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Diclegis

virginiaunicorn11virginiaunicorn11 member
in July 2017 Moms
Did you ladies see this news recently about Diclegis? 
https://www.npr.org/sections/health-shots/2017/01/06/508562318/morning-sickness-pill-gets-second-look-from-persistent-researchers

I did a Search and didn't see the article mentioned, though see lots of mamas are taking the medicine
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Re: Diclegis

  • JAM85JAM85 member
    edited January 2017
    Just read the article and it basically has no information on what the potential side effects that this one doctor seems to be calling into question and trying to use this study from the 1970s for which is frustrating. I take unisom/b6 so essentially the same and did last pregnancy and the difference for me was the difference between actually being able to eat food and throwing up all the time and barely eating 500 calories in a day. Of course zofran is no different and I believe has a lot more questions raised against it recently in terms of fetal side effects but no concrete conclusions have arisen. Of course at this point no one taking either in this group will be able to chnage anything but hopefully more research is done with credible studies and statistics. 
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  • irishrose54irishrose54 member
    I did see this article the other day. If I am remembering correctly it didn't really seem to draw any conclusive evidence. I am not taking Diclegis myself, but is the antihistamine unisom or is it something different? I read about the recall in the 70s, and heard that since they took that off the market (whatever the drug in the 70s was called, I can't recall) doctors were prescribing unisom and b6 often and it does not have a negative impact on babies. I read that in "Expecting Better" (book). 


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  • JAM85JAM85 member
    edited January 2017
    @irishrose54 so diclegis is the same as unisom/b6 and correct the one drug called into question had a third ingredient not listed but was apparently the ingredient called into question and then removed and this came out sans whatever that was. I'm sure if I dug I could find it. I agree I hate when articles seem to bring up a mixed bag of questions and anxiety for an already anxious group (pregnant women) with no actual facts or evidence 
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  • irishrose54irishrose54 member
    @JAM85  The worries never end! 


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  • notachanskinotachanski member
    thank you for sharing @virginiaunicorn11 !
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  • dancegurl1118dancegurl1118 member
    I took unisom through my entire first pregnancy before it was formulated as diclegis. I didn't take it for nausea (was working 40 hour nights at the time and was a zombie who couldn't sleep) but took it since it was a pregnancy approved sleep-aid. All of the sudden I put two and two together one day and was like "holy shit I feel so much better on the days where I took unisom the night before". 

    I read through the critique of the FDA approval as well as the studies (medical journals and research studies are crack to my nerdy ass) and will continue to take diclegis as I have been, sparingly. I personally do not see any risk, or correlated risk, just some limitations in the research that led to FDA approval, which is normal. 
    TTC: 1/2014 BFP: 9/24 EDD: 6/8/2015 Sorry for the poor man's siggy...ticker won't load regardless of how many tips I read.
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  • LoveLee85LoveLee85 member
    My doctor that I trust said the active ingredient in unisom(for my pregnancy insomnia) has been safe forever. He said many decades ago there were 3 products out, 2 of the 3 they found out had terrible side effects and all 3 were pulled from backlash and fear. I guess it scared people away from the active ingredient in unisom. But he said the same active ingredient in unisom is in Tylenol PM, which is also safe. It just doesn't have the Tylenol. Anywho, inforgot a lot of the exact details but he explained it all to me and I trust him with my life and my unborn babies. Obviously, just because I'm comfortable with it doesn't mean you will be. I would suggest talking to your doctor before anyone panics! 
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  • LoveLee85LoveLee85 member
    Also, maybe a dumb question but how are some people taking diclegis 3 or 4 times a day for morning stickiness....if Unisom/B6 is considered the same thing??? Do you sleep all day long? Lol I take the unisom for pregnancy insomnia but I don't do the B6 part. And that being said, the unisom doesn't help with my morning sickness. I have been takin it nightly, one pill 25mg, since 9th week to sleep through the night better. Like I said, probably dumb question but thanks in advance. 
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  • dancegurl1118dancegurl1118 member
    I have no idea. I normally take one at bedtime. If I take two I'm groggy and exhausted all day and want to go to sleep at 7pm. Even when I used to just take unisom I would take half a pill. Must effect people differently!
    TTC: 1/2014 BFP: 9/24 EDD: 6/8/2015 Sorry for the poor man's siggy...ticker won't load regardless of how many tips I read.
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  • greenbean-2greenbean-2 member
    I've been taking unisom/b6 around the clock. I take a full unisom at night and like a quarter pill a couple times a day (it's hard to break it up exactly into quarters). Do I feel sleepy? Yes. Is it better than the alternative? Yes. The grogginess was the worst for the first couple days and then I think I just got used to it. 
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  • LoveLee85LoveLee85 member
    GreenBean said:
    I've been taking unisom/b6 around the clock. I take a full unisom at night and like a quarter pill a couple times a day (it's hard to break it up exactly into quarters). Do I feel sleepy? Yes. Is it better than the alternative? Yes. The grogginess was the worst for the first couple days and then I think I just got used to it. 
    It must just do different things for different people! Unisom doesn't make me 'sleepy' or 'groggy', within ten minutes I'm literally dead where I sit and passed out for hours!!!!! Lol I could not imagine taking this all day! 
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  • AnnaKaieAnnaKaie member
    I took unisom almost every night at the end of my last pregnancy. It was a life saver. It didn't make me go to sleep, but it made it where I could go to sleep. 

