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Progesterone suppositories???

PeaGreen421 PeaGreen421 member
in Infertility
Hi! I started progesterone suppositories (crinone 8%) almost a week ago. Currently 11dpiui. I am having a ridiculous amount of watery cm. I know clumps are a side effects from progesterone suppositories, but what about watery cm? Anyone have any insight on this?? 
TMI- but i was sitting down because my sister was doing my hair, when i got up, I went to the bathroom and it had soaked through my panties and through my yoga pants
Me (26) + DH (29)
One ovary, one tube. Annovulation. 
Low sperm count. 
Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
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Re: Progesterone suppositories???

  • LoveDontCostAThingLoveDontCostAThing member
    I have done the progesterone suppositories before (not crinone)...the really messy ones, and they ALWAYS leaked.  This time they put me on crinone 8%, but took my first dose this morning...not too much leaked, but I'll keep you posted as I progress in taking it!
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


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  • hibiscus118hibiscus118 member
    Ughhh I totally forgot about those fun times until I saw your post.  But yes, when I was on endometrin it happened to me a few times.  I thought I peed myself or was bleeding through.   I guess it's normal?!?  I never really asked. 
    TTC since:  1/2015
    11/16:  IVF #1.  BFN
    2/23/17:  FET with a BFP on 3/8/17.
    EDD: 11/11/17 with a baby GIRL!

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  • PeaGreen421 PeaGreen421 member
    @LoveDontCostAThing yes keep me posted! This is my sixth day, each day it gets worse! Lol

    @hibiscus118 that's why I went to the bathroom, I was like "period?!?" And was like ... "uh no?" Haha glad it's normal! 
    Me (26) + DH (29)
    One ovary, one tube. Annovulation. 
    Low sperm count. 
    Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
    Report Reply
  • baseballhoneybaseballhoney member
    I have done the suppositories for 6 cycles now. Normally I just wear a light pad or pantyliner like the whole time I'm doing them. It leaks and sometimes I spot from the irritation. My doc told me it was normal. 
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  • famiylgrl86famiylgrl86 member
    I get that way too. Does it make anyone else really tired? The last few days I've been beyond exhausted, sleeping more than I ever have in the past. I would love to believe it's a symptom since I'm 3dp5dt but I doubt it's that. 
    Pregnancy Ticker
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  • PeaGreen421 PeaGreen421 member
    @famiylgrl86 I haven't been too tired, but I have had really bad lower back pain that comes and goes. Not sure if this is also a side effect  
    @baseballhoney thank you for the input! Glad I'm not alone! 
    Me (26) + DH (29)
    One ovary, one tube. Annovulation. 
    Low sperm count. 
    Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
    Report Reply
  • StuuuaaartStuuuaaart member
    I have had leaking too but I'm also spotting a lot. Every day. It's brown but it's literally every day. I spoke to my nurse last week who said it was normal but it's making me so nervous. 
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  • baseballhoneybaseballhoney member
    @famiylgrl86 I get really exhausted when I am on them. I feel like I could sleep all day. It's a side effect too
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  • LoveDontCostAThingLoveDontCostAThing member
    @Stuuuaaart -I spotted brown today on the applicator..and it's only my second dose...good to know it's normal.  I also had my ER yesterday, so they said spotting could happen.

    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


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  • famiylgrl86famiylgrl86 member
    @baseballhoney haha okay good glad it't not just me! 
    Pregnancy Ticker
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  • LoveDontCostAThingLoveDontCostAThing member
    I'm not sure which are worse...the crinone or the progesterone suppositories.  The suppositories are definitely more messy, but the applicator for the crinone isn't comfortable, and I can see as the days go on it becoming more uncomfortable.  TMI...it's hard to shove it up there, so I'm hoping it's all getting in....fun times.
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • PeaGreen421 PeaGreen421 member
    @LoveDontCostAThing as far as getting it up there, my CM is so freaking watery there is no issues with that! haha but definitely fun times.
    Me (26) + DH (29)
    One ovary, one tube. Annovulation. 
    Low sperm count. 
    Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
    Report Reply
  • fivetimesnoluckfivetimesnoluck member
    @PeaGreen421 any time I have had to take them, I inserted at night so it could mostly absorb while I wasn't active. I also always wore a liner. Good luck! Are you testing early or waiting until 14 dpIUI?

