Infertility

new girl...and I just want some advice? plz thank you :)

Hi everyone,
There's probably like 15 different posts for my questions, but I'm looking to just talk with someone. No one of my friends or family know so I really just need some personal viewpoints.
I'm 28 years old. My husband and I have been together for 11 years and married for 2. This September, after a year of being in our home, paying down some debt, and getting job stability, we decided we were mentally and financially ready to start a family.
Both our families are great, but just didn't understand why we were waiting (I almost threw things at my family last holiday...one more "when is it your turn" i want to ge a grandma blah blah..question...oye..) but we wanted to not be financially strapped.
Prior to this year, I stopped taking my birth control. I was on it since I was 17.
During the last year, I had super irregular periods... like 3 for the entire year. Finally saw my dr in late spring. She ran some tests and did an ultra sound.
Tests viewed my levels as normal but the ultra sound showed signs of pcos.
My dr said it doesn't rule out pregnancy but can sometimes make it tricky. She also didn't full blown diagnose me with pcos, as the blood tests were normal, but did say I have symptoms/signs of it.
I expressed to her we wanted to start trying, so she prescribed me the following:
Provera (to enduce a period I think)
Metaformin 2pd
Clomid (durring period)
It had been 3 months since my last period, and this time around, I barely bled but had what I'd describe as "heavy spotting (brownish) for 7 days, plus cramping so I assumed this had to be my period and followed directions as prescribed and took the clomid.
2 days after my period, I thought I was ovulating (pink spotting, cm, cramping) but did the lh tests and it came back negative. My husband and I were intimate durring the day prior.
Now, friday of this week, the ov. Tests finally showed a surge friday and saturday. We were intimate those days.
We were not intimate today (ran in a 5k too tired) but did test tonight and lh test was negative.

I'm a super impatient person when it comes to life planning and I also worry.
At this point, I'm worried that what I thought was my period wasnt, and that I screwed up the process. I am also worried that if I did ovulate what my chances are of it taking effect and if my timing of us being intimate was ok or if it was off.

It seems like so many irresponsible people can get pregnant on accident but that we, who are planning things right, are going to have to go through this process in a formulaic way. Just worried snd stressed and i have no idea what to do or think.
I see my dr on Wednesday, but does anyone have any thoughts or wisdom you could share? Thank you much.

Re: new girl...and I just want some advice? plz thank you :)

  • Hi Belle! First I am sorry you are going through all of this. I have not been at this near as long as a lot of people on this board, but it doesn't sound like to me you did anything wrong, I would say any time you question-call the doc and ask...they are used to emotional, concerned and determined women with lots of questions.  Hopefully you are working with an RE and not an OBGYN.  Patience and the dreaded 2WW (2 week wait) is one of the hardest parts...and from what I read it doesn't get much better as time goes on.  Staying busy is the only advice I can give, but it is extremely hard.  I tend to get on here every night and that helps ....I wish you all the luck and patience :) 
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  • Hey there! Sorry to hear about your struggles! Our circumstances seem pretty similar. I had been on birth control since my teens, currently 26. When my husband and I decided we were ready (about 3 years into marriage) I went off BC and had super irregular cycles. I went to my primary care physician who ran blood work which showed very slightly, like hardly at all, elevated testosterone. Off to my OBGYN I went and a few ultrasounds later I was dx with PCOS. I guess I have what some people refer to as skinny PCOS. I am not overweight and do not have any insulin issues but I have the typical cystic looking ovaries and anovulation.

    My first step in treatment was clomid as well. 5 cycles there with no luck. From what I have seen on these boards many women with PCOS do not have the best response with clomid. But FX that you do!!!

    To make sure you are using the clomid properly. Day one of your cycle is always the first day of FULL FLOW period. If you are having a weird cycle and are not sure you should always consult with your dr/nurse. Your doctor should monitor your cycles with a follicle check ultrasound. If they are not monitoring your cycle this way you should ask why not/see if it is a possibility. In terms of the home ovulation kits, my OBGYN told me not to even bother with them when I was on clomid. He said they were a waste of money based on how we were monitoring the cycle and triggering with an HCG shot for ovulation. Will you be triggering for ovulation or relying on your body to ovulate on its own? This will impact whether the home ovulation tests are work the Money for you.

