Infertility

Lupron for FET - Timing and dealing with Side-effects

Hi,

This is the first time that I will be taking Lupron for an FET (0.1CC daily for about 20 days & then 0.05CC for 10) . The nurse said it doesn't matter as to when I take the shot as long as its the same time everyday.
I have heard about all the wonderful side effects of Lupron & I was wondering if anyone had pointers on what time of the day was better in order to function relatively ok at work ? Also, any other pointers for those on Lupron is also very appreaciated.

TIA!!

DH :  36, has Chronic Kidney Disease, on dialysis & is waiting on the transplant list (average wait for B+ is 5 years)

Me:   36, Hypothyroidism, PCOS, BMI 32, need to be done with "child bearing" ASAP so that I can be a Kidney donor (was fun realizing we didn't as much time as we thought :-/ )

We're TTC#1

IUI #1 : 5mcg Letrozole (CD 3-7) + Ovidrel Trigger + Had the one follicle = BFN  (March 2014)

IUI #2 : 5mcg Letrozole (CD 3-7) + 150 iu Bravelle on CD9 (after much begging!) + Had the one follicle = BFN (April 2014)

7th May 2014 - changed REs, this one seems to care (we think....)

IUI #3 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 3 follicles (2 under 15mm) = BFN(May 2014)

IUI #4 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 1 follicle + DH gave best sample so far = BFN(June 2014)

IVF#1 -  ER Only Cycle Sept-Oct 2014, 17  eggs Retrieved, 14 mature, 10 fertilized, 6 made it to Blast & post PGS  5 were not viable due to chromosomal abnormalities
Not sure where we go from here...

We're parents to two very adorable, bratty, affectionate & goofy Bernese Mountain Dog pups who would very much like a 2 legged baby brother or sister of their own!

Re: Lupron for FET - Timing and dealing with Side-effects

  • I started Lupron last week Friday and UGH the headaches! No amount of Tylenol is helping I also get the sweats at night but other than that its been okay. 

    To get through it all I just tell myself itll all be worth it in the end and that if I dont deal with it the chances of a family are slim...I also try to look up positive quotes that helps! So does being swamped at work, I have very little time to think

    BUT I am also on 10cc, hoping to have that reduced today once my RE calls.  
    Me: 34 DH: 43
    Married March 2012
    TTC #1 since 2012
    Dx: unexplained infertility (+ treated for hypothyroidism)
    May 7, 2016: IUI#1 w/Clomid - BFN :'(
    June 6, 2016: IUI #2 w/Clomid - BFN :'(
    IVF Consult 1 & 2: June 10, 2016 / July 15, 2016 
    Started Stims: July 15, 2016 (Lupron, Gonal-F, and Menopur)
    Trigger ----> 08/03 ----> ER on 08/05 ----> Transfer ------> 08/10
    BETA 1 (8/22) - 401  - BETA 2 (8/24) - 541 - BETA 3 (8/26) - 913
    Baby Chadwell's First U/S: 09/06/2016 / EDD: 04/28/2017
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  • Ohhhhhhh and I take mine between 6-9pm as instructed by my RE, I try to do it around the same time everyday though
    Me: 34 DH: 43
    Married March 2012
    TTC #1 since 2012
    Dx: unexplained infertility (+ treated for hypothyroidism)
    May 7, 2016: IUI#1 w/Clomid - BFN :'(
    June 6, 2016: IUI #2 w/Clomid - BFN :'(
    IVF Consult 1 & 2: June 10, 2016 / July 15, 2016 
    Started Stims: July 15, 2016 (Lupron, Gonal-F, and Menopur)
    Trigger ----> 08/03 ----> ER on 08/05 ----> Transfer ------> 08/10
    BETA 1 (8/22) - 401  - BETA 2 (8/24) - 541 - BETA 3 (8/26) - 913
    Baby Chadwell's First U/S: 09/06/2016 / EDD: 04/28/2017
  • I take all my meds between 6 and 8 pm. It doesn't always help with the side effect, but there isn't much to be done about them. I'm also not quite sure how you can be taking 0.1 cc. That would be like enough to fill the eye of a needle, right? I start with 20 units of Lupron, then move down to 10 units for most of the injection cycle.
    About us:
    Me - 28, Lean PCOS
    DH - 31
    Married June 2010, TTC since March 2014
    Blog: ourbinarystar.com

    FET cycle #3 Transfer July 28th 2016, Triplets born healthy on February 26th 2017 at 33w1d!

