Infertility

Folate vs folic acid and mthfr

for those of you who have the mthfr Gene mutation, have you switch to a vitamin that has folate in it instead of the folic acid? Any suggestions on a brand that you like? 
Thanks!

Re: Folate vs folic acid and mthfr

  • I was put on metanex. First re said 1 per day; second re said 2 per day. So, that's what I've been on. 
    Me:32 DH:36
    Me: DOR, poor egg quality, MTHFR
    DH: MFI
    TTC since 3/2014
    2015: 3 IUI's-BFN
    12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
    3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 
    3/2016: RE suggested donor eggs- taking an ivf break and to supplement 
    9/2016: 3rd ivf cycle-cancelled due to early ovulation
    Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
    1/9/17: transferred 1 embryo-BFP 1/16
    1/18/17: beta #1-104
    1/20/17: beta #2-174
    2/2/17: first u/s, heartbeat of 107 at 6w1d
    7/20/17: baby boy born at 30+3 via emergency c-section 


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  • I take Smarty Pants prenatal gummies. They have folate instead of folic acid and are actually pretty yummy! 
  • @20t how many do you take? It says up to 6 per day?  
  • @Kp214 interesting about RE saying 2 a day. I'm only on 1 but wondering now if its enough... eek. 

    I'm also on Metanx (well, Foltanx which is the generic brand of metanx). You need a prescription but it's not covered by insurance since it's categorized as a "food" product. 

    Very important if you have MTHFR to not have folic acid. Good luck!
    ---
    Started TTC April 2011
    Me: 32, DH: 32
    Diagnosis: Endometriosis

    • 2012 - 3 Rounds clomid - all BFN
    • 2013 - 1 Fresh IVF with 2 day 3 embryos - BFN
    • 2014 - 1 Frozen IVF with 2 day 5 embryos - BFN
    • Took a long break, continuing trying naturally
    • Feb 2016 - Biopsy = Endo, DH sperm improved from 1% to 6% morphology
    • March 2016 - Fresh IVF cycle with acupuncture & intralipids: 20 eggs retrieved (17 mature), 7 ICSI'd fertilized, 9 naturally fertilized. 16 total embryos!
    • April 8th - 2 embryos (1ICSI and 1 Natural) transferred. (7 blastocysts frozen), April 18th - Beta = BFN
    • Sept 23rd - Lupron Depot Injection for Endo control
    • Nov 15th 2016 - Started daily Lupron Injections for upcoming FET
    • Nov 22 - Baseline US/BW - Intralipid Infusion - Start Meds for FET with immune protocol
    • Dec 16th FET transfer of 3 embryos (1 - AA, 2 - BB)
    • TW below
    • Dec 22nd - first ever bfp (very faint lines FRER & cheapie)
    • Dec 27th Beta = 192, Dec 29th Beta = 379
    • EDD - Sept 5th 2017

    - - -
    I'm a YouTube vlogger who talks about Infertility, IVF and Endometriosis. Check it out here!
    Follow along at http://liv4today.blog
    Instagram @liv4todayvlog 


  • kangasteinkangastein member
    edited December 2016
    A lot of brands now have folate in them, baby & me, new chapter, vitamin code. Pure encapsulations makes a non prenatal that is supposed to be excellent for MTHFR. My friend without MTHFR swears by the vitamin code prenatals
  • @oxinfree I spoke with a nurse that worked for brand direct pharmacy. She said that some people need 2 instead of one. She said to try 2 for a week since my new re wanted that and then see how I felt. I don't know if I feel any different, but I figure it can't hurt to be taking 2. 
    Me:32 DH:36
    Me: DOR, poor egg quality, MTHFR
    DH: MFI
    TTC since 3/2014
    2015: 3 IUI's-BFN
    12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
    3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 
    3/2016: RE suggested donor eggs- taking an ivf break and to supplement 
    9/2016: 3rd ivf cycle-cancelled due to early ovulation
    Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
    1/9/17: transferred 1 embryo-BFP 1/16
    1/18/17: beta #1-104
    1/20/17: beta #2-174
    2/2/17: first u/s, heartbeat of 107 at 6w1d
    7/20/17: baby boy born at 30+3 via emergency c-section 


  • @jodes727 yes I take 6. 3 with lunch and 3 with dinner. 
  • Just bought my Smarty Pants vitamins! My RE said to not be concerned about my mthfr because I don't have the worst kind, but I don't want to risk it! 
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