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  • greenbean-2greenbean-2 member
    LoveLee85 said:
    GreenBean said:
    I've been taking unisom/b6 around the clock. I take a full unisom at night and like a quarter pill a couple times a day (it's hard to break it up exactly into quarters). Do I feel sleepy? Yes. Is it better than the alternative? Yes. The grogginess was the worst for the first couple days and then I think I just got used to it. 
    It must just do different things for different people! Unisom doesn't make me 'sleepy' or 'groggy', within ten minutes I'm literally dead where I sit and passed out for hours!!!!! Lol I could not imagine taking this all day! 
    That's really interesting! This makes me feel the same as when I take a Benadryl or Dramamine - I could take a nap, but if I have stuff to do I can push past it. I also think taking the tiny doses helps. I'm sure I would be a zombie with a full tablet during the day. 
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  • LoveLee85LoveLee85 member
    edited January 2017
    GreenBean said:
    LoveLee85 said:
    GreenBean said:
    I've been taking unisom/b6 around the clock. I take a full unisom at night and like a quarter pill a couple times a day (it's hard to break it up exactly into quarters). Do I feel sleepy? Yes. Is it better than the alternative? Yes. The grogginess was the worst for the first couple days and then I think I just got used to it. 
    It must just do different things for different people! Unisom doesn't make me 'sleepy' or 'groggy', within ten minutes I'm literally dead where I sit and passed out for hours!!!!! Lol I could not imagine taking this all day! 
    That's really interesting! This makes me feel the same as when I take a Benadryl or Dramamine - I could take a nap, but if I have stuff to do I can push past it. I also think taking the tiny doses helps. I'm sure I would be a zombie with a full tablet during the day. 
    Benadryl also has strong powers over me. Haha I know some people that Benadryl makes them wired and hyper! 

    ETA: one time I had surgery and pain meds make me insanity pukey, so doctor gave me zofran. Well it solved the puke problem but it was also lights out for no less than 10 hours after one small dose of zofran!!!!! I must just be weird BUT Zofran has a side effect of sleepyness(a huge understatement in my case). 
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  • Pricelessmommy3Pricelessmommy3 member
    Diclegis I was told is time released. So perhaps that's how it might not make you as drowsy?. I've been taking unisom and b6 and it has been a total life changer! My other pregnancies I was throwing up daily, having to go in for fluids at least twice in the first trimester. This is the first pregnancy I've gained weight in the first trimester. It makes me sleepy, so I just take it at night bc I still have 2 at home with me. My dr told me zofran is no longer recommended until the second trimester now. Zofran never worked well for me anyway. 
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