    I was with my OBGYN doing clomid cycles with timed intercourse for about 6 months and then started with my RE. I have had better response with letrozole and injectibles.

    Likely if you need to move onto other/more expensive medications than clomid they will want additional testing to you and your DH.
  • I have no experience with PCOS, but I just wanted to say good luck!!
    Married May 2009, TTC since November 2012 (Together since 2006 ish - had my eyes on him since 2001)
    Me: 32 (33 in May), Him: 37 (January)

    DX: Me: High Prolactin, Possible Autoimmune Disease Issues, though RE not concerned (?)  New RE has a plan!!
           Him: Minor Varicocele, low morphology, slightly low count

    History:

    Beta 5/9/2016 BFP!!
    Embryo transfer scheduled for April 28, 2016 and beta test May 9, 2016 (day after Mother's Day!)
    Transfer Meds include: Lupron Depot (4/1), Minivelle Patch (every 3rd day), Estradiol (3x daily), Amoxicillin, Progesterone in Oil, Methylprednisonlone. Lovenox and baby asprin added after transfer. 

    3/22/16 - Sono Saline ultrasound cyst to be aspirated on 4/1/16 if not cleared up by 3/29 US - It cleared on its own
    Retrieval 3/4/16 - 26 eggs retrieved, 23 mature, 20 fertilized, 14 embryos currently frozen
    Starting IVF Stims on +/- Feb 22, 2016
    HSG scheduled for 1-26-16 - All clear "beautiful uterus" (though inverted)

    Switched clinics and now prepping for IVF in February / March

    Fourth IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - December, 2015 - BFN
    Third IUI -  CD3-7 100 Clomid w/ Ovidrel Trigger - November, 2015 - BFN
    Second IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - September, 2015 - BFN
    Started Prolactin Medication October 15 - Levels quickly regulated to with in normal range
    First IUI - CD3-7 100 Clomid w/ Ovidrel Trigger - August, 2015 - BFN
    After no BFPs (ever) First RE/Urologist visit in Feb 2015
    HSG w/ OB, 2014 = all clear
    Trying to conceive since November 2012
  • Thank you all! I really appreciate it. Right now I am just working with my obgyn, but she did express if we had to move further we could seek specialists. I meet with her Nov 4th to check my progesterone levels. This will help clarify questions I have for her.
  • Please please please don't take Clomid from your OB.  You need to be monitored with bloodwork and ultrasounds during your cycles with Clomid.  Also, your husband needs an SA and you need an HSG to rule out anything there.  Clomid has a 6 ifetime max usage and you could wasting cycles if your tubes are blocked or your husbands sperm has issues. Please get to an RE stat.   
  • I don't know what SA means.
    I don't know what HSG means. 
    I don't know what an RE is. 

    Why is it bad to work with a gynecologist exactly? We did progesterone bloodwork. Working on my husband to get tested, he will be going if it didn't happen this cycle. 
  • Also, my gynecologist went to Yale school of endocrinology and was an associate professor for a short time before beginning her practice in gynecology. I trust her. I am not sure I appreciate the tone, unless you are an RE yourself (looked up what it meant). You should watch how you are replying to people. A "pleading" reaction like that could panic some people, you had me going for a moment, in all honesty...
  • She actually gave you fantastic advice.
    Married to DH 10/6/12
    TTC since 5/14
    Unexplained with (controlled) hypothyroidism and suspected ovulatory dysfunction (but, I do ovulate on my own)
    Clomid 50 mg 3/15 (unmonitored) - BFN
    Clomid 50 mg + metformin 4/15 (unmonitored) - BFN 
    First RE appt. 5/15; Natural cycle 5/15 monitored with 2 mature follicles and Pregnyl Trigger (full dose) + prometrium - BFN
    6/15 HSG - clear tubes & normal uterus; great PCT test results
    TI - 100 mg Clomid + prometrium (AM & PM) + vaginal estrace (AM & PM) 6-7/15 (monitored) --> no additional response and thinned lining - BFN
    TI - Injectables (follistim + Gonal-F, Ganirelix, & 1/2 dose Pregnyl) + prometrium (AM & PM) 9/15 --> 3-7 mature follicles (3 definites and 4+ that could have matured due to trigger) @ O -->BFN + 5 large cysts
    BC for 2 weeks due to cysts
    TI - Injectables (Gonal-F, Ganirelix & full dose Pregnyl) + prometrium (AM & PM) 10/15 --> 1 mature follicle --> BFN 
    TI - Last attempt at injectables (Gonal-F, Ganirelix & 1/2 dose Pregnyl) + crinone (AM only) + vaginal estrace (AM & PM) 11/15 --> 3-4 mature follicles --> BFP!! 11/27/15 @ 13dpo (shockingly, actually waited until then to test)

