CoQ10 -- Ubiquinol? Dosage? Brand? Please Help! — The Bump
Infertility

CoQ10 -- Ubiquinol? Dosage? Brand? Please Help!

Hello! I am preparing for a new FET this fall and I wanted to start taking CoQ10, which my RE and a nurse from the insurance company both recommended. I went to buy a bottle today and was incredibly overwhelmed by all of the options! Does anyone have any advice on which brand to buy? Is Ubiquinol better than Ubiquinone? How much are you taking? (I was told 600 mg daily, but that seems like a lot!) And information you can share would be greatly appreciated! Thank you so much! 

Re: CoQ10 -- Ubiquinol? Dosage? Brand? Please Help!

  • I use costco brand CoQ10 300mg, one with breakfast one with dinner. Best price for my budget and there's a lot in a bottle :)
  • edited July 2016
    @Jewels292I was told by my RE (and I think others here have echoed) that the Ubiquinol is better for absorption. I bought these from Amazon and take one a day. I am obviously not an expert, but 600 mg seems like a lot.

    ETA link.

    ETA: this article actually says 600 mg is recommended, so now I am off to find out if I am taking too small of a dose. D'oh! It's so hard to keep up with it all sometimes.

    Me: 40, DH: 35 / Married: 2009; TTC #1: 2013

    2013 - 2015: 5 pregnancies —> 5 miscarriages

    TTCAL with RE (RPL specialist): February 2016

    2016: 3 medicated TI cycles —> 3 medicated IUI cycles: All BFN

    Donor Egg IVF Transfer: May 1, 2017

    May 11, 2017: BFP!! Beta #1: 449.1, Beta #2: 844, Beta #3: 1714

    EDD: 1/17/18, it's a GIRL!  <3 E. L. A. born 12/7/2017








  • Loading the player...
  • I have been taking the ubiquinol (active form) from Costco. The brand is Qunol. It's 100mg pills. It's more expensive than the regular CoQ10, but I figured it was worth it so I didn't have to take 400-600mg or like 3 pills of the regular coq10. It's also not that much $$ compared to all the other costs of treatment :0)
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • Thank you so much for your responses, @wintersong555, @fivetimesnoluck & @JamieH2000! There is almost TOO much information about this out there. It's so confusing!

    @JamieH2000 -- Are you just taking 1 100mg pill a day? 

    I just pulled this from the comments of that article:

     “The suggested daily dose of Ubiquinol for the average person is 100 mg per day. For those who are older, or suspect decreased levels of CoQ10 due to health issues, supplementation may be started at 200-300 mg per day for two weeks. After two weeks blood plasma levels plateau and dosage may be lowered to 100 mg per day, as maintenance.”

    So, I think I am leaning towards taking 100 mg per day of the Ubiquinol (I'm still a little confused, but think the 600 mg/day is the dosage for the Ubiquinone?)

    Still open to more advice if anyone has it! Thanks so much! 
    fivetimesnoluck
  • I take 200mg a day...I have to check my notes from the nurse when I get home, I'm nervous I should be taking more.  We took a while to decide if we were going to move forward with fertility treatments.  We are starting IUI this month...just as excited as I am anxious.  
  • @Jewels292 my RE recommended 300 mg ubiquinol or 600 mg of ubiquinone. I have also been taking the Qunol brand. Good luck! 
  • Yes I'm just taking 100mg right now, but was considering taking 200mg once I start stims since that's when I'll be needing lots of that cell energy to produce hopefully a lot of high quality eggs 
    History in Spoiler

    Age: 32 (same with DH). Together since 2006, Married June 2013 and TTC since August 2015
    Diagnosis: Mild Endo, DOR (AMH of 1.5), Poor Quality Eggs/embryos, Displaced Window of Implantation (ERA Post Receptive)
    March-May 2016: 1 TI and 2 IUIs- BFN 
    June 2016- Laproscopy- found/removed mild endo and confirmed only 1 normal healthy ovary.
    August 2016- IVF #1 with Antagonist Protocol- Cancelled (2 lead follies), converted to IUI- BFN
    Oct-Nov 2016- IVF #2 with Estrogen Priming Micro Lupron Protocol, 2 eggs retrieved, day 3 transfer of 1- BFN
    January 2017- New RE, IVF#3 with Estrogen Priming Antagonist Protocol, 12 eggs, 8 mature, 6 fertilized, 2 day 5 early blasts transferred (none to freeze :(), BFN
    May 2017- Sept 2017- Starting Donor Egg process! Waiting for donor to be available... and then she is pregnant at baseline :(
    Oct 2017- Donor #2: 25R, 22M,18F, 12 blasts frozen! Fresh transfer cancelled due to thin lining with fluid :(
    Nov 2017- Hysterscopy to remove polyp
    Dec 2017- DE FET #1 on 12/8 on 2 perfect blasts- BFN and devastated
    Jan-Mar 2018- ERA #1- Post receptive by 24 hours, ERA #2 RECEPTIVE with 4 days of Progesterone
    Apr 2018- DE FET cancelled for lining issues :(
    Jun 2018- DE FET #2 of two 1AA blasts- first BFP ever! Beta 10dp5dt- 378, Beta 14dp5dt- 2840, Beta 16dp5dt- 4035, beta 18dp5dt- 10916. Due on 2/20 with one baby after a vanishing twin
    Baby Born born early @ 33.5 weeks due to Pre-e
    Back for # 2!
  • @jewels292, can i ask why they recommended taking this supplement for an FET, doesn't it help with egg quality so what does it do once the embryo is already formed? Im just curious as im getting ready to prepare for another FET this fall and want to do everything i can. 