  • ddvj79ddvj79 member
    @ADRIANAC1982  Thank you so much! I think I will also take the shot 6-9pm & thanks for reminding me that in the end, it will be worth it :) 

    Oh, the headache's worry me :( I already have a chronic migraine issue (can't take any of the prophylactics when TTC), I wonder how I am going to cope...

    DH :  36, has Chronic Kidney Disease, on dialysis & is waiting on the transplant list (average wait for B+ is 5 years)

    Me:   36, Hypothyroidism, PCOS, BMI 32, need to be done with "child bearing" ASAP so that I can be a Kidney donor (was fun realizing we didn't as much time as we thought :-/ )

    We're TTC#1

    IUI #1 : 5mcg Letrozole (CD 3-7) + Ovidrel Trigger + Had the one follicle = BFN  (March 2014)

    IUI #2 : 5mcg Letrozole (CD 3-7) + 150 iu Bravelle on CD9 (after much begging!) + Had the one follicle = BFN (April 2014)

    7th May 2014 - changed REs, this one seems to care (we think....)

    IUI #3 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 3 follicles (2 under 15mm) = BFN(May 2014)

    IUI #4 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 1 follicle + DH gave best sample so far = BFN(June 2014)

    IVF#1 -  ER Only Cycle Sept-Oct 2014, 17  eggs Retrieved, 14 mature, 10 fertilized, 6 made it to Blast & post PGS  5 were not viable due to chromosomal abnormalities
    Not sure where we go from here...

    We're parents to two very adorable, bratty, affectionate & goofy Bernese Mountain Dog pups who would very much like a 2 legged baby brother or sister of their own!

  • ddvj79ddvj79 member
    Thanks @AandDM2014! I am guessing they mean 1CC which would be 10units...I should probably double check.
    How are your side-effects with the Lupron ? I've never been on this before...hopefully I will last a month :)


    DH :  36, has Chronic Kidney Disease, on dialysis & is waiting on the transplant list (average wait for B+ is 5 years)

    Me:   36, Hypothyroidism, PCOS, BMI 32, need to be done with "child bearing" ASAP so that I can be a Kidney donor (was fun realizing we didn't as much time as we thought :-/ )

    We're TTC#1

    IUI #1 : 5mcg Letrozole (CD 3-7) + Ovidrel Trigger + Had the one follicle = BFN  (March 2014)

    IUI #2 : 5mcg Letrozole (CD 3-7) + 150 iu Bravelle on CD9 (after much begging!) + Had the one follicle = BFN (April 2014)

    7th May 2014 - changed REs, this one seems to care (we think....)

    IUI #3 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 3 follicles (2 under 15mm) = BFN(May 2014)

    IUI #4 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 1 follicle + DH gave best sample so far = BFN(June 2014)

    IVF#1 -  ER Only Cycle Sept-Oct 2014, 17  eggs Retrieved, 14 mature, 10 fertilized, 6 made it to Blast & post PGS  5 were not viable due to chromosomal abnormalities
    Not sure where we go from here...

    We're parents to two very adorable, bratty, affectionate & goofy Bernese Mountain Dog pups who would very much like a 2 legged baby brother or sister of their own!

  • I take mine between 7-9 pm.  Sometimes I'm at work during this time but I sneak away to the bathroom and do my shot.  If I get headaches I use tylenol and sometimes I put a small cotton ball with 2-3 drops of peppermint essential oil on my name badge (when I'm at work) or near my head (when I'm at home).  It does seem to help.  We do aromatherapy at work for patients whose pain meds aren't quite cutting it which is why I tried the peppermint oil in the first place. 

    me:41 dh:42
    me:PCOS, blocked left fallopian tube, hyperprolactinemia  (dh's swimmers are perfect/normal)
    Tried 3 rounds of clomid with Ovidrel trigger (BFNs)
    May/June 2016 IVF   6/1 ER 7 eggs retrieved, 7 fertilized via ICSI  6 embryos made it to blasts.
    6/6 2 AA embryos transfered, 4 BBs frozen
    Beta 6/18  -- BFN
    FET #1 August 22 BFN
    Dec 2016/Jan 2017 Round 2 was a bust. 6 eggs, Only 1 embryo made it, no transfer
    FET #2 cancelled 10/17 due to uterine polyps. Postponed until 9/2018 due to hip replacement.

