Pregnant after IF

AFP results. Any experience?

I got a call from OB nurse saying my afp results were normal. Great. I then asked for the number, which was 1.21. I thought normal was 10-150? If low is indicative of chromosomal issues how is that normal? I had a normal Verify test a few mos ago. Should I be worried?
Me: 37, DH: 38: ttc 7 years, dx: unknown
10/11: after 2 years, saw a RE, FSH 5.4
11/11: BFP! (surprise after thyroid & normal hsg),
12/11: missed m/c after 7 week u/s, 1/12: D&C
6/12 IUI#1-IUI #3: clomid = BFP!, C/P
IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
Baby Will born 8/18. He's perfect.

Re: AFP results. Any experience?

  • I wouldn't worry. Mine came back elevated and after 2 anatomy scans, they said everything looked normal. Still Not sure why my afp was elevated!
    ***BFP warning***
    Me (36) and  DH (34) married August 2010
    TTC since January 2010
    HSG in July 2011 found uterine polyps
    Surgery Sept 2011 to remove polyps
    Tried Clomid (monitored) Oct-Feb 2012
    Consult with RE April 2012
    Diagnosis ~ unexplained infertility
    May 2012 IUI-BFN 
    April 2014- IVF consult with RE
    May 2014- baseline~21 follicles, High FSH and estradiol
    IVF #1 Aug 2014~Lupron trigger protocol (Gonal-F, Menopur, Cetrotide)
    Stimmed for 9 days, trigger on 8/20~ 32-36 follicles seen, 16 measured on each side
    ER~ 8/22 ~ 36 follicles retrieved! 21 Mature, 17 ISCI'd
    8/27~Day 5 transfer of 2 BB blasts, 1 to freeze
    9/9~ BFP!! Beta #1- 978
    9/11~ Beta #2- 1965
    9/15~ Beta #3-7480
    1st ultrasound 9/24

     

    Image and video hosting by TinyPicimage

     

     

     

     

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  • It's 10-150 ng/mL or mcg/L for weeks 15-18 of pregnancy. I wonder if they gave you 1.21 in a different form, and it's actually 121 ng/mL?
    *****Siggy warning (PAIF)*****







    C (23)  S (28) - H (4)  M (2) 
    6 Angels (RPL: 11/09, 02/10, 03/10, 06/13, 09/14, 10/14) 
    Thyroid cancer & Hashimoto's (thyroidectomy 12/13, RAI 03/14, remission since 08/14)
    Ovulatory dysfunction, Antiphospholipid Syndrome (APS) *RULED OUT with confirmation test results as of 4/6/15!!!*
    Clomid + trigger + timed intercourse: BFN
    Femara + IUI: BFP!
    EDD 10/10/15
    2/9 - 5w2d - early cardiac activity!
    ER visit 2/13 - 5w6d - SCH
    2/23 - 7w2d - heart rate 165 bpm! SCH getting smaller
    3/6 - 8w6d - minor car wreck, SCH larger again
    3/30 - NT scan - lowest risk score possible at 1:10,000 for both Downs Syndrome and Trisomy 18
    4/6 - 13w2d - heart rate 165bpm :)
    5/5 - 17w3d - quick ultrasound looks like a GIRL!
  • The 1.21 might be a ratio like 1:21. Mine was in a similar ratio but I can't remember what it was! It was around 1:21 though.
    ***BFP warning***
    Me (36) and  DH (34) married August 2010
    TTC since January 2010
    HSG in July 2011 found uterine polyps
    Surgery Sept 2011 to remove polyps
    Tried Clomid (monitored) Oct-Feb 2012
    Consult with RE April 2012
    Diagnosis ~ unexplained infertility
    May 2012 IUI-BFN 
    April 2014- IVF consult with RE
    May 2014- baseline~21 follicles, High FSH and estradiol
    IVF #1 Aug 2014~Lupron trigger protocol (Gonal-F, Menopur, Cetrotide)
    Stimmed for 9 days, trigger on 8/20~ 32-36 follicles seen, 16 measured on each side
    ER~ 8/22 ~ 36 follicles retrieved! 21 Mature, 17 ISCI'd
    8/27~Day 5 transfer of 2 BB blasts, 1 to freeze
    9/9~ BFP!! Beta #1- 978
    9/11~ Beta #2- 1965
    9/15~ Beta #3-7480
    1st ultrasound 9/24

     

    Image and video hosting by TinyPicimage

     

     

     

     

  • The 1.21 might be a ratio like 1:21. Mine was in a similar ratio but I can't remember what it was! It was around 1:21 though.



    Thanks. I found out that is what is means a few days after this post. It has been so slow around this place that I haven't update my post. Thanks for the response!
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
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