    Me (28) DH (32)
    Married: Dec 2011
    TTC#1 May 2014
    Dx: MFI (low count)
    FET#1 May 2016  BFP 
    EDD 2/4/17 - TWINS- MC July  o:)o:)
    FET#2- 11/9/16 BFP- MC o:)
    FET#3- 2/8/17 BFP- MC o:)

  • I take Ubiquinol 400 mg. per day. I also have MTHFR gene and that is why I take a little extra. I think 200 is what I hear the most. Oh, and I get the Vitamin Shop brand. 
    TTC Since July 2014.
    August 2015: Clomid, BFN
    September 2015: Clomid, BFN
    -October Switched to RE-
    November 2015: Clomid 100 MG, IUI , 2 eggs= BFN
    February 2016: Clomid 100 MG, Gonal F, 450, 3 eggs =BFN
    -Took a Break for a Cyst-
    March 2016- Clomid 50 MG, Gonal F, 2 eggs = BFN
    April- May took a much needed break!
    June 2016- 1st IVF Cycle= 2 Transferred, None to Freeze= BFN
    Sept. 2016- 2nd IVF w/planned FET November 16' (NEW Clinic)~
    MTHFR C6777 HET positive


    http://www.realinfertility.wordpress.com/

  • My RE just confirmed the exact same dose today.  Both myself and DH are going to take it.  There's a little MFI here.  

    Married: October 2014

    Me: 35 DH: 39

    TTC since November 2014

    Diagnosis: Anovulation from PCOSish without syndrome, Male factors - low motility and morphology issues

    April-Sept. 2015 - Clomid and TI - BFN

    Dec. 2015- HSG - Clear tubes

    Jan., Feb., March 2016 - Letrozole 7.5mg and TI with HCG trigger= BFN

    April, May, June 2016 - Letrozole 7.5mg and IUI with HCG trigger= BFN

    September 2016 - IVF round #1;ER 9/26 with ICSI on 14 eggs - developed mild OHSS. 

    Sept 2016 - 12 non-PGS embryos frozen (5 5AAs)

    FET #1 Jan 16, 2017 - BFP!- MC at 6W5d

    FET #2 May 8, 2017 - BFP! EDD 1-24-2018

  • 7Kaby7Kaby member
    Don't worry about whether you take ubiquinol or ubiquinone. They have the same potency and absorption. I have done a wealth of research and the ubiquinol manufacturer claims it is better based on their own research in the lab and in animals - not human studies. Also, ubiquinol is so unstable that by the time it reaches the intestines where it is absorbed, it has been converted to the oxidized ubiquinone. Honestly, there is no need to pay extra - spend the extra money on a higher quality ubiquinone instead. 
    We used a dose of 3x100mg of pharmaceutical-grade ubiquinone. In the past two miscarriages at 9 and 13 weeks. This time the CoQ10 made everything take and stick and we had a beautiful daughter in June. I am a believer in CoQ10. Used Bio-Quinone Gold, which was recommended initially for migraines by our family doctor. 
    I always believed that it pays off to buy a good and proven quality. And now that we have a beautiful daughter I wouldn't change a thing. Good luck and baby dust to you all - the CoQ10 market is a jungle
  • **pregnancy mentioned**

    I took Co-Q 10 prior to my IVF cycle two months ago - not sure if that is what did the trick or if it was due to other things but I wound up with 6 blastocysts (out of 8 fertilized eggs) and I am now 8 weeks pregnant with twins.  I focused really heavily on preparing my body in every possible way and CO-Q 10 was mentioned again and again as helpful for egg quality and fertility.

    After lots of research I went with ubiquinol - many sites and forums mentioned that this was a more bio-available version and while it is more expensive I figured I was spending so much money anyway a little extra wouldn't make a difference.  

    The brands I used were Jarrow and then later I switched to Now Foods (I'm not sure why I switched but I think there was something in the Jarrow brand I wasn't a fan of).  I went with the 200mg dosage and took two per day - studies showed that 600mg of ubiquinone were helpful and ubiquinol is about twice as potent as ubiquinone so I figured the equivalent of 800mg of ubiquinol would work.  

    I took it primarily to improve egg quality (I have endometriosis and a low amh) but it helps the energy level in all of your cells so I don't see why it couldnt help for a FET.  Wishing you all the best! :smiley:  
  • Hi @Jewels292 !

    I took CoQ10 for my 1st IVF cycle. I was told it helps with egg quality. Took 600mg daily - 2 300mg pills. Brand was Finest Nutrition (from Walgreens). They retrieved 21 mature eggs and all 21 fertilized! We ended up with 12 embryos, but one tested abnormal... so 11 total. I would say CoQ10 did the job well!

    As for using during FET cycle... I haven't heard anything about this (other than the posts above). My nurse/RE have not mentioned, and my FET is scheduled for next thurs 7/28. I will ask! Good luck!!
    *TW - Pregnancy mentioned*
    Me: 28 DH: 33, Married May 2014
    3 failed IUIs Dec '15 - Feb '16
    IVF April/May 2016 - 1 failed fresh transfer. 11 snow angels.
    1st FET 7/29/16 = BFP
    Lawson arrived on 4/24/2017 at 7lbs 15oz, 21 1/2 inches long!
    Surprise pregnancy!! Baby #2 due 10/11/18 <3
  • I also just started CoQ10 a little over a month ago to try and help egg quality also while we are taking a break from IVF. I'm on 100mg twice daily. 
    Me: 33, Hubby: 36
    TTC since May 2014
    First RE Appt - September 2015
    DX: Hypothyroid, DOR
    IUI w/ Clomid - October 2015 - BFN
    ER - 2/10/16, 2 Day 3 Embryos
    FET - 4/15/16 - BFN
    Summer 2016 - Taking a break to try herbal treatment and acupuncture
Sign In or Register to comment.
Choose Another Board
Search Boards