Debating doubling my Femara (Letrozole)

Re: Debating doubling my Femara (Letrozole)

• sugarhead-2 member

  February 2017

  I've never taken letrozole. This is for IUI right? I think the goal is 1-3 good sized follicles. So you can definitely talk to your REI about increasing the dose.  Good luck!
  
  -Sugar
  
  
  

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• baseballhoney member

  February 2017

  I was originally on the 10 mg dose for the first 3 cycles, but on the 3rd cycle I had too many follicles that were big enough so they cut my dose down to 5 mg for 3 cycles. I have only been getting 1 or 2 follicles so now they decided to up my dose back to the 10 mg. 

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• LadyMillil member

  February 2017

  Please don't double your dose without talking to your doctor first. I know someone IRL that did that and ended up in the emergency room.

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• junicek member

  February 2017

  @LadyMillil what does IRL mean? 

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• bpietronicco member

  February 2017

  @junicek IRL means in real life

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• seethosestars member

  February 2017

  The range of dosing for letrozole is actually 2.5-10 mg (2.5, 5, 7.5 and 10) so you could consider asking about stepping up to 7.5 mg.  My understanding though is that letrozole is supposed to be dosed at the lowest amount needed to give you a strong ovulation (have you had your Day 21 P checked?) and not necessarily to give you a ton more eggs released.  Definitely talk to your doctor - I'd worry about cysts etc if you just double it without recommendation!

  
  Married since 2011
  TTC since Oct 2014
  DOR + MFI
  3 failed IUIs; IVF August 2017
  

  FET January 2018 - BFP

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• ReesaAnne16 member

  February 2017

  My doctor told me going from 7.5mg to 10mg doesn't increase follicle growth (just increases side effects) so max dose in her opinion is 7.5mg
  
  In order to get me to go from 1 follicle to 2 each cycle, instead of raising the dose, my RE extended the length of time I was on it, and started it earlier (from CD3-7 to CD2-8). 
  
  PS it's a bad idea to mess around with these meds without your doctors recommendation. 

  Me 34 DH 36 Married since July 2010 
  MFI (High DNA Fragmentation) & Mild endometriosis
  

  TTC #1 since June 2015 
  Aug 2016 - May 2017  6 IUI's with letrozole - BFN
  April 2017 - laparoscopy to remove mild endo
  June 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU - Cancelled early ovulation, no eggs retrieved. 
  Aug/Sept 2017 - Mini IVF letrozole 12.5mg, Gonal-F 75IU, cetrotide - 13 eggs retrieved, 11 mature
  5 eggs ICSI'd 6 eggs frozen - 1 day 5 blast transfered, 2 expanded blast frozen - BFP!
  May 2018 - Baby girl born - Our Joy
  
  TTC #2 since July 2019
  July 2019 - FET - BFN
  Jan 2020 - FET - canceled due to family health issues
  Mar 2020 - FET - low beta - chemical pregnancy
  July 2020 - ICSI'd remaining 6 eggs - 3 fertilized - 2 survived to early blast stage, transfered both - Chemical Pregnancy
  

  
  

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• junicek member

  February 2017

  @seethosestars and @ReesaAnne16 I've ovulated on my own for the most part so my Dr just put me on 5mg of Femara to be sure. I took 7.5mg today (day 3) but you've made some good points. This may be my last iui (and we aren't going ivf) so I'm just trying to maximize my chances. 

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