then temp shift usually on that negative day. So if I stopped on the first positive day of opks, I'd never know that....And I'd constantly be thinking AF was late. So you could really only be 12dpo right now...We can't say for sure.
Also, you can have multiple groups of positive opks in one cycle, and never ovulate....So you have to see that temp rise to really know you ovulated, and you can relax. It's cool to not temp in the tww...lots of us do that, but you have to see three high temps in a row before you stop
Good luck!
Also @josie12367 had some awesome information. Thanks Josie! I always struggle to clearly and concisely word these brief overviews aside from "googleit!"
--------------------------------
LO arrived 11/9/2018! We have a baby!
--------------------------------
Me: 33 | DH: 41
Married: March 2016
TTC #1/IUD out January 2017
PCOS dx January 2018
Medicated cycle 2.5mg Letrozole CD3-7 February 2018
BFP 3/10/2018!
-------------------------------
Married: 4/5/13
"You know that place between sleep and awake,
that place where you can still remember dreaming?
That's where I will always love you.
That's where I'll be waiting."
~Peter Pan
*TW*
BFP #2: 10/29/17 MMC dx @ 9 weeks
BFP #3: 2/2/18 MC 2/7/18
BFP #4: 3/2/18 MC 3/9/18
RPL testing and hysteroscopy: all normal
BFP #5: 4/1/18 MMC dx @ 14 weeks ----> genetically normal girl
Hysteroscopy to remove scar tissue 9/28
BFP #6 11/5/18 EDD 7/20/19 Rainbow baby girl born 7/23/19
BFP #7 12/8/2021 EDD 8/22/2022
Married: 2016
BFP #1 4/23/18, blighted ovum 5/29/18
BFP#2 7/14/18, DS 4/5/19