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Gonal-F

tosh24tosh24 member
in Infertility
Hi ladies....wasn't sure where to post this but just looking for anyone who has experience with Gonal-F.

My dx is unexplained and I've had 3 failed IUIs with letrezole. Moving onto my 4th IUI with Gonal-F this time - I start tomorrow.  I know I'll have increased monitoring appointments but just looking for what to expect in terms of side effects or any other tidbits anyone would like to share. The search function didnt return much useful info.  TIA
Me: 35 I DH: 38
*TW loss and children mentioned*
DD:2006 | Dx: Unexplained Secondary Infertility | DS: 2011

TFAS since 2012

Oct 16: Spontaneous BFP | m/c @ 9w1d (massive SCH) | D&C
Apr 17: IUI #1 = BFN
May 17: IUI #2 = BFN
Jun 17: IUI #3 = Late BFP (18 DPO) | NMC 17Jul17 @ ~6w
Aug 17: IUI #4 = Cancelled due to premature ovulation | TI = BFN
Sep 17: IUI #5 = Cancelled due to overstimulation (10+ follies)
Nov 17: IVF #1 = Cancelled due to non-IF related health issue | TI = BFN
Dec 17: IVF #1 = Puregon 200, Menopur 75, Orgalutran, Suprefact trigger due to OHSS risk | 22R, 18M, 16F, 10B frozen  
Feb 18: FET #1 (medicated) = BFN
Mar 18: FET #2 (natural cycle) = CP (beta 1: 54; beta 2: 0)
Apr 18: FET #3 (natural cycle) = cancelled due to missed ovulation
Apr 18: FET #3 (natural cycle) = BFP! Beta 1: 201  Beta 2: 585 Beta 3: 3254 Beta 4: 9715 U/S 19May - one bean measuring on track with a HB of 125!
EDD: 07Jan2019 Team Green
My Rainbow Baby Boy born 03Jan2019 <3 

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Re: Gonal-F

  • kristimh80kristimh80 member
    I took Follistim which is the same as Gonal-F and had no side effects at all from it. Stomach got a little sore from shots, but that's about it. Last IUI cycle I got 4 follicles from it. :) 
    TTC #1 since April 2015
    June 2016 - CP
    2017 - Medicated Cycles & IUI's
    IVF w/ PGS  - January 2018
    FET #1 - April 2018 - BFN
    ERA Cycle May / June 2018
    ERA Biopsy June 2018 ~ Results: receptive (no change)
    FET #2 - July 2018 - BFP <3 Beta #1 - 137 Beta #2 - 410
    U/S #1 7wk1d - HB 144 U/S #2 9w1d HB 166
    Anatomy Scan 1st 11/2/18 2nd AS 11/19
    EDD March 28, 2019
    Baby Girl born 3/26/19  <3



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  • Worldtravler0522Worldtravler0522 member
    I had pretty much no symptoms from the Gonal. Good luck!

    Me 36 DH 34 - Married May 2010
    DX: PCOS/Unexplained Infertility/MTHFR Mutation
    TTC since December 2014
    Fresh Transfer: Gonal, Menopur, Cetrotide. ~ Chemical Pregnancy :(  
    FET #1: 1st Beta- 3,792~ 2nd Beta- 4,227~ BFP ~ Miscarriage at 8 weeks :( 
    FET #2: 1st Beta 207~2nd Beta 235~ BFP~ Miscarriage at 6 weeks :(
    FET #3: 1st Beta 18~ 2nd Beta 44~BFP~ Miscarriage 5 weeks :(
    FET #4: 1st Beta 50~ 2nd Beta 97.7~ Miscarriage 6 weeks 5 days :(
    FET#5: 1st Beta 29~ 2nd Beta 109~ 3rd Beta 227~ 4th Beta 661~ Miscarriage 5 weeks 3 days 
    Miracle Natural BFP Estimated Due Date June 2019~ God is good 
    2 snow babies 






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  • joneser1281joneser1281 member
    @tosh24 I took Follistim for TI with Ovidrel a little over a year ago.  Then last summer when it was time to do my first IVF cycle, there was a Follistim shortage, so my RE switched me to Gonal-F.  I was actually pretty miserable on both Follistim and Gonal-F, but was taking the Gonal-F along with Menopur for IVF.  I had stomach pains, nausea, vomiting, etc.  However, these issues could have been due to the bowel endo that we didn't know I had at the time... It's likely the drugs were stimulating the lesions, causing more discomfort than usual.  I just wanted to share, since you said your DX is unexplained.  Most likely you'll not have issues like the other ladies who posted, but if you find that you do, it might be a clue to an underlying condition.  FX that it's smooth sailing for you!

