Hi Everyone, I just finished up my First IVF Cycle and ended in a BFN. We started with 16 eggs, 13 mature, 9 fertilized. On Day 3, we had a few good 7-8 cell, a few 4-6 cell, around 9 total growing in the right direction. By Day 5, I had one 3.5AA and one Morula (a little behind Blast stage) to transfer. Ended up with None to Freeze.
My doctor has ordered genetic testing for me and DH and Autoimmune Panel, as well. I do not have PCOS or Endo and no MFI. Can anyone who has been through this offer any advice???
TTC Since July 2014. August 2015: Clomid, BFN September 2015: Clomid, BFN -October Switched to RE- November 2015: Clomid 100 MG, IUI , 2 eggs= BFN February 2016: Clomid 100 MG, Gonal F, 450, 3 eggs =BFN -Took a Break for a Cyst- March 2016- Clomid 50 MG, Gonal F, 2 eggs = BFN April- May took a much needed break! June 2016- 1st IVF Cycle= 2 Transferred, None to Freeze= BFN Sept. 2016- 2nd IVF w/planned FET November 16' (NEW Clinic)~ MTHFR C6777 HET positive
I am in the same boat. This is my first IVF FET transfer. I had 4 failed IUI in the past. We had 22 retrieved but are now down to 2 low grade blasts both are 2C grade. We are having them PGS tested to see if either of them are viable.
I'm in my 2ww from my first IVF. Started with 18, 12 mature, 8 fertilized, transferred one good day 5 blastocyst and nothing to freeze. I've already had the genetics testing and all good, my amh was good and I'm under 30. If this cycle results in a bfn I'm planning on having a sit down with my re to see why on earth we went from 18 to 1.
No insight or advice here. In our cycle we had 11 retrieved, 5 fertilized and all but 2 stopped growing on day 3. So my issue was more on the fertilization rate than down the road. All my RE had to say about it was that we just needed to try again with a different egg. I wasn't as optimistic about his approach so we decided to take at least 3 cycles off to do supplements and acupuncture so if we go back to do another IVF cycle in the fall we can hopefully have a higher fertilization rate.
Me: 33, Hubby: 36 TTC since May 2014 First RE Appt - September 2015 DX: Hypothyroid, DOR IUI w/ Clomid - October 2015 - BFN ER - 2/10/16, 2 Day 3 Embryos FET - 4/15/16 - BFN Summer 2016 - Taking a break to try herbal treatment and acupuncture
@annebenton22 I suppose it's possible that your medication was too much and affected your eggs. You may also wasn't to try some supplements to improve egg quality. Acupuncture can also help. I'm sorry this happened and hope next time goes better.
Me:32 DH:36 Me: DOR, poor egg quality, MTHFR DH: MFI TTC since 3/2014 2015: 3 IUI's-BFN 12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy 3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested) 3/2016: RE suggested donor eggs- taking an ivf break and to supplement 9/2016: 3rd ivf cycle-cancelled due to early ovulation Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
1/9/17: transferred 1 embryo-BFP 1/16 1/18/17: beta #1-104 1/20/17: beta #2-174 2/2/17: first u/s, heartbeat of 107 at 6w1d 7/20/17: baby boy born at 30+3 via emergency c-section
@annebenton22- have you read the book "It Starts with the Egg"? I found it an easy read and they go through what works (and doesn't) to try to improve egg quality based on scientific research. As others have mentioned already, I also think acupuncture can help too. I am also trying a low carb/low sugar diet (which is discussed in the book too), that my acupuncturist believes helps with egg quality and quantity. Not sure I believe it 100%, but it can't hurt to eat healthy (especially with the 10 extra lbs that all the treatment and reduced exercise has given me . Good luck and hope this next round is much better!
History in Spoiler
Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015 Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive) March-May 2016: 1 TI and 2 IUIs- BFN June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary. August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid Nov 2017- Hysterscopy to remove polyp Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone Apr 2018- DE FET cancelled for lining issues Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin Baby Born born early @ 33.5 weeks due to Pre-e Back for # 2!
Re: Poor Embryo Development
1st IVF 22 retrieved 14 fertilized 0 blast
2nd IVF 16 retrieved 11 fertilized 5 blast
TTC since May 2014
First RE Appt - September 2015
DX: Hypothyroid, DOR
IUI w/ Clomid - October 2015 - BFN
ER - 2/10/16, 2 Day 3 Embryos
FET - 4/15/16 - BFN
Summer 2016 - Taking a break to try herbal treatment and acupuncture
Me: DOR, poor egg quality, MTHFR
DH: MFI
TTC since 3/2014
2015: 3 IUI's-BFN
12/2015: 1st IVF cycle-(9 follicles retrieved, 5 mature, 3 fertilized w/ICSI, transferred 1 excellent and 1 good embryo on day 3)-chemical pregnancy
3/2016: 2nd IVF cycle- canceled (3 follicles retrieved, 3 mature, all fertilized w/ICSI, 1 fragmented, 2 arrested)
3/2016: RE suggested donor eggs- taking an ivf break and to supplement
9/2016: 3rd ivf cycle-cancelled due to early ovulation
Oct./Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. 3 CCS normal embryos
1/18/17: beta #1-104
1/20/17: beta #2-174
2/2/17: first u/s, heartbeat of 107 at 6w1d
7/20/17: baby boy born at 30+3 via emergency c-section
Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
March-May 2016: 1 TI and 2 IUIs- BFN
June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze ), BFN
May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline
Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid
Nov 2017- Hysterscopy to remove polyp
Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
Apr 2018- DE FET cancelled for lining issues
Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
Baby Born born early @ 33.5 weeks due to Pre-e
Back for # 2!