    Me: 40, DH: 35 / Married: 2009; TTC #1: 2013

    2013 - 2015: 5 pregnancies —> 5 miscarriages

    TTCAL with RE (RPL specialist): February 2016

    2016: 3 medicated TI cycles —> 3 medicated IUI cycles: All BFN

    Donor Egg IVF Transfer: May 1, 2017

    May 11, 2017: BFP!! Beta #1: 449.1, Beta #2: 844, Beta #3: 1714

    EDD: 1/17/18, it's a GIRL!  <3 E. L. A. born 12/7/2017








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  • PeaGreen421 PeaGreen421 member
    @fivetimesnoluck my RE instructed me to take them in the AM :(  I started wearing liners because its so gross lol
    I am waiting until beta on 14dpiui. So nervous!! 
    Me (26) + DH (29)
    One ovary, one tube. Annovulation. 
    Low sperm count. 
    Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
    Report Reply
  • fivetimesnoluckfivetimesnoluck member
    @PeaGreen421 - ugh, that's lame! Hopefully you'll have a good beta and all that leakage will be worth it!  ;)

    Me: 40, DH: 35 / Married: 2009; TTC #1: 2013

    2013 - 2015: 5 pregnancies —> 5 miscarriages

    TTCAL with RE (RPL specialist): February 2016

    2016: 3 medicated TI cycles —> 3 medicated IUI cycles: All BFN

    Donor Egg IVF Transfer: May 1, 2017

    May 11, 2017: BFP!! Beta #1: 449.1, Beta #2: 844, Beta #3: 1714

    EDD: 1/17/18, it's a GIRL!  <3 E. L. A. born 12/7/2017








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  • PeaGreen421 PeaGreen421 member
    @fivetimesnoluck thank you! And I'd leak the rest of my life for a LO ;) haha 
    Me (26) + DH (29)
    One ovary, one tube. Annovulation. 
    Low sperm count. 
    Clomid+trigger+IUI (2million/83% motility) = 02.24.17 = ??
    Report Reply
  • LoveDontCostAThingLoveDontCostAThing member
    I have to take one dose in the morning and one at night! :(
    Me: 33, DH: 40
    July 2016: IVF #1 (froze embryos)
    Aug. 2016: Hysteroscopy to remove a few polyps & Laparoscopy
    Oct. 2016: FET #1 BFN
    Nov. 2016: FET #2 BFP (ended in CP)
    March 2017: IVF #2 Fresh Transfer of 2 Blasts = BFP!!! (EDD: 11/27/17)
    Froze 5 Blasts
    DS born on 11/2/17!!!  
    Back to try for Baby #2 :)


    Report Reply
  • katherindkatherind member
    My RE has me on Crinone 1x day in the morning. I'm on day 3 of at least 14 (could be longer if directed at my next appt on 3/30) and am experiencing a whole lot of 'yuck' down there too. I've been wearing a light pad just to keep it all contained. I get both a thick discharge and at other times it feels like water or AF. I panic and rush to the ladies room and find it's just the Crinone.

    *km*
    me 29  |  him 32  |  married: 4/27/2013

    TTC#1 (2/14/2017 - 4/7/17):
    Menopur = 19.66mm (R) & 17.02mm (L)| Ovidrel: 3/14/2017 | TIC 3/14-3/17/17 | *TWW* | Beta #1 3/30: 7.27 | Beta #2 4/3: 11.94| Beta #3 4/5: 8.02 | Beta #4 4/7: 2.24 | Ended as chemical pregnancy.

