Infertility

Embryo Glue??

So, I'm getting ready to meet with my Dr next week to talk about my cycle and how we can make changes for the next one and I have really been thinking about trying to see if we could do embryo glue. Has anyone used it and found success? Both transfers ended in BFN so I'm thinking we are having implantation failure and would love thoughts.
Me: 29 DH:38
First RE Consult 3/9/2016
IVF ER 5/5/2016
23 eggs retrieved; 15 mature; 8 developed to embryos; 6 frozen day 5; 2 frozen day 6
Transfer canceled OHSS
FET #1 6/2/2016 transferred 2 embryos
Beta #1 6/15/2016 BFN
FET #2 8/1/2016 transferred last 2 embryos (lost 4 in the thaw)
Beta #1 8/12/16 BFN
IVF #2: Started stims 12/2 
ER #2 12/14/2016; 16 follies retrieved, 8 fertilized to day 1, 4 frozen day 5, and 1 frozen day 6
Praying my frosties are strong through the next thaw FX
FET # 3 2/07/2017 2 embabies thawed 2 embabies transferred
2/14/2017 *TW* First ever BFP
Beta #1 2/20/2017 277 Beta #2 2/23/2017 8,945...did I hear you right!
3/10/2017 One beating heart HR 168!! So very happy
3/10/2017 Official graduate from Jones Institute for Reproductive Health!! Couldn't help but cry
6/8/2017 Anatomy Scan proves ITS A GIRL! 
10/30/17 An angel was Born; Riley Charlize 7:50 AM my heart is so full
*Praying that 3 is our charm*


Re: Embryo Glue??

  • Yes i used it this transfer ( my ivf#2) and it worked!
    Me  Hydrosalpinx(36) & DH 0% morphology (37)
    Jan 2007- started TTC ( temp everyday and opk and clomid used 12 cycles)
    Oct 2010- Natural BFP after 22 months TTC ( NO MEDS USED)
    Feb 2011- Still birth @ 16 weeks 
    May 2011- Myomectomy to remove grapefruit size fibroid
    Jan 2015- Essure to block hydrosalpinx
    April 2015 - 1st IUI  - BFN
    May 2015 - 2nd IUI - BFN
    Aug 2015 - IVF ER: BCP, lupron, Menopur, Bravelle, HCG (Trigger Shot) 12 eggs retrieved, 8  mature, 7 fertilized, 3 to blast, 2 passed pgs ( BOYS)
    Sept 2015 - FET transferred 2 embryos passed PGS (BOYS)- BFN ( NO FROSTIES left )
    Dec 2015- ICH Brain hemorrhage
    April 2016- Start Birth Control Got cleared for IVF/ diagnosed with MTHFR gene mutation/ HUBBY HAS ABOVE NORMAL MORPH/COUNT/MOTILITY
    May 2016- Start meds for ER 
    May 1- Start Lupron for long lupron protocol
    May 13- Started Stims 300 follistim,75 menopur, 10 lupron stimmed for  10 days
    May 24-  16 eggs retrieved,  12 mature eggs, 8 fertilized, 5 to blast. qty 2 day 6 AA blast. qty 3 7 day blast grades AA and AB.
    Have 3 NORMAL PGS TESTED GIRLS. 1 "INCONCLUSIVE" embryo still good for use.
    7/8- Started AF and Estraidol patches
    8/2- FET scheduled ( HUBBY BDAY!!!) and my clinic automatically uses EMBRYO GLUE!
    8/2- Transferred 1 6AA pgs tested girl
    8/15 - Beta #1 137 I AM PREGNANT!!!! EDD 4/20/17
    8/17- Beta #2 269 
    9/1- MISCARRIAGE. Baby stopped growing at 5 weeks 3 days. 
    10/19- Have Baseline for IVF#3. Fresh transfer.
    10/21- Start stims 300 Follistim 150 Menopur and Ganirelix 
    11/2/16-ER 43 eggs retrieved. 15 mature. 9 Fertilized. All 9 still growing but 4 are leading and are 8 cell day 3 grade AA.
    11/7/16- Fresh transfer of 1 embryo
  • I used it with one of my cycles (not sure which one- they blur) and it didn't work for me. BUT I have heard great results from it! 
    What they told me, it won't force a bad pregnancy to stick, but will help a good one succeed! 
    Me 30 || DH 36
    Unexplained Infertility- Postive for MTHFR Gene Mutation

