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First cycle with Prometrium & stressing out

LizzieJ13LizzieJ13 member
in Infertility
OK, so I'm 15 dpo and getting BFNs but no sign of AF (usually arrives at 14dpo). Since I'm on progesterone supplements, I'm 99% sure I'm not pregnant. I really don't want to take another pill tonight because I'd like AF to start soon, but should I continue for a few more days/get a beta? We have plans to travel over Easter but if I don't get my period by Wednesday, we can't, because I'll have to go for an ultrasound during the time we'd be gone.

My plan right now is to take a pill tonight, skip tomorrow morning's and call my RE first thing to see what she advises (and take the pill ASAP if need be). Anyway, I know TTC is more important than our travel plans, but I'm trying to balance the two. My Google searches seem to indicate a pretty even split between women who get their period while on progesterone and those who need to stop it for AF to show. I can't remember what the nurse told me to do (note to self: write these things down) and I'm stressed tonight!!
Me: 33, PCOS with anovulation
DH: 36, No known issues
TTC since 11/2014
1000mg Metformin daily

Oct-Dec 2015: Letrozole 5mg, Ovidrel, TI = BFN x 2
Feb-May 2016: Letrozole 5mg, Ovidrel, TI, Prometrium = BFN x 3
August 2016: Clomid 100mg no response, Letrozole 5mg, Ovidrel, TI, Prometrium = BFN

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Re: First cycle with Prometrium & stressing out

  • vssbrmvssbrm member
    I was always a few days late with supplemental progesterone. Your plan to call the doctor in the morning sounds like a good one! My fx that it's not the prometrium but a BFP.
    Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
    Me: 32 (33 in May), Him: 37 (January)

    DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?)  New RE has a plan!!
           Him: Minor Varicocele, low morphology, slightly low count

    History:

    Beta 5/9/2016 BFP!!
    Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
    Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer. 

    3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
    Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
    Starting IVF Stims on +/- Feb 22, 2016
    HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)

    Switched clinics and now prepping for IVF in February / March

    Fourth IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - December, 2015 - BFN
    Third IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - November, 2015 - BFN
    Second IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - September, 2015 - BFN
    Started Prolactin Medication October 15 - Levels quickly regulated to with in normal range
    First IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - August, 2015 - BFN
    After no BFPs (ever) First RE/Urologist visit in Feb 2015
    HSG w/ OB, 2014 = all clear
    Trying to conceive since November 2012
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  • wifeinraleigh28wifeinraleigh28 member
    My RE always instructs me to stop progesterone on 14dpo if I get a BFN on HPT.  Progesterone has never delayed my period but I know that it can do this.  If you are getting BFNs it is probably a good time to stop the progesterone but you should always follow your doctor's instructions!
    ***BFP & Child Warning***

    Me: 34, DH: 38 ~ TTC since 2014
    IUI #1-3 (Nov 2015, Feb 2016, May 2016) = BFNs
    IVF ER (July 2016) = 7 PGS normal embryos
    FET #1 (Sept 2016) = BFP! DD born 5/30/17
    FET #2 (April 2019) = BFN
    FET #3 (July 2019) = BFP! DS born 3/27/20
    Report Reply
  • LizzieJ13LizzieJ13 member
    Thanks @vssbrm and @wifeinraleigh28 . My RE's office confirmed that it was fine to stop it after my BFNs. The nurse said it could take up to a week to get my period - I either want it to start like, right now OR hold off for a full week so we can go away on Easter weekend!
    Me: 33, PCOS with anovulation
    DH: 36, No known issues
    TTC since 11/2014
    1000mg Metformin daily

    Oct-Dec 2015: Letrozole 5mg, Ovidrel, TI = BFN x 2
    Feb-May 2016: Letrozole 5mg, Ovidrel, TI, Prometrium = BFN x 3
    August 2016: Clomid 100mg no response, Letrozole 5mg, Ovidrel, TI, Prometrium = BFN

    Report Reply
  • wifeinraleigh28wifeinraleigh28 member
    Sorry about your BFNs :(  I know it never gets easier!!
    ***BFP & Child Warning***

    Me: 34, DH: 38 ~ TTC since 2014
    IUI #1-3 (Nov 2015, Feb 2016, May 2016) = BFNs
    IVF ER (July 2016) = 7 PGS normal embryos
    FET #1 (Sept 2016) = BFP! DD born 5/30/17
    FET #2 (April 2019) = BFN
    FET #3 (July 2019) = BFP! DS born 3/27/20
    Report Reply
  • LizzieJ13LizzieJ13 member
    Thanks so much @wifeinraleigh28 - definitely gets harder each time!
    Me: 33, PCOS with anovulation
    DH: 36, No known issues
    TTC since 11/2014
    1000mg Metformin daily

    Oct-Dec 2015: Letrozole 5mg, Ovidrel, TI = BFN x 2
    Feb-May 2016: Letrozole 5mg, Ovidrel, TI, Prometrium = BFN x 3
    August 2016: Clomid 100mg no response, Letrozole 5mg, Ovidrel, TI, Prometrium = BFN

    Report Reply
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