    TTC#2: (4/10/2017 - 5/12/17):
    Menopur = 13.59mm (R) & 21.68mm (L)| Ovidrel: 4/27/17 | TIC 4/27-4/30/17 | *TWW* | Beta #1: 0.1 = BFN

    TTC#3: (5/16-present)
    Menopur = 17mm + 13.5mm (L) 19.5mm (R) | CD11 Ovidrel 5/26/17 | TIC 5/26-5/28/17 | *TWW* | Beta #1 6/12: 9.91 | Beta #2 6/14: 13.89 | Beta #3 6/16: 20.81 | Beta #4 6/19: 41.46 | Beta #5 6/21: 24.50 | Beta #6 6/30: TBD - Will test until numbers reach zero.
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  • thothscribe81thothscribe81 member
    I am starting Crinone tonight and then my doc said to take it in the morning starting tomorrow, just once a day.  I'm glad I'm reading these boards as I'll be prepared with liners!!!  How are the side effects for everyone? 
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  • katherindkatherind member
    @thothscribe81 I'm on day #3 of the Crinone. I get very crampy / bloated. This subsides a little bit late at night, but then comes back after taking the next dose in the morning. Other than that, I haven't experienced many other side effects.

    *km*
    me 29  |  him 32  |  married: 4/27/2013

    TTC#1 (2/14/2017 - 4/7/17):
    Menopur = 19.66mm (R) & 17.02mm (L)| Ovidrel: 3/14/2017 | TIC 3/14-3/17/17 | *TWW* | Beta #1 3/30: 7.27 | Beta #2 4/3: 11.94| Beta #3 4/5: 8.02 | Beta #4 4/7: 2.24 | Ended as chemical pregnancy.

    TTC#2: (4/10/2017 - 5/12/17):
    Menopur = 13.59mm (R) & 21.68mm (L)| Ovidrel: 4/27/17 | TIC 4/27-4/30/17 | *TWW* | Beta #1: 0.1 = BFN

    TTC#3: (5/16-present)
    Menopur = 17mm + 13.5mm (L) 19.5mm (R) | CD11 Ovidrel 5/26/17 | TIC 5/26-5/28/17 | *TWW* | Beta #1 6/12: 9.91 | Beta #2 6/14: 13.89 | Beta #3 6/16: 20.81 | Beta #4 6/19: 41.46 | Beta #5 6/21: 24.50 | Beta #6 6/30: TBD - Will test until numbers reach zero.
    Report Reply
  • thothscribe81thothscribe81 member
    @katherind thanks for the heads up!  I'm preparing myself for the cramping everyone talks about!!  Hopefully it won't be super bad!  As long as I know its a good thing and not my period I think i'll be okay lol
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  • katherindkatherind member
    @thothscribe81The cramping hasn't been too bad for me so far. It's very noticeable and tender in my lower abdomen, but it's not excruciating by any means.

    *km*
    me 29  |  him 32  |  married: 4/27/2013

    TTC#1 (2/14/2017 - 4/7/17):
    Menopur = 19.66mm (R) & 17.02mm (L)| Ovidrel: 3/14/2017 | TIC 3/14-3/17/17 | *TWW* | Beta #1 3/30: 7.27 | Beta #2 4/3: 11.94| Beta #3 4/5: 8.02 | Beta #4 4/7: 2.24 | Ended as chemical pregnancy.

    TTC#2: (4/10/2017 - 5/12/17):
    Menopur = 13.59mm (R) & 21.68mm (L)| Ovidrel: 4/27/17 | TIC 4/27-4/30/17 | *TWW* | Beta #1: 0.1 = BFN

    TTC#3: (5/16-present)
    Menopur = 17mm + 13.5mm (L) 19.5mm (R) | CD11 Ovidrel 5/26/17 | TIC 5/26-5/28/17 | *TWW* | Beta #1 6/12: 9.91 | Beta #2 6/14: 13.89 | Beta #3 6/16: 20.81 | Beta #4 6/19: 41.46 | Beta #5 6/21: 24.50 | Beta #6 6/30: TBD - Will test until numbers reach zero.
    Report Reply
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