    Beta #1 @ 16dpo (11/30/15) = 1,075
    Beta #2 @ 19dpo (12/3/15) = 3,150
    One baby: Saw heartbeat @ 5w5d (114 bpm; baby measuring 2.3mm)

    "Great Things are Happening"
  • bsckgb7bsckgb7 member
    edited December 2015
    Also, my gynecologist went to Yale school of endocrinology and was an associate professor for a short time before beginning her practice in gynecology. I trust her. I am not sure I appreciate the tone, unless you are an RE yourself (looked up what it meant). You should watch how you are replying to people. A "pleading" reaction like that could panic some people, you had me going for a moment, in all honesty...

    It is pleading. You should be panicked. Do a search on this board. You are risking your future fertility. 

     ETA: look for any post with Clomid and read the response from @TheBorg7of9
  • I agree don't take clomid without being monitored. My gyno put me on it and wanted me to take it for 6 months. I was like forget him and went to fertility specialist instead. Do yourself a favor and go to one. You could really do harm to your body and you might not even know it.
  • But I am being monitored and I have had bloodtests and am having frequent appointments. So I guess I am not sure what the issue is? 
  • Can't help but giggle at the name the borg... yay treckies! hmm. Will have to discuss this with her next week. 
  • @brebelle05 it wouldn't hurt to talk to a fertility specialist just to get a second opinion. whst could it hurt. Clomid didn't work for me and now I'm on injectables. If you really want to conceive then check out a fertility doctor in the area you live in. I'm sure if you said what state your from there would be someone from the same area that could give you the information if needed
  • @brebelle05 - you don't seem to want to listen to any advice you have been given here or on TTGP. I'll copy the standard Clomid from @TheBorg7of9 so you can see your risk

    • TheBorg7of9TheBorg7of9 member2500 Comments 500 Love Its 25 Answers Second Anniversary
      Ok. Hello and welcome. I have been on clomid myself and have read many stories on this board for 6 years from women on clomid.

      First of all before you take clomid, you need to make sure you don't have any other problems that would make the clomid moot. That is because clomid has a lifetime max of 6 cycles. After that some doctors won't give more clomid because of a potential concern about cancer. Although that link has not been proven. Also, if it doesn't work after 6 cycles, it's probably not going to work. The two most important tests are a semen analysis for your husband and an hsg to make sure your tubes are open.

      For each cycle you are on clomid, you need Bloodwork and vaginal ultrasounds on cycle day 3 and then starting mid cycle about every other day until you ovulate.  Opks are not reliable when you are on clomid. The tests on cycle day 3 are to measure your hormones, check for pregnancy (clomid is not good if pregnant) and check for cysts (clomid causes cysts. Also, if you start a cycle with a cyst and take more clomid, the cyst may grow exponentially and cause you to lose an ovary. I have seen some women on this site end up in the ER because they weren't monitored.)

      The ultrasounds also check if you are overresponding or underresponding. If you overrespond (like I did) you have to decide whether to cancel the cycle or risk high order multiples and a second trimester selective abortion. If you underrespond, you doc may change meds for next time.

      The ultrasounds also check your uterine lining, because clomid might cause your uterine lining to be too thin and prevent pregnancy.

      Another side effect is that clomid may dry up your cervical mucus, thereby decreasing your chances of pregnancy. That's why reproductive endocrinologists usually pair clomid with an intrauterine insemination.

      Finally, I would very highly recommend you see a reproductive endocrinologist for infertility and not an OB. REs are the experts here, not OBs and they do the proper tests and monitoring as a matter of course.

