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What time of day for PIO?

vssbrmvssbrm member
in Infertility
Good evening ladies. Quick question, my calendar does not specify the time of day to do the PIO (IVF, transfer). We start tomorrow and I could kick myself for not checking earlier. I would imagine since they did not specify a time then it probably does not matter... Figured you all could help. TIA.
Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
Me: 32 (33 in May), Him: 37 (January)

DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?)  New RE has a plan!!
       Him: Minor Varicocele, low morphology, slightly low count

History:

Beta 5/9/2016 BFP!!
Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer. 

3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
Starting IVF Stims on +/- Feb 22, 2016
HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)

Switched clinics and now prepping for IVF in February / March

Fourth IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - December, 2015 - BFN
Third IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - November, 2015 - BFN
Second IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - September, 2015 - BFN
Started Prolactin Medication October 15 - Levels quickly regulated to with in normal range
First IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - August, 2015 - BFN
After no BFPs (ever) First RE/Urologist visit in Feb 2015
HSG w/ OB, 2014 = all clear
Trying to conceive since November 2012
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Re: What time of day for PIO?

  • vssbrmvssbrm member
    Thanks for all the help ladies. We did the first PIO shot tonight. It was not nearly as bad as I was thinking it was going to be. I have a feeling that in a few days I will be singing a different tune tho.
    Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
    Me: 32 (33 in May), Him: 37 (January)

    DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?)  New RE has a plan!!
           Him: Minor Varicocele, low morphology, slightly low count

    History:

    Beta 5/9/2016 BFP!!
    Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
    Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer. 

    3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
    Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
    Starting IVF Stims on +/- Feb 22, 2016
    HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)

    Switched clinics and now prepping for IVF in February / March

    Fourth IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - December, 2015 - BFN
    Third IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - November, 2015 - BFN
    Second IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - September, 2015 - BFN
    Started Prolactin Medication October 15 - Levels quickly regulated to with in normal range
    First IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - August, 2015 - BFN
    After no BFPs (ever) First RE/Urologist visit in Feb 2015
    HSG w/ OB, 2014 = all clear
    Trying to conceive since November 2012
    Report Reply
  • AandDM2014AandDM2014 member
    @vssbrm the first one is always the easiest! Luckily after about 2-3 weeks they generally get better.
    About us:
    Me - 28, Lean PCOS
    DH - 31
    Married June 2010, TTC since March 2014
    Blog: ourbinarystar.com

    FET cycle #3 Transfer July 28th 2016, Triplets born healthy on February 26th 2017 at 33w1d!

    Report Reply
  • Griffin5413Griffin5413 member
    My RE had us to POI in the am. Not sure if there was any reason for that but he was specific that it should be am for my FET. 
    Me: 33 (no known issues)
    DH: 33 (lower motility; 0 morphology)
    TTC since Oct 2013
    IVF round 1 January 2016 (w/ ICSI)
    ER: February 17, 2016; 15 eggs retrieved, 14 mature, 11 fertilized
    Day 5 Blastocysts: 8 sent for PGS - 5 Normal
    FET date: April 12, 2016 - DS born Dec 7, 2016
    IVF round 2: FET : Oct 4 - 1st Beta 188!



    BabyFruit Ticker
    Report Reply
  • AandDM2014AandDM2014 member
    @Griffin5413 How strange! When I asked my doc if I could do it anywhere other than my butt because DH was going to be at work during our shot window (and like 5 hours before and after), my nurses had me come in to the clinic so they could do it for me because they didn't want it done anywhere else. (I have since put on my big girl panties and can do it myself in my butt)
    About us:
    Me - 28, Lean PCOS
    DH - 31
    Married June 2010, TTC since March 2014
    Blog: ourbinarystar.com

    FET cycle #3 Transfer July 28th 2016, Triplets born healthy on February 26th 2017 at 33w1d!

    Report Reply
  • dragonfaeriedragonfaerie member
    They want me doing my PIO two hours before appointments, so mine will be in the morning once I start.

    ---Trigger warning---

    Me: 31 DH: 27
    TTC since April 2013
    Two cancelled IUIs in Aug and Sept '15 due to low motility/count
    IVF round 1: January 2016
    ER: February 17, 2016; 9 retrieved, 7 mature, 7 fertilized
    Day 5 Blastocysts: 5 BB, 1 AB, all normal from PGS
    FET date: May 11, '16; transferred 1 AB embryo
    First beta: May 23, '16: 998!!  Second: May 25, '16: 1648
    EDD: January 27, 2017
    BabyFruit Ticker
    Report Reply
  • Griffin5413Griffin5413 member
    AandDM2014  - I just re-read my post... I meant that I do my shot in the morning... not my arm... :smile: 
    Me: 33 (no known issues)
    DH: 33 (lower motility; 0 morphology)
    TTC since Oct 2013
    IVF round 1 January 2016 (w/ ICSI)
    ER: February 17, 2016; 15 eggs retrieved, 14 mature, 11 fertilized
    Day 5 Blastocysts: 8 sent for PGS - 5 Normal
    FET date: April 12, 2016 - DS born Dec 7, 2016
    IVF round 2: FET : Oct 4 - 1st Beta 188!



    BabyFruit Ticker
    Report Reply
  • AandDM2014AandDM2014 member
    @Griffin5413 Ah, that makes a bit more sense! I was super confused, especially since I had an IM shot in my arm two weeks ago.

    I think it probably depends on your clinic. Mine does blood draws in the morning, then calls in the afternoon with results, so when changes have to be made to medication they can be made that evening. I also find it easiest to do in the evening because I'm always awake between 6 and 8 pm. I'm not always awake between 6 and 8 am, so I'd have to adjust the meds every day.
    About us:
    Me - 28, Lean PCOS
    DH - 31
    Married June 2010, TTC since March 2014
    Blog: ourbinarystar.com

    FET cycle #3 Transfer July 28th 2016, Triplets born healthy on February 26th 2017 at 33w1d!

    Report Reply
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