Infertility

Abd Pain with Provera/Metformin

I am having severe abdominal pains after taking Provera and Metformin for 4 days.  I am taking it with food (lunchtime) and then by the time I eat supper every night I start having intense cramping and gas pains(?).  I am able to have BM which makes it feel better.  Is this a normal side effect for these medicines?

Re: Abd Pain with Provera/Metformin

  • I've always had stomach discomfort with the metformin. So they switched me to the extended release. I have 1000mg in the am and pm. But until your body gets used to that medicine it can cause you to not feel 100%. But that should pass within a few weeks. 
    Married for 3 years
    Me: 28 DH: 33
    Together for a total of 6 years
    Fur mommy to two rescue dogs
    DX: PCOS and Insulin Resistance

    History:
    Irregular Cycles
    2010: Laproscopy with Hystroscopy ablation. Tubes were clear.
    1/5/2016 : DH sperm analysis is excellent.
    February: Switched to a new RE
    Two failed clomid rounds
    March 2016: New HSG and found tubes are open
    April 2016: Round one Letrozole 2.5 mg. Ultrasounds day 13 &16. No follicle grouth
    May 2016: Had to take a month off
    June 9th 2016: Started Letrozole again but at 5mg
    July 5th: bfp beta 31
    July 7th: Beta 97
    July 9th: Beta 231
    July 11th: Beta 500
    July 13: Beta 1400
    Beautiful son born 3/16/17 @ 1:38pm




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  • I hope it goes away soon!  This morning taking my stepson to school I had abdominal pain and severe nausea.  I had to go back home and sleep for a little while before making it to work by 10:30 :neutral: 
  • Met always causes stomach pain (gas etc) for me (right before a bowel movement)...and a ton more bowel movements...and there is a lot of urgency-like dude this could come pouring out of me at any second sorta situations. I felt the same symptoms at 1000 as I do at 2000 (and I have been taking it now for over a year). I find that I try to do little tricks to help. Like eating food in the morning when I take the 2 tablets and then taking the other 2 right before bed. Those seem to help. On a good day I will feel great and not have many symptoms on a bad day I wouldn't want to be far from a restroom and my tummy can hurt a lot! 

    It can also cause a lot of nausea and almost dizziness for me. 

    They say to watch what you eat with it...less fat etc. 

    For some people as they get accustomed to the drug the symptoms go away..and some people don't have symptoms to start. 

    I took off for a month of Met when we had a cycle cancelled due to no mature follies (we were going out of town for a week and because we couldn't do a 2nd ultrasound had to cancel we might not have had to cancel otherwise) and then went to the dr the next month after taking the cycle off from all meds (GOSH I FELT AMAZING!!) and found out I didn't have mature follies and the dr decided the only thing that might have caused no mature follies that time was not having my Met mixed with Fermera/Leterzole. This cycle I did all of it plus some and had a 27 folli!!! :) So I might hate the Met but it sure seems worth it! 
    Me: 37 DH: 32 TTGP Since 2014 INFERTILITY INFO (Medicated, IUI's, IVF/FET) IN SPOILER
    October 2014-April 2015: Without Medication or Doctor Guidance No Periods/No O BFN 
    Medicated April-December 2015: Clomid (didn't work) and so we tried Femera/Letrozole. Progesterone Met 1000 Not diagnosed PCOS but treating the same. Anovulatory. TI No US No O BFN 

    - TW - 
    IUI"S 
    January 2016-October 2016: Letrozole 2.5mg-7.5 mg, Pregyl or Ovideral Trigger Shot.
    9 cycles of IUI
    (7 Cancelled due to no mature follicles) (2 attempted IUI's with mature follicles)  

    IUI # 2 June 2016 and July 2016:  Met 1000, Estrogen (21 days), Progesterone (5 days) Femera 5m 6/28/16 Ultrasound CD14 = 25 follie. Pregnyl Trigger CD14 IUI 7/13 1stBeta (DPO 15): 7.6 (Surprise BFP...but Low #'s) 2ndBeta (DPO 17): 18 3rdBeta (DPO 19) 52.8 Progesterone Prescribed (spotting) 4thBeta (DPO 26) 6.9 Chemical Pregnancy BFN

