hello ladies, hope everyone is on tract with their cycles and protocols
just wondering if anyone has been in my boat!!!
this is my fiance and i, IVF #1 cycle. we were set up to take follistim (150) and menopur (150) for 10 days. at day 10 of stim, my RE wasnt happy with the quality and quantity of follicles. so she continued me on the same meds. upon ultrasoubd on day 14, doc noticed that my estrogen was about 3000 and my uterine lining looked 'foggy", meaning my body had started to self produce the progesterone and it in turn affected my lining.
she then shocked me with a decision that we needed to make...... she said that there had been recent studies to show lower pregnancy success rate with such high estrogen and the foggy uterine lining. she she asked if maybe we wanted to freeze the eggs that are retrived and transfer them in 8 long weeks!!!!!
we did the ER today and got 10 eggs, we now have 3 days to decide if we want to go ahead with a fresh cycle or just hold off for a better opportunity with a frozen cycle. of course im an emotional mess about the idea of having to wait another 8 weeks........
i cant find any literature about this circumstance. has this happened to anyone else or have any of you ladies heard of this?
me:33 Fiance: 34 Diagnosis: DOR TTC since June 2013 IUI #1---BFN IUI #2--- BFN IVF #1--- BFP on 4/5/2015
ok somewhere i clicked on a wrong button and didnt mean to post this discussion on this board category. whoops...... but maybe someones success story came from the same situation as me.
me:33 Fiance: 34 Diagnosis: DOR TTC since June 2013 IUI #1---BFN IUI #2--- BFN IVF #1--- BFP on 4/5/2015
My first IVF was rough...long stims, slow growth, and a very high estrogen level. We chose to cancel because I was in so much pain and not yet ready for ER. Had we been able to push through to ER we absolutely would have frozen anything we were able to. There are some clinics that are moving to FET only cycles.
It's not an easy decision to make, but I think the smart decision is to freeze and transfer when your body calms down. If you transfer now and get pregnant, you risk OHSS, possible hospital admission for paracentisis, and other complications. If you transfer now and don't get pregnant, are you going to regret 'wasting' embyos on a less than ideal transfer?
TTC# 1 since 5/10 Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect DX: Unexplained IF Many IUI's with various meds all BFFN IVF #1 11/11 canceled due to OHSS IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum IVF #3 July 2012 ET of 3 on day 3 7/24 BFP! Healthy baby girl born at 36w4d on 3/9/13
TTC #2
IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
Beta 6/18 BFFN
FET of 2 blasts 7/24...BFP!
Healthy baby girl born at 36w3d on 3/17/15
TTC#3 IVF #5 June 2018- PGS planned, no surviving embryos IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy IVF #7 August 2019-....?
My clinic is one that moved to freeze all cycles and FETs rather than fresh. Not only do the things you mentioned effect pregnancy rates, but progesterone levels do as well. With my son, we had 6 embryos, only one turned into a blast and the four we did not transfer arrested between day 5 and 6. This time, my RE agreed to a fresh cycle only if my progesterone was low enough. It was not so we had to do a FET. We were worried none of our fertilized eggs would make it to blast, but four did. It was also a lot better for my body to return to normal state, giving the embryo we transferred a better chance of implanting.
Good luck with you decision, this whole process is not easy.
TTC #1 since 3/2011
DX: anovulatory and severe MFI
DH is a testicular cancer survivor
IVF#1 w/ICSI lupron, gonal f, ovidrel
ER 6/15/12 6R 6M 6F! ET 6/20/12
Beta #1: 154 Beta #2: 509 Beta #3: 7326
Baby Boy born 3/1/2013
TTC#2: 6/2014 all testing came back normal
IVF#2 (#1 for LO#2) 9/2014 - 17R 10M 10F 4 blasts frozen on day 6.
Sorry you find yourself in this spot. However, I'm with the other ladies in doing a freeze all. Unless your uterus is in optimal condition, you are at a very high chance for "wasting" your best embryo/embryos. Doing at FET ensures your estrogen and ute lining are 100% optimal for transfer.
My only alternate to the initial advice is if your embryos risk not making it to a 5 day blast. In my situation we did a 3dt of 2 embryos because we had a low fertilization rate and only had 5 of 11 growing, of which 3 looked decent.
Ask about your clinic's freezing guides. Maybe if you get to day 5 and several look good to freeze and you have one or two that won't be good enough to freeze, they can put those back since they would otherwise be discarded.