    FET #3 9/11/18 Uterine scratch and antihistamine protocol/lovenox done this time. 2 AA hatching blasts put in.  BFP 9/20/18!! 

  • @ddvj79 Small world, I suffer from Chronic Migraines too. I am convinced that all the meds I was taking caused my IF problems! 

    I had migraine surgery in October of 2015 and that helped get me off all the meds and all my numbers have drastically changed for the better. My RE is even amazed.  So having headaches with the Lupron is very difficult but hopefully only temporary
    Me: 34 DH: 43
    Married March 2012
    TTC #1 since 2012
    Dx: unexplained infertility (+ treated for hypothyroidism)
    May 7, 2016: IUI#1 w/Clomid - BFN :'(
    June 6, 2016: IUI #2 w/Clomid - BFN :'(
    IVF Consult 1 & 2: June 10, 2016 / July 15, 2016 
    Started Stims: July 15, 2016 (Lupron, Gonal-F, and Menopur)
    Trigger ----> 08/03 ----> ER on 08/05 ----> Transfer ------> 08/10
    BETA 1 (8/22) - 401  - BETA 2 (8/24) - 541 - BETA 3 (8/26) - 913
    Baby Chadwell's First U/S: 09/06/2016 / EDD: 04/28/2017
  • @ddvj79 The side effects seem to be minimal for me, other than the occasional headache. Especially if I don't pay attention to my eating habits and make sure I don't get too hungry. Other than that it doesn't bother me.
    About us:
    Me - 28, Lean PCOS
    DH - 31
    Married June 2010, TTC since March 2014
    Blog: ourbinarystar.com

    FET cycle #3 Transfer July 28th 2016, Triplets born healthy on February 26th 2017 at 33w1d!

  • @ddvj79 I suffer from atypical migraines and the headaches were the only side effect I had. Sometimes it was just a dull constant pain and other times it was terrible! Unfortunately nothing I did took care of the headaches, but I'm doing a fresh transfer so as soon as I added in the stims (a week later) the headaches went away. I'm guessing it's 10 units. I started at 10 then went down to 5. Good luck! 
    TTC #1 since August 2013
    Unexplained/ Endo
    Medicated IUIs # 1-3 BFN
    IVF #1- BFN
    FET #1- BFP; Ectopic pregnancy found at 7wks
    FET #2- February 2017 BFP  Beta #1- 119 (8dp5dt) Beta #2- 475 (12dp5dt)
  • ddvj79ddvj79 member
    Thank you @AandSbaby  @AandDM2014 & @lilmissslp!

    I am trying to pay attention to my eating habits right now & hopefully avoiding my triggers will help.

    This evening will be my day 4 of Lupron, so far not too bad. I do have headaches & nausea but its almost like my baseline because of the number of migraines I get is between 3-5/week 
    Just hope it stays like this or gets better :) 

    DH :  36, has Chronic Kidney Disease, on dialysis & is waiting on the transplant list (average wait for B+ is 5 years)

    Me:   36, Hypothyroidism, PCOS, BMI 32, need to be done with "child bearing" ASAP so that I can be a Kidney donor (was fun realizing we didn't as much time as we thought :-/ )

    We're TTC#1

    IUI #1 : 5mcg Letrozole (CD 3-7) + Ovidrel Trigger + Had the one follicle = BFN  (March 2014)

    IUI #2 : 5mcg Letrozole (CD 3-7) + 150 iu Bravelle on CD9 (after much begging!) + Had the one follicle = BFN (April 2014)

    7th May 2014 - changed REs, this one seems to care (we think....)

    IUI #3 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 3 follicles (2 under 15mm) = BFN(May 2014)

    IUI #4 : 7mcg Letrozole (CD 3- 7) + 75 iu Bravelle (CD 8-12) + CD12 Scan 5/16 + Had 1 follicle + DH gave best sample so far = BFN(June 2014)

    IVF#1 -  ER Only Cycle Sept-Oct 2014, 17  eggs Retrieved, 14 mature, 10 fertilized, 6 made it to Blast & post PGS  5 were not viable due to chromosomal abnormalities
    Not sure where we go from here...

    We're parents to two very adorable, bratty, affectionate & goofy Bernese Mountain Dog pups who would very much like a 2 legged baby brother or sister of their own!

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