Infertility

ANA positive and FSH high

This is a random question but it dawned on me after talking to a family member the other day...

a few few months ago I had some stomach issues and had an ANA panel done bc my family has a history of Lupus (mom, aunt and uncle). My ANA came up with a slight positive. I went to a rheumatologist and had a larger Lupus screening done and it came back negative but my ANA was positive again and a little higher than before. 

Anyways, I have a child from a previous marriage so was very surprised when my FSH recently was 15.5. I'm 31 and other than my high FSH my uterus etc looks good. Does anyone think my high FSH and positive ANA may be correlated? We're doing IVF/ICSI and starting injections next week but wondered if I should tell my RE about my ANA results from February. I didn't think about mentioning it to him until now.

Re: ANA positive and FSH high

  • I have no experience with either of these, but I would imagine any information about your health that you provide to your RE can only be helpful.
    Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
    Me: 32 (33 in May), Him: 37 (January)

    DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?)  New RE has a plan!!
           Him: Minor Varicocele, low morphology, slightly low count

    History:

    Beta 5/9/2016 BFP!!
    Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
    Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer. 

    3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
    Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
    Starting IVF Stims on +/- Feb 22, 2016
    HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)

    Switched clinics and now prepping for IVF in February / March

    Fourth IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - December, 2015 - BFN
    Third IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - November, 2015 - BFN
    Second IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - September, 2015 - BFN
    Started Prolactin Medication October 15 - Levels quickly regulated to with in normal range
    First IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - August, 2015 - BFN
    After no BFPs (ever) First RE/Urologist visit in Feb 2015
    HSG w/ OB, 2014 = all clear
    Trying to conceive since November 2012
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  • I would tell him but not sure they affect one another. You sound like me. I also have a high fsh (16) and I have a positive Ana (was also checked seriously for lupus just due to blood results I had no symptoms and they said I don't have it but I just have a positive Ana ). My RE didn't seem concerned about any of the rheumatologist stuff I guess because all the blood clotting stuff came back clear. I'm a bit older than you but not much. I'm 33. We did ivf/icsi as well and got 3 eggs at our retrieval, not much but we did mini stim so weren't expecting tons with my numbers. We had 1 make it to day 5 and froze it and transferred it back in early March. 

  • @rachlee2010 it's nice to hear someone in the same or similar situation. I'm so excited and nervous all at the same time. I hope everything went well for you! :) 
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