For those on progesterone...

jen mayhill · January 2016

Hi Ladies,

I have been taking 200 mg(?) of progesterone suppositories for approximately 4 weeks (I am 10 wk 3d). I have noticed a few things that seemed strange, and wondered if anyone was experiencing these symptoms (or lack there of):

About 1-2 days per week, I feel menstrual-like cramps (not unbearable, but definitely noticeable). It tends to migrate to my lower back. I know this is common in pregnancy, but I had assumed it would improve when taking the suppositories. Anyone else?

I have had tender breasts since the moment I found out I was pregnant. The tenderness increased when I started the suppositories. Two days ago, the tenderness disappeared. My overall symptoms tend to wax/wane, but this was surprising since this has been the constant. Anyone else?

Of course I am fearing the worst...I am just not sure how I would know if something was truly wrong. I keep reading (Google...big mistake) that when taking progesterone, your body will prevent you from bleeding. Silly question, but would you call your doctor for the two items mentioned above?

Thanks so much in advance

mouse1029 · January 2016

Sounds less like something the progesterone is doing and more regular pregnancy symptoms/ lack there of. I was on progesterone and had all those symptoms but they were all considered regular pregnancy symptoms. I'm not on progesterone this time and have the symptoms.

nonniebird · January 2016

I'm also on progesterone. I haven't experienced cramps, so I can't speak to that, but I have had no breast tenderness the whole time I've been pregnant (I'm 8.3w.) Which I thought was weird because I thought that being on extra progesterone would make my breasts more tender. I saw my midwife yesterday who assured me that that was within the realm of normal. Also I had an ultrasound yesterday and all was looking good, and we heard the heartbeat.

I'm not sure you need to be worried, but if you would feel better I would just go ahead and call your provider.

bsckgb7 · January 2016

Progesterone tends to exacerbate pregnancy symptoms (I was on it after IUIs). However, my apps say around 8-10 weeks, the Placenta starts taking over and the hormonal toll on you should be less. So maybe that explains the increase in symptoms, but then the now decrease.

smilormarie · January 2016

Figured I'd tack onto this thread instead of starting a new one but get ready for some TMI:

My fertility doc had prescribed crinone 8% applicators similar to a tampon for my first round of clomid in Nov. I chose not to use them because in the past I had developed APD (Autoimmune Progesterone Dermatitis) with the progesterone bullet suppositories. So I saved them and when I found out I was pregnant I started inserting one each night that first week figuring I needed the extra dose and since my immune system was already weakened by pregnancy I wouldnt develop the rash. My progesterone levels are high enough so I stopped crinone to use the pills instead. Taking a bath tonight at almost 6 weeks I felt some pressure near the opening of my vagina and I figured it was just a ton of discharge like I've been having lately. Nope! I pushed a little and A big ole wad of what looked like chewed up wax came out! Yuck. But I feel better. I had been wondering why I was having so much more discharge than my first pregnancy and why I always felt like something was trying to come out. That second week of crinone is getting donated. No way. I'll stick with the pills. The gel bullet suppositories never did that last pregnancy. :-(

n&a2013 · January 2016

My RE recommend using the crinone first thing in the mornings. He said it helps prevent that wad of nasty stuff from all coming out at one time. If you put it in first thing it naturally works its way out little by little throughout the day as you're moving around. I still pass a little glob here or there but not the big ones.

Also to the first question......if you're having the cramping, drink more water. If you think you're drinking enough, drink a little more. I had horrible cramping when I first started the progesterone and drinking a ton of water helped them subside!

riveridgional · January 2016

I was on prometrium after all my fertility treatments except my last (switched to crinone). While on prometrium, I had very consistent period-like cramps that would sometimes radiate to my back and thighs. Then and on crinone, I've had sore boobs since a few days after beginning them. My breast soreness is pretty much gone now (10w5d) and has been for almost 2 weeks. I hadn't had sore boobs for days before my last OB appt, and I heard a strong heartbeat. That was a relief because all my symptoms had gone away and, like you, I was nervous.

That being said, if you feel the cramping is too painful/uncomfortable or too frequent, it wouldn't hurt to call the doctor to put your mind at ease. While you're on the phone, you could always mention the lack of BB soreness.

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For those on progesterone...

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