    IVF and FET (diagnosed with PCOS) 204 pounds at start of IVF
    IVF # 1 October and November 2016: CCRM - Minneapolis 10/14 Consult and CD 3 testing, 10/14 started (OCP Antagonist - BCP) BCP, 10/21 1 day work up, Doxycycline 100mg 10 days, 10/24 stop bcp, Bloodwork US 10/29, 10/30-11/8 Stims 2 vials of Menopur, Dexamethasone, 225 of Gonal-F daily (dropped to 120). CCRM Vitamin Cocktail (like 20 of them), Monitoring (11/2, 11/4, 11/5, 11/6, 11/7, 11/8), Retrieval 11/10 (38 eggs, 30 mature, 16 fertilized ICSI), 11/16 8 Blasts 11/30 CCS testing results 3 Normal 5aa's (2 boys and 1 girl) 1 Unknown 4 Abnormal (All girls) 


    Fet #1 January 2017: CCRM - Minneapolis bcp/lupron/suppository/p4 in oil QOD AF 12/7, 12/8 start meds. 1/3 lining and blood work check 14/15 mm, BW check 1/6. 1/9 transfer with acupuncture 1 CCS/PGS Normal 5aa hatching Progesterone around 26ish? Lower estrogen level 207 (wanted above 300 but over 200 was acceptable), started 1 estrace, progesterone in oil every other day, vivelle dot patches 4 every other day, 3x estrodiol daily, vitamin cocktail. POAS: - 4dp5dt and 5dp5dt, 6dp5dt frer very very very faint line. 7dp5dt and 8dp5dt + on Accuclear. 8dp5dt pregnant on a clear blue easy digital. 214 pounds at FET
    1/18 #1 Beta 91.1
    1/20 #2 Beta 215.9
    2/3 6 week US 2 sacs? Twins? but only 1 heartbeat/pole good heartbeat Stopped taking baby asprin Added in DHEA Veg Vitamin (also got the report that they transferred a girl 5aa eggo) 
    2/10 7 week US 2 sacs (likely vanishing twin) only 1 heartbeat/pole etc good heartbeat 137
    2/24 9 week US 1 eggo sac good heart beat 182 1 very small fluid sac (shrinking) 
    2/24 9 week 2 days start weening. Graduated from RE (CCRM is now starting weening as soon as 8.5 weeks)
    3/7 10 Weeks 5 days  weened completely of FET meds A1C 5.3% (Normal)
    3/9 11 Weeks 1 day my progesterone level was 15 and my estrogen level was 881 (I freaked out!)
    3/16 12 Weeks 1 day baby heard on doppler 164 HB
    4/14 16 week 2 days Ultrasound baby is looking good with all good numbers sized 17 weeks. Also got to hear her on the doppler for a few mins too. 

    5/5 19 Weeks 2 days going in for "20" week anatomy ultrasound got measurements but need to come back as wasn't able to get all the measurements
    MEASUREMENTS BPD 4.6 cm 19 weeks 6 days* (78%) HC 17.0 cm 19 weeks 4 days* (70%) AC 14.5 cm 19 weeks 4 days* (69%) Femur 3.1 cm 19 weeks 6 days* (63%) Humerus 3.1 cm 20 weeks 2 days (84%) Cerebellum 2.0 cm 19 weeks 5 days
    CisternaMagna 6.2 mm Nuchal Fold 4.5 mm
    HC/AC 1.17 FL/AC 0.22 FL/BPD 0.68 EFW (Ac/Fl/Hc) 309 grams - 0 lbs 11 oz
    THE AVERAGE GESTATIONAL AGE is 19 weeks 5 days +/- 10 days.

