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Headache and stomach issues on Letrazole?

mrspotatohead91mrspotatohead91 member
in Trouble TTC
Just wondering if anyone has had problems with a bad headache and stomach issues on letrazole. I don't remember this from the last cycle so maybe I have a virus. Just wanted to see if it could be related. Thanks!
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Re: Headache and stomach issues on Letrazole?

  • Karenb676Karenb676 member
    I am just curious what letrezole is. I see many of you taking that. I am doing iui as well and I don't take that. I am just curious to learn what else is our there. Is that a shot to help grow follicles? How often do you take it? I take bravelle but only on day 9 and again if needed before the iui. The only side effect i had is crying for a day. But that only happened the first cycle.
    image

    Smile, Be Happy, and Live Life to the fullest!!!!

    *************************  Siggy Warning (Loss mentioned)************************************
    Me:  38  PCOS
    DH: 37 Everything normal 
    Sept. 2013   Married and started TTC
    March 2014   CP
    Aug 2014     CP 
       HSG and MRI done
    Sept. 2014   Started seeing RE
    Dec. 2014  First IUI
    Clomid, 75 mg bravelle on Days 9 and 11, Ovidrel- Trigger
    Jan. 2015  2nd IUI  
    Clomid, 150 mg bravelle on Days 9 and 10, Ovidrel-Trigger
    Feb. 2015  3rd IUI
      

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  • mrspotatohead91mrspotatohead91 member
    I started with 2.5 mg last cycle and needed a boost of 5 mg because my follicles were slow to grow and don't remember the side effects. Makes sense that they get worse each cycle. Now I'm on 5 mg and have had a headache the whole time! Two more nights left of taking it this cycle. Glad to know this is a fairly common symptom but I will definitely be talking to my RE about it because the headache is so intense! @Karenb676‌ I take letrazole on cycle day 3-7. It is similar to clomid. Followed by a trigger shot once the follicles are mature.
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  • Karenb676Karenb676 member
    Thank you @mrspotatohead91 for explaining that for me.  I didn't realize there was another drug out there like clomid.  Now I can get a better feel for what people are talking about here.
    image

    Smile, Be Happy, and Live Life to the fullest!!!!

    *************************  Siggy Warning (Loss mentioned)************************************
    Me:  38  PCOS
    DH: 37 Everything normal 
    Sept. 2013   Married and started TTC
    March 2014   CP
    Aug 2014     CP 
       HSG and MRI done
    Sept. 2014   Started seeing RE
    Dec. 2014  First IUI
    Clomid, 75 mg bravelle on Days 9 and 11, Ovidrel- Trigger
    Jan. 2015  2nd IUI  
    Clomid, 150 mg bravelle on Days 9 and 10, Ovidrel-Trigger
    Feb. 2015  3rd IUI
      

    Report Reply
  • SND1231SND1231 member
    I have taken only Letrozole never Clomid but have had horrid headaches, trouble sleeping, and quite a bit of stomach issues. It's all normal!
    Married: 12/15/2012    TTC: 08/2014
    Husband: 26 SA: normal
    Me: 23 Low AMH and damaged ovaries due to chemotherapy.
    No AF or O in 3 years. HSG showed a slight T shaped uterus.

    High Risk OB 9/29- got the ok to get pregnant.
    RE Appt:  10/28/ U/S showed follicles, but also small damaged ovaries.
    B/W results CD0: all normal except low AMH at 1.3
    Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
    Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
    Cycle 3-January (TI)- Femera 5 mg, 2mg Estra    doil, and Trigger=


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  • pinkdoggiepinkdoggie member
    I did have a little trouble sleeping with femera but I would take that any day over the side effects I got from Clomid. What you're going through sounds normal! :)
    Me: 25 Dh: 25 Married since July, 2011
    Diagnosed with PCOS 2010
    TTC since December, 2011 (SA is Normal)
    2012-tried natural w/Metformin 1500 mg
    11/12 -Saw an OB, bloodwork revealed everything normal except for highish blood sugar levels
    1/13: Clomid 50 mg - No response
    2/13: Clomid 100 mg O'd BFN
    3/13: Clomid 100 MG O'd BFN
    4/13-6/13: Clomid 150/200 mg O'd BFN 
    Stopped treatment because of money issues and began to try naturally again from June-October 2013
    Benched until November 2014 - Started seeing RE, discovered that lining was very thin
    November 2014: Started Femera 5 mg -No response BFN >:(
    December 2014: Upping Femera, injectables are the next step if I respond 
    Also: Changed RE, first appointment on Friday, so treatment is subject to change this month


    3T December Siggy Challenge - Favorite Holiday movie scene
    The Christmas Story

    image

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  • MustangChicMustangChic member
    I've taken 2 rounds of letrozole and had different side effects with each round. First round was 2.5mg. I had a headache and horrible bone aches. The only way I could describe it was like growing pains. I was very uncomfortable no matter what I did. The second round was 5mg and my only real side effect was the headaches. Both times the side effects started about a day or 2 in and lasted about 2 days after I was done taking it. I hope you are feeling better soon!
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  • tiffmich08tiffmich08 member

    I think everyone else has already commented, but just one more from a "letrozole taker." I did have headaches too and trouble sleeping. Also, not sure if this is from the meds, but my right thigh would get numb at night, only while sleeping. This has happened SEVERAL times, it is so weird! Never noticed this until I started taking Letrozole.

     

    @karenb676 Letrozole is also known as Femera. It's actually a drug they use for breast cancer, from the research I've done, but for infertility purposes, it helps to grow more mature follies.

    Me: 34 (all tests normal) DH: 35 (all tests normal)
    Married 2013 
    TTC since October 2013 
    First RE visit after TTC naturally-Oct 2014
    HSG test Oct 2014-no blockage
    Non medicated IUI #1-Nov 2014-BFN
    Letrozole 5MG and Trigger Shot IUI #2-Dec 2014-BFN
    No Change in Meds-IUI #3-Jan 2014-Currently in TWW
     
     
     
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  • blsav23blsav23 member
    edited January 2015
    Karenb676 said:

    Thank you @mrspotatohead91 for explaining that for me.  I didn't realize there was another drug out there like clomid.  Now I can get a better feel for what people are talking about here.

    Letrozole is a "newer" med for infertility. It is supposed to have less SE than clomid, specifically it doesn't thin your lining as much. I have also read that it produces better quality eggs than Clomid.
    DH & I married 12/17/2012
    Me (31)-dx w/PCOS 2007, when married to ex-husband after MC
    DH (41)-no MFI
    07/2014-Femara 5mg + trigger + IUI= chem preg ;(
    08/2014-Femara 5mg + trigger + IUI + 2nd trigger= BFN
    09/2014-Clomid 100mg + trigger + IUI + 2nd trigger= BFN
    10/2014-benched due to RE out of town, tying naturally!
    11/2014-benched due to cyst
    12/2014-Femara 5mg + stair step with additional 5 days Femara 5mg + trigger + IUI=BFN
    01/2015-Femara 5mg + Gonal F 25 units + trigger (plus additional Gonal F 100 units on trigger night) + IUI= BFP!!! Twins due 10/2015
    09/28/2015- Surprise!  Conrad and Hudson born at 35w6d!  
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