Trouble TTC

Letrozole side effects?

Hi everyone,
I was just wondering what side effects you had on Letrozole? I'll be starting it in (probably) less than a week and want to know what I should be prepared for...
Thanks!
Me: 26, DH: 26
TTC #1 since July 2016
Dx: PCOS, on Metformin since Feb 2017
  • June 17 - Letrozole - BFN
  • July 17 - Letrozole - BFP - MMC confirmed 30/08
  • November 17 - Letrozole - BFN
  • December 17 - Letrozole - BFP!

Pregnancy Ticker



Re: Letrozole side effects?

  • kristimh80kristimh80 member
    edited May 2017
    @tops-2 Only main side effect I got from femara / letrozole was hot flashes. Some people say they get headaches, but just drink a decent amount of water and you shouldn't have any issues. 


    TTC #1 since April 2015
    June 2016 - CP
    2017 - Medicated Cycles & IUI's
    IVF w/ PGS  - January 2018
    FET #1 - April 2018 - BFN
    ERA Cycle May / June 2018
    ERA Biopsy June 2018 ~ Results: receptive (no change)
    FET #2 - July 2018 - BFP <3 Beta #1 - 137 Beta #2 - 410
    U/S #1 7wk1d - HB 144 U/S #2 9w1d HB 166
    Anatomy Scan 1st 11/2/18 2nd AS 11/19
    EDD March 28, 2019
    Baby Girl born 3/26/19  <3



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  • tops-2tops-2 member
    Thank you :) I've been told they make you tired too, so I'll probably take them at night
    Me: 26, DH: 26
    TTC #1 since July 2016
    Dx: PCOS, on Metformin since Feb 2017
    • June 17 - Letrozole - BFN
    • July 17 - Letrozole - BFP - MMC confirmed 30/08
    • November 17 - Letrozole - BFN
    • December 17 - Letrozole - BFP!

    Pregnancy Ticker



  • @tops-2 I haven't had any obvious side effects on letrozole, but I'm also on the lowest possible dose, I think. But I also had no obvious side effects on clomid so I may not be as susceptible as others. Hope you're in the no side effects camp, too!
  • @tops-2 I think it is a wise decision to take them at night.  Whenever I was on Letrozole, I was exhausted.  Even when I took them at night, I was still pretty tired during the day but I think it took the edge off a bit.
    Me:33, DH:38 Married: 8/2/2014
    TTC #1 Since: April 2015
    Unexplained Infertility

    Cycle 1&2 : Clomid 50mg- BFN
    Cycle 3: Letrozole 2.5mg- BFN
    Cycle 4: Letrozole 5mg- BFN
    Cycle 5: HSG-normal
                  Clomid 100mg+ Estrace- BFN
    Cycle 6: Letrozole 5mg+Trigger shot+IUI+Progestrone- BFN
    Cycle 7: Letrozole 5mg, Cyst found during follicle check
    Cycle 8: Birth control to treat left ovary cyst
    Cycle 9: Letrozole 7.5mg+Trigger shot+IUI+Progesterone- BFN
    Cycle 10: Letrozole 7.5mg, 2 Cysts found during follicle check
    Cycle 11: Clomid 100mg+Estradiol+Trigger shot+IUI+Progesterone- BFN
    Cycle 12: Clomid 100mg- BFN
    Cycle 13-16: Natural attempts while awaiting IVF 
    Cycle 14: IVF-BFN

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