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Spotting on Femara/Letrozole

hispenguinhispenguin member
in Infertility
I have taken 3 of 5 doses of Letrozole and have been responding well. Except I started spotting, and not just a little. 

I'm planning on calling the clinic first thing tomorrow when they open, but just was curious if anyone else has had a side effect like this. 
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Re: Spotting on Femara/Letrozole

  • pmjbpmjb member
    @hispenguin I never spotted while on letrozole but that doesn't mean that it's not a side effect.  Bes of 
    Married: July 2013
    Me: 33 DH: 34
    TTC since Oct 2014
    ME: PCOS not ovulating + low progesterone
    HSG = clear;     FSH + AMH = good
    DH: SA = normal
    Apr 2015 - Dec 2015 - Letrozole + Clomid with OBGYN
    Jan 2016 - Referral to RE 
    Mar 19/2016 - IUI #1 Letrozole + Gonal-F + Ovidrel + Progesterone = BFN
    Apr 2016 - Cyst found, on BCP for month
    May 18/2016 - IUI #2 Letrozole + Gonal-F + Ovidrel + Progesterone
    June 2/16 - BFP!!!!


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  • MrsM00re87MrsM00re87 member
    I am currently on my 1st cycle of letrozole. Did not experience any spotting, you should definitely ring the clinic and let them know. I know it works to lower estrogen levels initially maybe spotting from the low estrogen level? 
    Me:28 (PCOS, DOR), DH: 32 (low morphology)
    TTC since March 2012
    2013-2014 - 6 rounds of Clomid - BFNs
    3 failed IUIs in 2015
    October 2015 - wait listed for IVF #1
    IVF #1 March 2016 - bfn, zero frosties!
    Femara cycle 1 May 2016 - POAS starting May 21st / beta testing May 25th....



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