Community› The Bump Message Boards› Infertility
Infertility
New Discussion

PIO vs suppositories

lizmb-2lizmb-2 member
in Infertility
hey guys, I stated PIO injections last Tuesday. I had a fresh transfer this past Friday. Ever since I started my PIO injections I get an awful fever off and on (101-102.5) a couple hours after injection and the body aches and fever go away about 4 hours before my next shot the next day! It's awful! I've switched to a different oil based progesterone and it has still been the same. I want to do what is best for thes embryos during this 2ww but this fever is awful and probably not good for them either. 
The nurse is going to ask the Doctor if I can switch to the suppositories. I'm just concerned bc I've read about the suppositories not being as effective. Has anyone had a successful fresh cycle with suppositories? 

Ps: I've had a flu and strep test and both came back negative so I think I'm just extremely sensitive to these PIO injections. 
Report Reply to Post

Re: PIO vs suppositories

  • ale9687ale9687 member
    My friend who went to my RE is 3 months pregnant after a 5 day fresh transfer and she did the suppositories. I'll be starting my first round of IVF and am interested to see what they'll have me do. For IUI I took progesterone pills twice a day. 
    Report Reply
  • Loading the player...
  • lizmb-2lizmb-2 member
    Thank you @ale9687! That makes me feel better :) I'm going to give the suppositories a try! Good luck on your IVF round! FX you have a great cycle! :) 
    Report Reply
  • sleepyrnsleepyrn member
    I'll be doing a fresh transfer early June and they have me down for PIO every other night and suppositories on the days I don't do the PIO. 

    me:41 dh:42
    me:PCOS, blocked left fallopian tube, hyperprolactinemia  (dh's swimmers are perfect/normal)
    Tried 3 rounds of clomid with Ovidrel trigger (BFNs)
    May/June 2016 IVF   6/1 ER 7 eggs retrieved, 7 fertilized via ICSI  6 embryos made it to blasts.
    6/6 2 AA embryos transfered, 4 BBs frozen
    Beta 6/18  -- BFN
    FET #1 August 22 BFN
    Dec 2016/Jan 2017 Round 2 was a bust. 6 eggs, Only 1 embryo made it, no transfer
    FET #2 cancelled 10/17 due to uterine polyps. Postponed until 9/2018 due to hip replacement.

    FET #3 9/11/18 Uterine scratch and antihistamine protocol/lovenox done this time. 2 AA hatching blasts put in.  BFP 9/20/18!! 

    Report Reply
  • BingALing23BingALing23 member
    I did a fresh transfer (day 5) and they had me do PIO for 8 more days (day 13) after that I did Crinone.

     ***signature warning - child mentioned***

    Me:39 DH:31 Married June 2015

    Jan 2007 - laparoscopy: endometriosis fixed; BFP same month; DS born Nov 2007

    August 2009 - Clomid; BFP;DS born May 2010

    Both DS's from previous marriage

    TTC since April 2015

    Aug 2015 - Clomid (not monitored) - BFN

    Oct 2015 - met with RE; unexplained infertility 

    Nov 2015 - Clomid, IUI, BFN

    Dec 2015 - Clomid IUI, BFN

    Jan 2016 - Clomid IUI, BFN; discussed IVF

    Feb 2016 - HSG, Endo biopsy, Mock transfer; BCP's; biopsy abnormal - given antibiotics

    March 2016 - Endo biopsy - all clear; BCP, Lupron, Menopur, Follistim, Ovidrel; ER 3/31; ET 4/5 - 1 Day 5 hatching blast; BETA 4/13 - BFP!!!; 2nd BETA 4/15 - still looking good; 3rd Beta 4/22 - going strong; US 5/2



    Report Reply
  • dadezbombzdadezbombz member
    For my first ivf cycle,  I did the Crinone. Hateddd it.  2nd cycle,  the tablet suppositories.  Both failed cycles.  Now,  on FET had transfer today.  Have been doing the PIO shots, and yes they are TERRIBLE.  The soreness is a drag, and the actual oil is painful.  I can't say ive had your side effects,  but the suppositories didn't work well for me,  which is y my dr switched to the pio
    Report Reply
  • lizmb-2lizmb-2 member
    Thank y'all so much for your responses! It's nice to here the different things hs everyone has or is doing.
    Report Reply
Sign In or Register to comment.
Choose Another Board
Search Boards
"
"