My husband's fertility doc just called because his final chromosome test just came back. Our doc shared that they did find a Y chromosome section deletion. The good news is that it's not an A or B section deletion, which would mean a 0% chance of sperm. The C section deletion means that there's an 80% chance that he does have sperm that they could harvest. (I'm going to be Googling AZF C deletions like crazy tonight!) The doc wants to try for an IVF procedure and get the ball rolling as soon as possible, since he is optimistic that we will be able to find sperm. He's already put in a consult for the fertility institute to call us so we can start the process. He even gave us his number so we could call if we don't hear back from them by the end of the week!
The scary part is that he told us to have a discussion about what we will do if we are in the
20% that doesn't have sperm due to the chromosomal deletion or if we would want to do a gender selection with the (hopeful)
embryos, as this genetic condition would be passed on to a boy. It's so nice to finally have a diagnosis, but at the same time, the reality is jarring.
I have a million-billion thoughts and questions. All of you have given me such good advice and support, but I know we have a road ahead of us from here, especially if there's a long waiting list right now. I'm going to start taking baby aspirin, since I know my uterine lining isn't lusciously thick like when I was in my 20s. Anything else that you recommend that I should do to start prepping? (I'm going to stalk past boards, too.)
Me: 35 DH: 28
TTC since June 2016
Azoospermia diagnosis (zero count) Dec 2016
AZFc chromosome microdeletion discovery March 2017
Unsuccessful TESE for DH in August 2017
October 2017 IVF with donor sperm
29R, 24M, 16F, 2d5, 4d6 (6 embryos total)
Only 3 could have PGS. 2/3 normal. 5 embies frozen
12/15/17 FET #1 (1 embryo)--CP
2/7/17 FET #2 (2 embryos)--BFN
Chronic endometritis diagnosis May 2018
ERA Sept 2018--borderline receptive--12 more hours of progesterone
Abnormal SIS Oct 2018
Repeat hysteroscopy Nov 1. Treated recurring endometritis.
12/4/18 FET #3 (2 embryos)--BFN
Our journey has come to an end.
~*~*~Nevertheless, she persisted~*~*~
Re: Surprise doc call: the good, the bad, and the ugly
BFP #2: 4.14.16 CP: 4.17.16
BFP #3: 6.10.2016 CP: 6.17.16
RE appt: 6.27.2016- saline sono all clear
Progenity: + carrier Tay-Sachs, Gaucher's, hemachromatosis. DH: carrier Alpha 1 anti-trypsin
PCOS, hypothyroid, MTHFR, hx of LEEP in 2006
Clomid + TI Cycle #1: 50mg Trigger 8.24.2016- BFN
Clomid 75mg + IUI#1 9.25.2016- BFP #4 10/6
Beta #1 15 Beta #2 38 Beta #3- 71 beta #4 171 Beta # 5- 21 Natural MC 10/21
HSG- clear
IVF Jan 2017
Egg Retrieval 1.22.17: 32 eggs retrieved,29 mature, 24 fertilized, 14 to blastocyst for biopsy
PGS results: 4 PGS normal 2 XX, 2 XY
FET: 3.13.2017 for 2 PGS embryos
Beta#1: 3.24.2017......... 78; Beta # 2 241; Beta #3 4198
Baby BOY due 11.29.2017
TTC since June 2016
Azoospermia diagnosis (zero count) Dec 2016
AZFc chromosome microdeletion discovery March 2017
Unsuccessful TESE for DH in August 2017
October 2017 IVF with donor sperm
29R, 24M, 16F, 2d5, 4d6 (6 embryos total)
Only 3 could have PGS. 2/3 normal. 5 embies frozen
12/15/17 FET #1 (1 embryo)--CP
2/7/17 FET #2 (2 embryos)--BFN
Chronic endometritis diagnosis May 2018
ERA Sept 2018--borderline receptive--12 more hours of progesterone
Abnormal SIS Oct 2018
Repeat hysteroscopy Nov 1. Treated recurring endometritis.
12/4/18 FET #3 (2 embryos)--BFN
Our journey has come to an end.