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Successful IVF with severe MFI?

GarnerWifeGarnerWife member
in Infertility
hi Ladies, I'm looking for some hope.

We had 2 SA's come back with 0.1/0.2 million sperm/ml. Not good. We're waiting to see a urologist but assuming they'll send us straight to IVF with ICSI. I'm reading horror stories of very low fertilization rates with such a low sperm count and I'm wondering if anyone has been in a situation like this. Luckily everything checks out fine with me, it's just DH who has issues. We're in our mid 30's.

He's started ubiqinol and Fertilaid but I'm not hopefully it will make much of a change because the numbers are so low.

please share any positive stories! We are so saddened by this.
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Re: Successful IVF with severe MFI?

  • wifeinraleigh28wifeinraleigh28 member
    I'm sorry about those results @GarnerWife.  I would recommend that you post this in the Success after IF or Pregnant after IF boards since most of the folks on this board haven't seen success yet.  I do know that IVF is successful with severe MFI though.  In fact, it is the only treatment that can see success with severe MFI.  I've heard stories of IVF being successful even with needing to surgically extract sperm due to blockages where there is zero sperm in the ejaculate.  Don't lose hope because it is possible.  In IVF they only need 1 healthy sperm cell per egg that they fertilize!

    You will find a lot of support in this community if you decide to stick around.  Welcome!
    ***BFP & Child Warning***

    Me: 34, DH: 38 ~ TTC since 2014
    IUI #1-3 (Nov 2015, Feb 2016, May 2016) = BFNs
    IVF ER (July 2016) = 7 PGS normal embryos
    FET #1 (Sept 2016) = BFP! DD born 5/30/17
    FET #2 (April 2019) = BFN
    FET #3 (July 2019) = BFP! DS born 3/27/20
    Report Reply
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  • GarnerWifeGarnerWife member
    Thanks for encouragement! I will post on the other board too, I appreciate it.
    Report Reply
  • oxinfreeoxinfree member
    ***trigger warning***
    Hey @GarnerWife - yes, other boards will be better suited to this question, however, a good friend of mine's DH has azoospermia. She got pregnant first try IVF with ICSI for both her DS and DD. Best of luck to you. Don't lose hope. Focus on what you can control and that is a positive mindset! ;) xx
    ---
    Started TTC April 2011
    Me: 32, DH: 32
    Diagnosis: Endometriosis

    • 2012 - 3 Rounds clomid - all BFN
    • 2013 - 1 Fresh IVF with 2 day 3 embryos - BFN
    • 2014 - 1 Frozen IVF with 2 day 5 embryos - BFN
    • Took a long break, continuing trying naturally
    • Feb 2016 - Biopsy = Endo, DH sperm improved from 1% to 6% morphology
    • March 2016 - Fresh IVF cycle with acupuncture & intralipids: 20 eggs retrieved (17 mature), 7 ICSI'd fertilized, 9 naturally fertilized. 16 total embryos!
    • April 8th - 2 embryos (1ICSI and 1 Natural) transferred. (7 blastocysts frozen), April 18th - Beta = BFN
    • Sept 23rd - Lupron Depot Injection for Endo control
    • Nov 15th 2016 - Started daily Lupron Injections for upcoming FET
    • Nov 22 - Baseline US/BW - Intralipid Infusion - Start Meds for FET with immune protocol
    • Dec 16th FET transfer of 3 embryos (1 - AA, 2 - BB)
    • TW below
    • Dec 22nd - first ever bfp (very faint lines FRER & cheapie)
    • Dec 27th Beta = 192, Dec 29th Beta = 379
    • EDD - Sept 5th 2017

    - - -
    I'm a YouTube vlogger who talks about Infertility, IVF and Endometriosis. Check it out here!
    Follow along at http://liv4today.blog
    Instagram @liv4todayvlog 


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  • dragonfaeriedragonfaerie member
    @GarnerWife My DH had very low count and motility (can't remember his exact numbers, but it was less than a million after wash) and we had 6 eggs fertilize using ICSI. It can happen!!

