3rd Trimester

Makena Progesterone Shots?

Hello all -

Almost 12 weeks and my OB suggested Makena progesterone shots starting around 16 wks - our first was born early at 35 weeks and 5 days.  We are right on the cusp of needing them I guess. I wondered if anyone had feedback on them (I will post in 0-3 mos. too).  I've started to do some research and found a few things but so far have the following questions (answer one or any:)): 
1. Have you found this shot to significantly alter your outlook i.e. cause depression or mood swings (worse than you expect in pregnancy of course LOL ).
2. When did you start/when will you stop the shot?
3. Has anyone heard that this shot can cause prolonged labor and extremely slow dilation after you stop taking the shot? I read of people going into labor about 7-10 days after stopping the shot.
4. Have you found the shot to cause significant weight gain?

I've tried to limit the things I take during pregnancy (really I haven't even taken Tylenol) so I'm feeling a bit lost and trying to do my research..  Thanks for any thoughts/guidance you have on this. 

Amanda

Re: Makena Progesterone Shots?

  • Sarcasm101Sarcasm101 member
    edited January 2016

    Hello,

    I take makena shots, (and I know there was a relatively recent thread on 2 tri about this). https://forums.thebump.com/discussion/12650969/has-anyone-else-had-progesterone-shots#latest

     I started taking the shots at 18 weeks because my first LO was born at 33 weeks. I should have started the shots at 16 weeks but I had issues with makena/ insurance that caused the delay. (you can start the shots as late as 21 weeks and take them until 36 weeks.

    I have not had any side effects to speak of. I have gained a little bit less weight than I did last time and haven't noticed any changes in mental status. They only "side effect" is minor injection sight pain for about 24 hours after my shot. It is worse at night because I sleep on my side, right where the shot went in.

    I was told by my doctor that once you stop taking the shots, to expect to go into labor in the next few days. I am obviously not there yet, so I cant speak to how the shots effect labor.

    I will say that Makena is a pain in the ass to work with. They don't make anything easy. However, my doctor told me to ask for financial assistance, whether you need it or not. Because they will always give you come kind of discount.

    FWIW, taking these shots is completely worth the hassle. The risks are very, very minimal. And I will do anything to avoid the NICU this time around.

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  • I have been taking these shots since 16 weeks- and I will be 33 weeks tomorrow.  I had my preemie at 32 weeks, so I say they have worked for me!  I started out with no problems, but now my right booty cheek gets a small red raised bump from the shot (the left doesn't lol).  I think the nurse was not hitting the right spot with them on that side. 

    I didn't have a problem working with the company, either.  But that all depends on your insurance.  My mail-order pharmacy works in conjunction with the Makena mail order pharmacy, so I really haven't had any problems with getting my medicine.  The only issue I had was over the Christmas/New Year holiday when they never called me to schedule my refill, which I needed them to so they can send it to my doctor's office.  I couldn't find the phone number (its a different number than my pharmacy). I had an hour long run-around but finally got ahold of someone who could help me and we got it taken care of. 

    My doctor last week told me that his last patient who finished the shots made it to almost 39 weeks before delivering.  I hope I can make it that long too!

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  • I have been on the shots since I was 16 weeks, currently 35. Previous delivered my first at 25 weeks. So go make it this far is great! I'm allergic to progesterone (which is extremely rare) so I had rare reactions to it but still took it, my doctor and I decided to stop it this week at 35 instead of 36 because of my allergy. I have not had any mental status changes or any extreme weight gain with it.
    I also started preterm labor a week ago and was placed on a different medication to slow the process.
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