Good luck! IVF is super stressful anyway. When things doing go according to plan it seems 1000x worse.
TTC Since 3/2010 Me-36, Unexplained Infertility, DH-35, all clear Clomid 50mg 12/2011 = BFN Clomid 100mg 1/2012 = BFN, with Cyst IVF #1 Lupron/Menopur/Gonal-f/HCG Trigger ER 4/19/12 = 11 retrieved, 6 fertilized, ET 4/22/12 = 2 transfered (day 3), remaining 3 weren't good enough to freeze Beta 5/3 = BFP, 87 Beta #2 5/7 560.9 Beta #3 5/9 1376.5 First u/s One Baby, 125bpm! Second u/s, 176bmp! Kicked over to the OB by the RE at 8w. Team Green!!
Baby girl J arrived two weeks early! Born into water, med-free. Hooray for Team Pink!
TTC #2 - back to the RE, treatment started 12/2014.
I agree with everyone else. I know that 8 weeks seems like such a long time when you are in the thick of an IVFS cycle, but I the grand scheme of things 8 weeks is not that long. It is definitely worth it to wait 8 weeks to transfer if it will increase your chances of having a successful cycle.good luck!
Unexplained Infertility
After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!
TTC #2 After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!
hey ladies thanks for your responses and advice. i think we are leaning towards freezing also.... all the research that we've done suggests that freezing is the better way to go although the wait is going to be really hard for me. the endocranologist called this mornign and said that 9 of the 10 follicles, fertilized. we will get another update on tuesdsay.
me:33 Fiance: 34 Diagnosis: DOR TTC since June 2013 IUI #1---BFN IUI #2--- BFN IVF #1--- BFP on 4/5/2015
Re: IVF #1, long stim cycle, high estrogen...... now have a rough decision to make.....
Diagnosis: DOR
TTC since June 2013
IUI #1---BFN
IUI #2--- BFN
IVF #1--- BFP on 4/5/2015
It's not an easy decision to make, but I think the smart decision is to freeze and transfer when your body calms down. If you transfer now and get pregnant, you risk OHSS, possible hospital admission for paracentisis, and other complications. If you transfer now and don't get pregnant, are you going to regret 'wasting' embyos on a less than ideal transfer?
Good luck! I know its not easy!
Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
DX: Unexplained IF
Many IUI's with various meds all BFFN
IVF #1 11/11 canceled due to OHSS
IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
Healthy baby girl born at 36w4d on 3/9/13
TTC#3
IVF #5 June 2018- PGS planned, no surviving embryos
IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
IVF #7 August 2019-....?
TTC #1 since 3/2011
DX: anovulatory and severe MFI
DH is a testicular cancer survivor
IVF#1 w/ICSI lupron, gonal f, ovidrel
ER 6/15/12 6R 6M 6F! ET 6/20/12
Beta #1: 154 Beta #2: 509 Beta #3: 7326
Baby Boy born 3/1/2013
TTC#2: 6/2014 all testing came back normal
IVF#2 (#1 for LO#2) 9/2014 - 17R 10M 10F 4 blasts frozen on day 6.
FET #1 10/15/14 - Beta #1: 216 Beta #2: 823
Baby Boy born 7/10/2015
Me-36, Unexplained Infertility, DH-35, all clear
Clomid 50mg 12/2011 = BFN
Clomid 100mg 1/2012 = BFN, with Cyst
IVF #1 Lupron/Menopur/Gonal-f/HCG Trigger
ER 4/19/12 = 11 retrieved, 6 fertilized,
ET 4/22/12 = 2 transfered (day 3), remaining 3 weren't good enough to freeze
Beta 5/3 = BFP, 87 Beta #2 5/7 560.9 Beta #3 5/9 1376.5 First u/s One Baby, 125bpm!
Second u/s, 176bmp! Kicked over to the OB by the RE at 8w. Team Green!!
I would freeze all since then your body can recover and be in an ideal state for transfer.
Best of luck with your decision
Unexplained Infertility
After two Clomid cycles, three injectable IUI cycles, two IVFs, two miscarriages, and one lap surgery, IVF #2 has brought us our little boy!
TTC #2
After months of being postponed or cancelled, FET #1.3 (Natural FET) brought us twin girls!
Diagnosis: DOR
TTC since June 2013
IUI #1---BFN
IUI #2--- BFN
IVF #1--- BFP on 4/5/2015