HGH: human growth hormone

Aera11 · June 2017

has anyone used HGH shots during IVF? I don't technically qualify for it but I've done some research & my nurse is going to find updated pricing but it's about $1000/vial (which is only two shots), so it's pricey & not used often but it sounds like it could help. I'm about to start IVF #4 & am hoping this will help with egg quality among other things!

dragonette505 · June 2017

I second this question! I am going to be using this in my next cycle anyway (already purchased) but interested to hear about people's experiences!

JamieH2000 · June 2017

Hi Ladies,

I tried it during my second IVF (estrogen priming and then microdose lupron). It really didn't help me at all, as I only got 2 eggs. My third IVF I was able to get 12 eggs, using estrogen priming and then antagonist, so I think it was just finding the right protocol for me. I think for a few ladies, it can make a difference and is worth trying if you want to spend the $$. For me, it was $1800 for 10 days worth, and I was willing to take the risk.

SP128 · June 2017

deleted post. Read hgh as hcg!!!! Wrote a long post on hcg. Ugh. My brain is mush

dragonette505 · June 2017

@JamieH2000 Thanks for your input! Ive googled and seen it go both ways...some ppl swearing by it and some having worse cycles.... I've even seen some where women thought they had horrible cycles with less eggs but ended up with take home babies... I feel like I've tried so many other things (antagonist w/out estrogen priming, antagonist with estrogen priming, micodose Lupron) I guess its time to try hgh... ive already bought it so for sure I'm trying it at least one cycle....

@SP128 Did you use HCG in an IVF cycle during stimming? (I mean other than for triggering) Just curious now

SP128 · June 2017

@dragonette505 yes hcg from day 1 of stimming. Re increased hcg last friday and decreased gonal f. No clue what the hcg does though. I should be triggering with ovidrel tonight. That is hcg as well right ?

JamieH2000 · June 2017

@sp128- I am pretty sure you used low dose (diluted) HCG (like 10-20 units per day). my old clinic did that instead of adding menopur to the stims. They thought they could control the LH rise better or something I think...

Sugarbreak · June 2017

I used it with my last cycle and don't think it helped. I had fewer eggs and embryos than the previous cycle. However, with the HGH cycle I did have one embryo make it to 5 day blast, whereas the cycle before I had none. I transferred that embryo, got pregnant, but then found out yesterday at 8w1d that there was no heartbeat.

I was the one who had brought it up to my RE. She said she wouldn't have considered it for me; she usually prescribes it to those with very low ovarian reserve. Mine levels were not quite at point, but I wanted to do everything I could since it was my last go of this. She said she'd prescribe it if I wanted, but not to feel bad if I didn't want to through down the cash for it.

Personally, I wouldn't do it again unless my RE highly recommended it.

SP128 · June 2017

@JamieH2000 yup I did use the low dose. Started with 20 then increased to 30

LeFemmeViolette · June 2017

Just wanted to chime in to advocate for the HGH. I went through 2 retrievals- the first one yielded 16 follicles retrieved, but we only ended up with 4 day-5 embryos, and only one of which tested PGS normal.

After that transfer failed, my doctor suggested adding a HGH to my stim regimen. Again, had 16 eggs retrieved, 4 made it to day 5... except this time 3 out of 4 tested PGS normal. Sure, it could be a coincidence, but maybe the HGH did help! As I understand it, it helps with quality rather than quantity.

Hope that helps! : )

[Deleted User] · June 2017

@JamieH2000 My RE is doing the same low-dose hcg protocol with me as @SP128 My nurse seemed to think it helps produce more mature eggs too, not just more follis, so we shall see...

I would just like to mention as well, the caveat my RE told me with whatever protocol, not that i have any experience with hgh or anything else for that matter - but she pretty much tolf me flat out it's a crapshoot every time. Sometimes you can repeat the exact same protocol with the same patient from one cycle to the next, and have a totally different outcome. So unfortunately, the whole thing of changing even just one thing, "that thing" may or may not actually have contributed to the different result, bc there's just so many other factors at play with how your ovaries behave from one cycle to the next. :/ unfortunately it's really not that linear or binary bc bodies are weird.... but I'm sure we all knew that already here lol

dragonette505 · June 2017

@BusinessWife I absolutely agree.... but I think it's person to person ... so for two women with like similar stats (same age, same dx, same prognosis) you can put them both on the same protocol and one will be successful and the other not. There's really no way to even tell! I'm just trying stuff because I'd hate to wonder for ever after if something could've helped. I'm not ashamed to admit I'm at that level...lol

[Deleted User] · June 2017

@dragonette505. I 100% don't blame you!!! I hope so so hard you will be able to find your "magic bean," that does the trick. You absolutely deserve it and I am hoping all the best for you! ❤

Aera11 · June 2017

Thank you all for you input! For those that have tried it @JamieH2000 @Sugarbreak @LeFemmeViolette @BusinessWife was it mixed with your other meds or taken alone? Was it intramuscular or in the stomach? So far I've only mixed my meds (Gonal Menopur cetrotide) so it's kind of been of breeze...just wondering how this will effect my other stims.

LeFemmeViolette · June 2017

@Aera11 It was not mixed with the other meds. It was it's own separate injection from an insulin-type syringe/needle. So, yes, unfortunately it'd be an added daily injection (but just for like 5 days).

JamieH2000 · June 2017

Mine was also a seperate injection, but I don't recall it being too bad of one! I have never mixed my meds, so I guess I was just used to 3-4 shots per night. I did get pretty bruised that cycle....

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