Multiple follicles: Trigger shot?

sandy_and_bbh · September 2015

Hi! I had my u/s yesterday and we have three good sized follicles. Yay! I am scheduled to have my ovidrel injection today. My questions is this:

Will getting the shot further increase my chance of multiples? And would it be dumb to not get the shot and hope for the best?

I don't want multiples but don't want to waste a chance this month on conceiving.

Thoughts?

juliehollz13 · September 2015

Hi - talk to your RE because it all depends on the size of the follicles. Even if all 3 are a good size, there's no guarantee that ALL three will rupture, fertilize and implant. Sure, the risk is higher, but anytime you have a medicated cycle your chances of multiple go up. Good luck!

bsckgb7 · September 2015

Most REs are perfectly happy with 3 follicles. What's your progesterone levels? I had 4-5 mature follicles but my Progesterone was a little low, so RE suggested I continue the cycle (and did). I second PP, what does RE say?

bsckgb7 · September 2015

Also, what was the medication? Was it Follistim or Letrozole/Clomid?

Sarafuss · September 2015

Ditto PP's. I conceived on a cycle with 3 follicles and also conceived with 4 follicles (one baby each time). If your RE is checking your estrogen levels with b/w at the time of ultrasound that number will give you a better idea of how many eggs you potentially have. Not every follicle has a mature egg in it. I am also curious about the medication you are taking. I have taken Femara and the risk is lower with that versus injectible meds.

babyexpress · September 2015

Correct me if I'm wrong ladies, but isn't the trigger shot just making sure that you ovulate within 24-36 hours? If your follies were checked and they looked mature enough, than that is the time to take the trigger and get ready for the IUI or TI. I know other bumpers on here that had 4 mature follies and still got a BFN. I think your chances of multiples goes up and like @juliehollz13 said that it goes up no matter what when you have a medicated cycle. But i think the chances of multiples are around 5%.

bsckgb7 · September 2015

babyexpress - Correct, the trigger makes you ovulate. If you have too many follicles you risk multiples and may want to consider canceling the cycle (and I think that's what the OP was considering).

I don't really believe a statistic of 5% as some ladies are super conservative and would cancel before risking multiples and therefore skewing the numbers.

Also, Follistim/injectibles drastically increases the chance for multiples over oral medication. So that's why it was also asked what medication.

babyexpress · September 2015

Got it. I did Follistim this round and did not last month. I went from 1 mature follie last month to 4 this month. My RE discussed the chances of multiples going up this round and I had to sign another consent form.

I knew it going in.....Its a personal decision for sure....and a risk.

bsckgb7 · September 2015

Right/ So obviously important to OPs question (different medication respond differently). Also, my RE said follistim follicles are stronger/better and more likely to be fertilized.

Hey our Betas are the same day!!

babyexpress · September 2015

@kgbbsc7 oh cool, keep me posted. Exciting!

By the way, Dr. Google told me about the 5%, so he could be full of it.

bsckgb7 · September 2015

I believe the 5% may be correct, that continue with a cycle. I wish there would be a statistic for how many cancel a cycle for the RISK of multiples (from too many follicles). Also, my RE said twins with Follistim was about 20% chance. Some studies even go up to 30% chance of twins with injectables.

babyexpress · September 2015

I'm good with 1 baby, I'm good with twins. Whatever is planned for me i'll take....well except being an OctaMom.

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Multiple follicles: Trigger shot?

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