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Positive for Downs - Cell Free DNA Blood Test (Qnatal)

sherri&davidsherri&david member
edited October 2015 in High-Risk Pregnancy
Im 44 and I had this test completed and it came back positive for Downs. Was advised this test is 99% accurate and a false positive is very unlikely. I went ahead and did a CVS to get a final result and waiting on results, but I'm devastated. Has anyone else gone through this?
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Re: Positive for Downs - Cell Free DNA Blood Test (Qnatal)

  • mac-n-cheesymac-n-cheesy member
    No experience but I am very sorry you are having to go through this.
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  • PlainJane8350PlainJane8350 member
    Me, too. Praying.
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  • sherri&davidsherri&david member
    Thank you @lynem29 and @PlainJane8350
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  • PlainJane8350PlainJane8350 member
    Lots of women on the board receive "positive" tests...it's a ratio/odds thing, isn't it? But have negative amnio. Search the boards, I've only read a handful of posts where an abnormality is confirmed. Still praying!
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  • AnonymousMomAnonymousMom member
    PlainJane8350 said:
    Lots of women on the board receive "positive" tests...it's a ratio/odds thing, isn't it? But have negative amnio. Search the boards, I've only read a handful of posts where an abnormality is confirmed. Still praying!
    In the case of the quad screen [Inhibin A, Alpha Fetoprotein, HCG, and Estriol] you are correct that these values calculate risk of certain conditions but can also be elevated or decreased for other reasons.  In contrast, the OP had free cell DNA testing so although there can be false positives (and false negatives) they are actually looking for specific concerning DNA sequences (like trisomies or chromosomal deletions) in the placental DNA and the accuracy is much better.
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  • kdebesche4kdebesche4 member
    edited November 2015
    I am sorry to hear you are going through this! A friend of mine has a 2 year old with DS and has a blog that you might find helpful to read: themaidenmetallurgist.com
    She is very upfront about the joys and challenges she faces each day and has some great information on her page.
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  • smb722smb722 member
    @sherri&david praying for you.. Any update?
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