  • bsckgb7bsckgb7 member
    edited December 2015
  • PiperellaPiperella member
    edited December 2015
    Welcome to the board. You may want to read the first few threads above for newbies. Most of the abbreviations and acronyms are spelled out there. When dealing with infertility, the most logical next step for women would be to see an RE. Some women do try a few rounds of clomid with an obgyn, but an RE is a specialist with infertility, and has many more treatments and tests they can perform to help you more than an obgyn has, no matter how fantastic he or she is.
  • edited December 2015
    Ok, I am sort of confused. I thought you were like at least 12 dpo and thinking you were pregnant bc of the symptoms. I read your post you just posted yesterday, and the story/timeline sounds different. Please help explain, I would love to offer advice but I want to make sure I understand first.

    On December 4 in Trying to Get Pregnant
    Hello, Newbie here again. 2nd posting. I have some issues need some clarity on. Have an appointment with my gyno, just going insane. lol

    Posted before, very helpful/encouraging.
    28 years old...been receiving treatment for 2 months now to try and regulate my irregular cycles most likely caused by Polysistic O syndrome. Went on provera, clomid, and metformin. Still on metformin daily. 1st Cycle in October seemed to go well. Everything worked. I had some "typical" symptoms. Thought I even may have had some implantation bleeding but turned out just a week of brown spotting before my period. Progesterone levels were good, gyno liked how everything worked, took like 4 pregnancy tests and the AF came on the day it was supposed to. Que disappointment. Time for round two.

    AF came, but this time, it was mega short....3.5 days. October it was 5 days and then a week of brownish spotting. This time, 3.5 days, no spotting, just stopped. Took clomid days 3-5 as prescribed. Kept log on my ap. Did an LH test on day 12 as prescribed, LH surge. Hubby and I were intimate 3 times, every other day. I am assuming I ovulated, had the "typical" cm, slight twingeing on my left ovary area, but it was not as "obvious" as last time, so part of me is still skeptical. Didn't pee soon after day 3, developed a Uti 5dpo. Began taking bactrim for that. Relatively "dry" 2-3 dpo 7 dpo I was super nauseous. Got sick in the am. 9 dpo, also nauseous. Had to actually leave my classroom in class to excuse myself. I continued to have nausea symptoms for 4.5 hours. Didn't get hopeful because bactrim side effects can be nausea. But I am actually throwing up which is bother some. Definitely not feeling anything else with the nausea so I know I'm not sick. 10dpo slight "pulling" feeling in my lower abdomen. Off an on, maybe 3 times that day? Curious so I took a pregnancy test, even though it was way early... Negative. 11dpo I noticed I was damp in my panties. I decided to check my cm and after examining my finger, had some white residue. 12dpo, same cm, little more of it on my finger, white. Does not have any weird odor. Felt a "pulling" again 3 times today (did it just a few moments ago). I had nausea this am, didn't throw up, went away. Went to an early dinner with hubby around 430, felt fine. Walked around, nausea again. Threw up twice. I have had the worst gas. I literally burped probably 15 times in the last 3 hours. Again, thinking it's a side effect of the UTI medication, but hubby is skeptical. Says the throwing up/gas does not seem like me. Took a bath and noticed my nipples are a bit sore, mainly my left one. But my boobs themselves don't feel sore. I have had no spotting (sign of implantation, right?) Sorry if TMI.

    I have been reading online, which my gyno told me not to do. lol I can now see why. I will say, some of the posts on other sites, people are super rude to people like me and just say, "just take a damn pregnancy test." Well, isn't a site like this to get information before taking a pregnancy test and to listen to others experience? So, if you are going to say something unkind such as that, please refrain from responding. I am not dumb, and know the obvious way to know is a pregnancy test. However, I don't want to jump the gun and be let down. Also, I have already dropped $100.00 on tests and really don't want to waste anymore money if it's going to be for nothing.

    Venting: Part of me is also just annoyed. I am annoyed that PMS symptoms are exact to pregnancy symptoms. I am annoyed that my husband and I have done everything right (together forever, married, pay some debt, home, then kid) and we can't just automatically conceive, but irresponsible people around us can get pregnant like that. I am a natural worrier, a planner, and worry that it wont happen in a timely fashion (we don't want to be old parents and want 2 kids).
    Part of me is annoyed with mom, whom I love dearly, but who would "cryptically" talk about her "difficulties" with getting pregnant with my brother and I but brushed it off as nothing. I didn't find out until last week that she has polysistic and endometriosis, both are hereditary. I would have like to have known this, I don't know, years ago, and I would have stopped my birth control a hell of alot sooner than just 1 year ago in order to allow more time for my cycles to get on track.
    I know I am supposed to be stress free, I am really trying. I am keeping busy (I teach high school so I am busy all the time anyways), I am doing yoga, reading/adult coloring book when I have free time. But I can't help but be annoyed with the sense of urgency around this subject.