    Natural cycles with 1 miscarriage
    -3 IUI's w/ Clomid= BFN 
    -IVF #1-Follistim and Menopur= BFN
    ***11 Eggs, 10 mature, 8 fertilized, transferred 1 (day 5) 2 made it to freeze
    -FET #1- Transferred 2, day 5 embryos =BFN
    -IVF #2- Follistim and Menopur = BFN
    ***11 retrieved, 8 mature, 6 fertilized, transferred 2 (day 3), 4 made it to freeze (Follistim and Menopur) = BFN
    -FET #2- Transferred 2, day 3 embryos = BFN
    **Changed doctor**
    -IUI #4- natural cycle = BFN
    -IUI #5- Follistim (5 eggs) BFP- lead to Miscarriage  :'(
    -Laproscopic Surgery for Endometriosis, Polyp removal and Cyst removal. 
    -IVF #3- Menopur, Follistim, Lupron, Ganirellex- BFP lead to Eptopic Pregnancy  :'(
    ***11 Eggs retrieved, 10 Mature, 8 fertilized, transferred 3 embryos (day 3), 0 made it to freeze
    -Lapropscopic surgery- Removal of Fallopian Tube
    -IVF #4- Estrogen Priming with Vivelle dot, Menopur, Follistim, Ganirellex- BFP  :)
    ***15 Eggs retreived, 11 mature, 11 fertilized, 2 embryos transferred (day 3), 2 made it to freeze
    Found out I was positive for MTHFR Gene Mutation during TWW of IVF #4

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  • what is it? i have never heard of embryo glue.  very intrigued
    Lilypie Maternity tickers

    Lilypie Second Birthday tickers
  • Never heard of it...tell me more
    TTC #1 since August 2013
    Unexplained/ Endo
    Medicated IUIs # 1-3 BFN
    IVF #1- BFN
    FET #1- BFP; Ectopic pregnancy found at 7wks
    FET #2- February 2017 BFP  Beta #1- 119 (8dp5dt) Beta #2- 475 (12dp5dt)
  • Ditto... I have heard of this, but what is it exactly?

    Me: 35 DH: 41, Married since 2009

    TTC since June 2012

    Aug. 2012: CP

    2013 Several cycles of TI with Clomid = BFN

    Feb. 2014: IUI = BFN

    June 2014: IUI w/Clomid = BFN

    Jul. 2014: IUI w/Letrozole = BFN

    Apr. 2016: Consult to begin IVF

    May 2016 TI w/Follistim and Ovidrel = BFN

    Jul. 2016: BCPs, baby aspirin, Vitamin D, COQ10, DHEA, Gonal F, Menopur, Cetrotide, Novarel, Leuprolide Acetate: 21 eggs retrieved, (10 w/ ICSI, 11 w/conv. IVF) 13 fertilized

    Jul. 2016: Endometrin, Fresh Transfer 2AB = CP

    7 frozen

    Oct. 2016: BCPs, baby aspirin, Estradiol, PIO, FET 4AA = CP

    6 frozen

    Nov. 2016: Hospitalized for small bowel obstruction

    Mar. 2017: Diagnostic Laparoscopy = Twist found in intestine - part of small intestine, part of colon, and appendix removed, bowel resection - caused by Endometriosis

    May 2017: 3.75 Lupron Depot

    June 2017: FET postponed due to complex cysts in breasts

    June 2017: Endometrial scratch

    Jul. 2017: Baby aspirin, Estradiol, PIO, FET 4AA (lost 1 4AA in thaw) = CP

    4 frozen

    Sept. 2017: ERA testing

    Oct. 2017: Breast cysts biopsied

    Dec. 2017: FET

  • It's an amino acid that they put the embryo in before placing it into the uterus. It's supposed to help the embryo adhere to the lining better. 
    Me 30 || DH 36
    Unexplained Infertility- Postive for MTHFR Gene Mutation