    ---Trigger warning---

    Me: 31 DH: 27
    TTC since April 2013
    Two cancelled IUIs in Aug and Sept '15 due to low motility/count
    IVF round 1: January 2016
    ER: February 17, 2016; 9 retrieved, 7 mature, 7 fertilized
    Day 5 Blastocysts: 5 BB, 1 AB, all normal from PGS
    FET date: May 11, '16; transferred 1 AB embryo
    First beta: May 23, '16: 998!!  Second: May 25, '16: 1648
    EDD: January 27, 2017
    BabyFruit Ticker
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  • caitiemaecaitiemae member
    My husband is one of those guys with azoospermia and had to have sperm surgically aspirated. The procedure wasn't nearly as successful as we had hoped for and just had 15 (yes double digits) leftover after ICSI. Good news though, 7 out if 8 eggs were fertilized and 4 made it to blasts! Best of luck with IVF and stay positive!
    ***pregnancy mentioned***

    Me: 27/ DH: 29
    Dx:  obstructive azoospermia 
    IVF#1:  October 2015
    10/7/2015:  ER  11 retrieved, 8 mature, 7 fertilized w/ ICSI
    10/12/2015:  Transferred 5AA and 4AA blasts, froze one 4AA and 4BB
    Beta #1 9dp5dt:  122!!! BFP!
    Singleton, due June 2016

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  • flanners1flanners1 member
    Same here @GarnerWife my DH had very poor sperm count and bad motility but we still had 28 fertilised eggs (I have PCOS on top of his issues, hence so many eggs) of which 18 made it to 5day blastocytes and 11 made it through PGS. 
    Im sorry you have to go through this, but I have seen many success stories here from people with the same or similar issues, so don't give up hope. Fx 
    Me: 38, DH: 40 living in Asia
    TTC since March 2015 with known PCOS and MIF
    IVF in 2015. FET nr 3 in 2016 - BFP. Healthy baby girl born in April 2017.
    Trying for nr 2

    Report Reply
  • ekc0630ekc0630 member
    ***WARNING****
    My DH had very bad SA.  Everything was low.  We tried 6 unsuccessful IUI's.  We did 2 IVF.  Both had a low number of fertilized eggs but my AMH was also low.  Our second IVF was successful.  Good luck to you!
    TTC 2007
    Me-OK DH- MFI
    2010 IUI 1-3 Femara + Ovidrill BFN
    Change DR 5/12 IUI 4-5 Natural Cycle BFN
    5/13 DH diagnosed with b1/b3 microdeletion of Y chromosome
    IVF #1 July  Started Lupron 7/5 AF 7/14
    ER 8/1 7R 5M 3F W/ICSI ET 8/6 Moved to 8/7 due to no blast 
    Transferred our UNO embryo Beta #1 27 Beta #2 33 Beta #3 29 CP :(
    IVF #2 Started Lupron 2/14 
    Protocol 10U Lupron, 150 Bravelle, 150 Menopur, HGH for 4 days, Dexamethesone, 
    Supplements 6000mg CoQ10, 100mg DHEA, Vitamin D, Folic Acid, 
    ER 3/12 8R 4 able to be injected 2f with ICSI ET 3/15 2 "perfect" textbook Embryos
    2 crinone, estrace, dexamethesone, doxycycline
    BETA #1 3/26 201  BETA #2 3/28 524  BETA #3 4/5 9,876  Ultrasound April 7 Showed TWINs
    April 18 ultrasound Baby A HB 147   Baby B HB 146  Both measuring 7w1d
    WE ARE TEAM BLUE X2!
    Jonathan Daniel received his angel wings July 23, 2014 :( born 9/20/14
    Jackson Thomas was born October 31, 2014 @ 35w 5d
    image



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  • chickyclgchickyclg member
    We had success DH's main issue was Morphology and I also have a low AMH.  IVF/ICSI  was our protocol. 

    ~~~~~~~~~Siggy Warning~~~~~~~~

    Me~28 DH~27 

     6-12-2010  Miscarriage. 
    3-16-2012 D&C/Miscarriage.
     Blocked Left Tube. 
    Diminished Ovarian Reserve   
    MFI - Sperm Morphology 2%.  
    MTHFR 
     Abnormal Antiphospholipid Antibodies
    April 2013 ~  1st IUI attempt - 100 mg Clomid- Canceled
    May 2013  ~ 2nd IUI attempt -100 mg Clomid- Canceled
    June 2013 ~ 3rd IUI attempt - 100 mg Clomid+ Trigger+ Progesterone~BFN
     IVF/ICSI #1 May 2014 ~ Freeze All ~ Due to OHSS
     5/1/2014 ~ 22 retrieved, 12 fertilized, 3 frozen
    5/28/2014 ~ FET#1 ~ Transferred 2 Hatching Blasts
      6/1/2014~ **BFP**
    6/9/2014 Beta #1 ~ 1022
    6/12/2014 Beta #2 ~ 3099
    6/16/2014 Beta #3 ~ >5000
    6/19/2014 First U/S ~ TWINS!!!  
    1/7/2015 Twins born @ 34 weeks

    image image Image and video hosting by TinyPic



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