Success after IF

PGD and PGS testing and normal embryo transferred (FET) ended in mc at 7 weeks

Hi ladies, I post on the secondary infertility board and I have had 2 cp's 1 D&C and 1 FET that ended in mc at 7 weeks.....I have a 3 year old daughter that I had no issued except LPD and that still resulted in a natural pregnancy after just 3 months of trying.

We are under the care of an RE and I am 37 and hubby 38.   We have had RPL testing and semen analysis and all normal, yet I find myself with loss #4.....I am so discouraged and am looking for some success stories of anyone in any similar situation.  My miscarriage happened after heartbeat of 132 at 7 weeks.  I thought that PGS and PGD testing was instrumental in avoiding miscarriages with chromosonal abnormalities.   We are still waiting for results because it happened right after Christmas.  

My beta last week was still 40 so am going back tomorrow morning for another blood test....I have to wait for AF and then hopefully will do another FET in March..I still have 9 "normal embryos" on ice......but my confidence is waivering.   Thank you so much for listening and possibly sharing...Thanks again

Re: PGD and PGS testing and normal embryo transferred (FET) ended in mc at 7 weeks

  • I'm so sorry for loss :(

    Unfortunately, even normal embryos can result in unexpected m/c; there is no guarantee.

    Have you had an immunity work up? Some RE's are not immune friendly (meaning they don't believe in immune problems causing losses).

    There are a few ladies around who have battled immune issues successfully and they can give you more information on that.
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    TTC# 1 since 5/10
    Me:34 Type 1 Diabetes, Ankylosing Spondylitis, Hypothyroid DH:35 Perfect
    DX: Unexplained IF
    Many IUI's with various meds all BFFN
    IVF #1 11/11 canceled due to OHSS
    IVF #2 Feb/March 2012 ET of 2 on day 3 4/7 BFP! 5/1 u/s blighted ovum
    IVF #3 July 2012 ET of 3 on day 3 7/24 BFP!
    Healthy baby girl born at 36w4d on 3/9/13

    Baby Birthday Ticker Ticker
    TTC #2
    IVF #4 May/June 2014 ER 6/4 18R 8M 8F ET 6/9 1 blast, 2 frosties
    Beta 6/18 BFFN

    FET of 2 blasts 7/24...BFP!
    Healthy baby girl born at 36w3d on 3/17/15

    TTC#3
    IVF #5 June 2018- PGS planned, no surviving embryos
    IVF #6 August 2018- ET of 2 on day 3 - Chemical pregnancy
    IVF #7 August 2019-....?
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  • 6 miscarriages with perfect cgh embryos

    2 miracles due to immune treatment.
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story



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    Lilypie - (ugiy)


  • I am sorry for your loss.
    After 1.5 years TTC, IUI #2= BFP 12/2/12

    Daisypath Anniversary tickers

    Baby Birthday Ticker Ticker

    "And the dream that you dare to dream really do come true"


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  • I'm so sorry for your loss. I haven't posted here in forever but I just want you to know the same thing happened to me and it was so tough because I guess I figured with the testing we were pretty "safe" so it was a bigger blow because I just wasn't very prepared for it. We never really knew way.
    As encouragement I'll tell you that the other transfer we did from the same screening batch (and really our very last shot) resulted in my DD.
    Best of luck
  • I'm so sorry for your losses.

    I would agree with kmc and luvboston, and suggest immune testing.

    GL.
    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
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  • After my miscarriages I was told that despite the tests coming back (after the miscarriages) that the babies were all "normal" that there is no way for them to test for every possible micro-deletion which could result in a baby stopping developing. 

    One doctor told me to use a super high dose of progesterone, another put me on dexamethasone and my OB suggested immune testing which I had done and in my subsequent pregnancy I was treated for high levels of natural killer cells.  Many REs and docs don't really buy into immune issues causing miscarriages so if that is route you want to pursue, you need to find a specialist.

    I hope you get something figured out.

    Kelly, Mom to Christopher Shannon 9.27.06, Catherine Quinn 2.24.09, Trey Barton lost on 12.28.09, Therese Barton lost on 6.10.10, Joseph Sullivan 7.23.11, and our latest, Victoria Maren 11.15.12

    Secondary infertility success with IVF, then two losses, one at 14 weeks and one at 10 weeks, then success with IUI and then just pure, crazy luck.  Expecting our fifth in May as the result of a FET.

    This Cluttered Life

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