    Natural cycles with 1 miscarriage
    -3 IUI's w/ Clomid= BFN 
    -IVF #1-Follistim and Menopur= BFN
    ***11 Eggs, 10 mature, 8 fertilized, transferred 1 (day 5) 2 made it to freeze
    -FET #1- Transferred 2, day 5 embryos =BFN
    -IVF #2- Follistim and Menopur = BFN
    ***11 retrieved, 8 mature, 6 fertilized, transferred 2 (day 3), 4 made it to freeze (Follistim and Menopur) = BFN
    -FET #2- Transferred 2, day 3 embryos = BFN
    **Changed doctor**
    -IUI #4- natural cycle = BFN
    -IUI #5- Follistim (5 eggs) BFP- lead to Miscarriage  :'(
    -Laproscopic Surgery for Endometriosis, Polyp removal and Cyst removal. 
    -IVF #3- Menopur, Follistim, Lupron, Ganirellex- BFP lead to Eptopic Pregnancy  :'(
    ***11 Eggs retrieved, 10 Mature, 8 fertilized, transferred 3 embryos (day 3), 0 made it to freeze
    -Lapropscopic surgery- Removal of Fallopian Tube
    -IVF #4- Estrogen Priming with Vivelle dot, Menopur, Follistim, Ganirellex- BFP  :)
    ***15 Eggs retreived, 11 mature, 11 fertilized, 2 embryos transferred (day 3), 2 made it to freeze
    Found out I was positive for MTHFR Gene Mutation during TWW of IVF #4

  • Atleast that was what I was told by my old doctor. And I kinda hate my old doctor soooo I could be wrong lol :lol:
    Me 30 || DH 36
    Unexplained Infertility- Postive for MTHFR Gene Mutation

    Natural cycles with 1 miscarriage
    -3 IUI's w/ Clomid= BFN 
    -IVF #1-Follistim and Menopur= BFN
    ***11 Eggs, 10 mature, 8 fertilized, transferred 1 (day 5) 2 made it to freeze
    -FET #1- Transferred 2, day 5 embryos =BFN
    -IVF #2- Follistim and Menopur = BFN
    ***11 retrieved, 8 mature, 6 fertilized, transferred 2 (day 3), 4 made it to freeze (Follistim and Menopur) = BFN
    -FET #2- Transferred 2, day 3 embryos = BFN
    **Changed doctor**
    -IUI #4- natural cycle = BFN
    -IUI #5- Follistim (5 eggs) BFP- lead to Miscarriage  :'(
    -Laproscopic Surgery for Endometriosis, Polyp removal and Cyst removal. 
    -IVF #3- Menopur, Follistim, Lupron, Ganirellex- BFP lead to Eptopic Pregnancy  :'(
    ***11 Eggs retrieved, 10 Mature, 8 fertilized, transferred 3 embryos (day 3), 0 made it to freeze
    -Lapropscopic surgery- Removal of Fallopian Tube
    -IVF #4- Estrogen Priming with Vivelle dot, Menopur, Follistim, Ganirellex- BFP  :)
    ***15 Eggs retreived, 11 mature, 11 fertilized, 2 embryos transferred (day 3), 2 made it to freeze
    Found out I was positive for MTHFR Gene Mutation during TWW of IVF #4

  • I am glad to see that it has worked for some! I am just really ready to try just about anything at this point!! This is one article that I read on it. I am still not 100% sure of the exact process but if my clinic will allow I think I definately want to try this on this try.
    https://www.yourivfjourney.com/embryo-glue-does-it-work-or-not/
    Me: 29 DH:38
    First RE Consult 3/9/2016
    IVF ER 5/5/2016
    23 eggs retrieved; 15 mature; 8 developed to embryos; 6 frozen day 5; 2 frozen day 6
    Transfer canceled OHSS
    FET #1 6/2/2016 transferred 2 embryos
    Beta #1 6/15/2016 BFN
    FET #2 8/1/2016 transferred last 2 embryos (lost 4 in the thaw)
    Beta #1 8/12/16 BFN
    IVF #2: Started stims 12/2 
    ER #2 12/14/2016; 16 follies retrieved, 8 fertilized to day 1, 4 frozen day 5, and 1 frozen day 6
    Praying my frosties are strong through the next thaw FX
    FET # 3 2/07/2017 2 embabies thawed 2 embabies transferred
    2/14/2017 *TW* First ever BFP
    Beta #1 2/20/2017 277 Beta #2 2/23/2017 8,945...did I hear you right!
    3/10/2017 One beating heart HR 168!! So very happy
    3/10/2017 Official graduate from Jones Institute for Reproductive Health!! Couldn't help but cry
    6/8/2017 Anatomy Scan proves ITS A GIRL! 
    10/30/17 An angel was Born; Riley Charlize 7:50 AM my heart is so full
    *Praying that 3 is our charm*


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