    6/9 24 Weeks 2 days Glucose Test 1 hour (Failed) 190
    6/16 25 Weeks 2 days Ultrasound and 1st Baby Shower 
    6/20 25 Weeks 6 days Glucose Test 3 Hours (Failed) 95 (95), 183 (180), 213 (155), 198 (140) etc
    6/21 26 Weeks Recommended to a perintologist
    6/22 26 Weeks 1 day start monitoring blood sugar levels 
    6/30 27 Weeks 2 day A1 (blood sugar test ordered)

    7/5 28 Weeks Echo and 3d Ultrasound
    AMNIOTIC FLUID Q1: 2.6 Q2: 3.2 Q3: 4.8 Q4: 5.6 AFI Total = 16.3 cm Amniotic Fluid: Normal 
    MEASUREMENTS BPD 7.2 cm 28 weeks 5 days* (60%) HC 26.4 cm 28 weeks 4 days* (48%) AC 23.3 cm 27 weeks 4 days* (36%) Femur 5.2 cm 28 weeks 0 days* (36%) Humerus 4.8 cm 28 weeks 0 days (49%)
    HC/AC 1.13 FL/AC 0.23 FL/BPD 0.73 Ceph Index 0.77 EFW (Ac/Fl/Hc) 1142 grams - 2 lbs 8 oz (37%)
    THE AVERAGE GESTATIONAL AGE is 28 weeks 1 day +/- 14 days.

    7/10 28 Weeks 5 days Dietitian Appt and Lactatcian Consultant and A1 blood draw 5.4% (normal) 218.5 pounds
    7/20 30 Weeks GD consult. 6 Lantus at 7pm daily. Novolog 1 unit for every 15 gm carbohydrate if consumed more than 30 gm at brkfst or 60 gm at lunch or supper 215.6 pounds
    7/20 30 Weeks Transferred care to OB due to high risk. 216 pounds

    8/2 32 Weeks Ultrasound (not cooperative and still breech) and then weekly NST's
    MEASUREMENTS BPD 8.0 cm 32 weeks 2 days* (44%) HC 29.2 cm 31 weeks 6 days* (22%) AC 26.9 cm 31 weeks 0 days* (24%)  Femur 6.3 cm 32 weeks 2 days* (57%) Humerus 5.7 cm 32 weeks 6 days (71%)
    HC/AC 1.08 FL/AC 0.23 FL/BPD 0.78 Ceph Index 0.78 EFW (Ac/Fl/Hc) 1808 grams - 3 lbs 15 oz (29%)
    THE AVERAGE GESTATIONAL AGE is 31 weeks 6 days +/- 18 days.
    AMNIOTIC FLUID Q1: 3.4 Q2: 2.9 Q3: 2.9 Q4: 4.4 AFI Total = 13.6 cm Amniotic Fluid: Normal

    8/8 32w6d upped to 1:10 for dinner 
    8/11 Baby Shower
    8/13 Baby Shower
    8/16 34 weeks NST good reading Upped to 8 at bed for fasting and 1:7 for dinner 
    8/18 Dr Appt

    8/24 35 weeks 1 day (was suppose to be scheduled for 36 weeks) Weeks Ultrasound/GD Dr Appt/OB Appt 
    Frank Breech
    MEASUREMENTS BPD 8.9 cm 35 weeks 6 days* (67%) HC 31.7 cm 35 weeks 1 day * (35%) AC 30.2 cm 34 weeks 2 days* (33%) Femur 6.9 cm 34 weeks 6 days* (57%) Humerus 6.0 cm 34 weeks 6 days (64%)
    HC/AC 1.05 FL/AC 0.23 FL/BPD 0.78 Ceph Index 0.80 EFW (Ac/Fl/Hc) 2494 grams - 5 lbs 8 oz (39%)
    THE AVERAGE GESTATIONAL AGE is 35 weeks 1 day +/- 21 days.
    AMNIOTIC FLUID Q1: 3.3 Q2: 3.8 Q3: 2.4 Q4: 3.8 AFI Total = 13.4 cm Amniotic Fluid: Normal

    8/31 36 Weeks
    9/7 37 Weeks
    9/10 Water broke...I got it tested at the emergency room it it showed it was negative. More water breaking and didn't go to the dr.
    9/11 37 weeks 4 days Called the Dr and got retested for water breaking...
    10:30pmish Baby Girl Born via Emergency C Section (Frank Breech Baby) 6lbs 3oz  -
    9/13 Dropped to 5 pounds 10oz and had jaundice 
    9/13 38 weeks

    9/22 39 Weeks 2 days C Section Scheduled for 10am (arrive at 8am) Equinox/Solstice
    EDD 9/27
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