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New plan: Parlodel (children mentioned)

amyac15amyac15 member
in Trouble TTC
We had our official sit down with RE yesterday. This is my second time with this process (9 yr old twins from clomid, dx was unknown infertility, with ex husband) and dh's first. TTC 14 months. 2 cycles of clomid resulting in bfn's. Moved cross country in August & started with a new RE last month. All labs have looked good except slightly elevated prolactin. Dh SA was great except increased viscosity. Initial exam & labs last month. Yesterday was blood draw, worst one yet. I have tiny uncooperative veins. After 6 pokes (one of which hit a nerve OUCH!) they finally had just barely enough blood. Followed by quick CM exam & follicular ultrasound. We finally sat down with dr almost 2 hrs later. SA culture showed bacteria. Apparently this bacteria is from the prostate, is common, and can be passed back and forth between us with no symptoms. 14 days of doxycyline for both of us & use protection until meds finished. That should help with the increased viscosity. Then me. Current thought is hyperprolactinemia is my issue. Dr thinks my previous T-TTC is different than current. Prescribed Parlodel until I get a BFP & repeat prolactin labs in 4 weeks. Its hard to believe that this could be the only issue and that previous issues had no correlation to current. Trying to feel hopeful but preparing for what might be next if this doesn't work. Anything I should know about Parlodel?
Sorry for the long post. Thanks for reading.
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Re: New plan: Parlodel (children mentioned)

  • Stepmomttcmy1Stepmomttcmy1 member
    I have taken Parlodel for the last 8 yrs. While I have not gotten pregnant(mfi is our issue) it did allow me to have regular cycles and ovulate each month, something I wasn't doing before. My gyn put me on the parlodel, 2.5 mg twice a day. My RE lowered the dose to 2.5mg once daily back in March and I am still ovulating and having regular cycles.
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  • amyac15amyac15 member
    @Stepmomttcmy1 I'm assuming you were put on Parlodel for increased prolactin, like myself? Did your Dr discuss what could cause the increased levels? Mine started me on 2.5mg once daily and just said it should decrease levels and hopefully be our fix but then i googled it and saw that increased prolactin can be caused by pituitary tumors? No cause was mentioned to me. Wondering if anyone knows what else could cause the increase.
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  • riveridgionalriveridgional member
    Increased prolactin can be caused by pituitary tumors, increased stress, excessive nipple stimulation, and elevated TSH levels (hypothyroidism). Mine was slightly elevated for a few months and my OB just wanted to monitor it. My TSH level was in the high normal range when my prolactin was 29. He retested my prolactin 2 months later and it was 36. He hadn't retested my TSH at that time. When I went to my RE my TSH level was on the low side of high, something like 4.18. He never told me my prolactin level. Anyway, he increased my levothyroxine (synthroid) from 75 to 112. My prolactin level at the next check was 18. My RE told me that the level, therefore, was artificially elevated by my high TSH.

    If it is caused by a tumor, those are benign in 99.9 percent of cases and usually reduce with medication. You would have to take your medication everyday for life, however, unless an MRI shows the tumor has decreased or gone away for 2 years. If you have concerns about the cause of your elevated prolactin level, ask your doctor. He should be able to give you guidance.
    Married to DH 10/6/12
    TTC since 5/14
    Unexplained with (controlled) hypothyroidism and suspected ovulatory dysfunction (but, I do ovulate on my own)
    Clomid 50 mg 3/15 (unmonitored) - BFN
    Clomid 50 mg + metformin 4/15 (unmonitored) - BFN 
    First RE appt. 5/15; Natural cycle 5/15 monitored with 2 mature follicles and Pregnyl Trigger (full dose) + prometrium - BFN
    6/15 HSG - clear tubes & normal uterus; great PCT test results
    TI - 100 mg Clomid + prometrium (AM & PM) + vaginal estrace (AM & PM) 6-7/15 (monitored) --> no additional response and thinned lining - BFN
    TI - Injectables (follistim + Gonal-F, Ganirelix, & 1/2 dose Pregnyl) + prometrium (AM & PM) 9/15 --> 3-7 mature follicles (3 definites and 4+ that could have matured due to trigger) @ O -->BFN + 5 large cysts
    BC for 2 weeks due to cysts
    TI - Injectables (Gonal-F, Ganirelix & full dose Pregnyl) + prometrium (AM & PM) 10/15 --> 1 mature follicle --> BFN 
    TI - Last attempt at injectables (Gonal-F, Ganirelix & 1/2 dose Pregnyl) + crinone (AM only) + vaginal estrace (AM & PM) 11/15 --> 3-4 mature follicles --> BFP!! 11/27/15 @ 13dpo (shockingly, actually waited until then to test)

    Beta #1 @ 16dpo (11/30/15) = 1,075
    Beta #2 @ 19dpo (12/3/15) = 3,150
    One baby: Saw heartbeat @ 5w5d (114 bpm; baby measuring 2.3mm)

    "Great Things are Happening"
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  • Stepmomttcmy1Stepmomttcmy1 member
    My Dr had me get an Mir which came back clear, no pituitary tumors. I have been on the parlodel so long and am now getting regular periods so my prolactin levels have not been tested since. My RE did say when/if I get pregnant I would stop the meds so my body would take over and I would be able to lactate.
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