    So, informed ladies of the interwebs, what are your thoughts? Should I try testing again? Wait and see? Can you have symptoms like the above without implantation bleeding and be pregnant? Is there anyone else like me that is worried about "the clock" ticking away, how are you coping?

    Thanks again. Much appreciated.

    RE DX for me: Anovulatory cycles/Mild PCOS  RE DX for DW: Endometrioma on left Ovary.
    Reciprocal Ivf Feb 2016. DW eggs and I am carrying. EDD: 10/27/16

    Pregnancy Ticker
  • But I am being monitored and I have had bloodtests and am having frequent appointments. So I guess I am not sure what the issue is? 

    By being monitored we mean you should also be receiving multiple vaginally ultrasounds throughout your cycle along with bloodwork . How does your OBGYN monitor your ovaries? (Size, quantity, etc) Also, since you have some pcos symptoms, how is she monitoring that no cysts are forming on your ovaries?

    RE DX for me: Anovulatory cycles/Mild PCOS  RE DX for DW: Endometrioma on left Ovary.
    Reciprocal Ivf Feb 2016. DW eggs and I am carrying. EDD: 10/27/16

    Pregnancy Ticker
  • Hello Everyone, I just had my first IUI, and I had 2 blood tests and 2 ultrasounds prior. I was on clomid as well. I actually took a lower dose than the doc wanted because I didn't want more hormones in my system that I needed. I think your case in tricky since you've been on meds for 2 or 3 cycles. I'm not sure if most REs only work with people who have been trying for a year or not. I would ask your OB what other diagnostic tests are available and if you can monitor how many eggs you are producing each month. I echo the other ladies that a SA for your spouse is very important. My RE would not do any treatment before the SA for hubbs or an HSG for me.
    *******
    Married Jan. 2014
    Me:36 DH: 39
    TTC since August 2014, Mild PCOS + uterine fibroids
    Myomectomy June 2015- 18 fibroids removed
    IVF #1, May 2016 = 32 eggs retrieved, 12 fertilized, 7 frozen, 3 PGS normal
    FET#2, July 2016 = one embryo transferred 
    TRIGGER
    BFP! Beta = 617
    Due date = 4/9/17
    Delivery date = 3/20/17
  • mskeenanmskeenan member
    edited December 2015
    I don't think @bsckgb7 was trying to be rude just trying to be helpful ! If we seem passionate in our responses it's bc we care. A lot of us wish we had had the advice of others before we made different decisions along this journey !

    I thought I could see the OBGYN for my issues as well as my OBGYN is a fabulous doctor with excellent credentials as well . However , after I met with an RE after having trouble I knew I had made the right choice . An REs specialty is getting people pregnant . An OB has a lot of other responsibilities . For me I guess it just helped knowing that my RE ONLY does fertility work and runs extensive tests and monitors me constantly . Ultimately if you are getting all the monitoring appointments at your OB and you feel comfortable with them then by all means that is great !!

    It can't hurt to ask about Femara as an alternative to clomid . Femara doesn't have nearly as many side effects (from what I have heard ) and doesn't thin your lining out . I know many women who have switched from clomid to femara and had much better experiences !

    Wishing you the best of luck and sending baby dust your way !!

    **BFP and loss warning**

    Me: 29
    DH: 29
    Us: Married Valentine's Day, 2015
    DH: No issues.
    Me: PCOS, unexplained infertility (whatever that means!!)
    June 2015 Medicated TI cycle: BFN
    July 2015:  Medicated TI cycle: BFN
    August 2015: IUI: BFP. Chemical pregnancy :(
    October 2015: IUI: BFN
    January 2016: Egg retrieval: 10 frozen embryos!
    March 2016: FET Cycle- 2 embryos transferred!: BFP !
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