    Me: 35 DH: 41, Married since 2009

    TTC since June 2012

    Aug. 2012: CP

    2013 Several cycles of TI with Clomid = BFN

    Feb. 2014: IUI = BFN

    June 2014: IUI w/Clomid = BFN

    Jul. 2014: IUI w/Letrozole = BFN

    Apr. 2016: Consult to begin IVF

    May 2016 TI w/Follistim and Ovidrel = BFN

    Jul. 2016: BCPs, baby aspirin, Vitamin D, COQ10, DHEA, Gonal F, Menopur, Cetrotide, Novarel, Leuprolide Acetate: 21 eggs retrieved, (10 w/ ICSI, 11 w/conv. IVF) 13 fertilized

    Jul. 2016: Endometrin, Fresh Transfer 2AB = CP

    7 frozen

    Oct. 2016: BCPs, baby aspirin, Estradiol, PIO, FET 4AA = CP

    6 frozen

    Nov. 2016: Hospitalized for small bowel obstruction

    Mar. 2017: Diagnostic Laparoscopy = Twist found in intestine - part of small intestine, part of colon, and appendix removed, bowel resection - caused by Endometriosis

    May 2017: 3.75 Lupron Depot

    June 2017: FET postponed due to complex cysts in breasts

    June 2017: Endometrial scratch

    Jul. 2017: Baby aspirin, Estradiol, PIO, FET 4AA (lost 1 4AA in thaw) = CP

    4 frozen

    Sept. 2017: ERA testing

    Oct. 2017: Breast cysts biopsied

    Dec. 2017: FET

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  • SP128SP128 member
    I'm on gonal f now and have been tolerating really well. You just dial up your dose. It's super easy. The needle is small and thin too :smile:
    ***TW***
    Me: 36  DH:35
    Married: 7/10/2016
    TTC#1 - May 2016
    BFP 9/6/2016 - Missed MC 10/20/2016  
    BFP 5/5/2017  - CP
    IVF #1 - June 2017  - Transferred 1 fresh 4 AA embryo.  7/9 Beta #1 - 161 
    <3 Adam <3 Born on 3/18/18




     
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  • tosh24tosh24 member
    Thanks for the responses everyone! I don't feel quite as nervous now :)

    @joneser1281 That sounds awful - sorry you had to go through that. I will definitely keep in tune with my body (how can you not while going through this process!) and seek help if things seem off. Thanks for your advice. 

    Me: 35 I DH: 38
    *TW loss and children mentioned*
    DD:2006 | Dx: Unexplained Secondary Infertility | DS: 2011

    TFAS since 2012

    Oct 16: Spontaneous BFP | m/c @ 9w1d (massive SCH) | D&C
    Apr 17: IUI #1 = BFN
    May 17: IUI #2 = BFN
    Jun 17: IUI #3 = Late BFP (18 DPO) | NMC 17Jul17 @ ~6w
    Aug 17: IUI #4 = Cancelled due to premature ovulation | TI = BFN
    Sep 17: IUI #5 = Cancelled due to overstimulation (10+ follies)
    Nov 17: IVF #1 = Cancelled due to non-IF related health issue | TI = BFN
    Dec 17: IVF #1 = Puregon 200, Menopur 75, Orgalutran, Suprefact trigger due to OHSS risk | 22R, 18M, 16F, 10B frozen  
    Feb 18: FET #1 (medicated) = BFN
    Mar 18: FET #2 (natural cycle) = CP (beta 1: 54; beta 2: 0)
    Apr 18: FET #3 (natural cycle) = cancelled due to missed ovulation
    Apr 18: FET #3 (natural cycle) = BFP! Beta 1: 201  Beta 2: 585 Beta 3: 3254 Beta 4: 9715 U/S 19May - one bean measuring on track with a HB of 125!
    EDD: 07Jan2019 Team Green
    My Rainbow Baby Boy born 03Jan2019 <3 

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  • RMDSJTKRMDSJTK member
    I did 3 rounds IVF each time using gonal f and didn't have any negative side effects and after getting initial fear of giving myself shots found it to be the easiest of all meds/shots
    Report Reply
  • sarajasonivfsarajasonivf member
    I just had my er today and I was on follistim. By far the easiest med to be on. Just some bloating and few bruises on tummy. You will do great 
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