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Trouble TTC
ashbosity
member
Super frustrating first medicated cycle (MC mentioned)
ashbosity
member
Quick background: Me-35, husband-31, TTC since 12/12, MMC 9/13 (10 weeks), suspected ectopic 9/14 (7 weeks). I was given a preliminary diagnosis of PCOS by my OB. We finally went to a RE in November and had all the tests done and everything came back great for both of us with the exception of low vitamin D which I started supplements for immediately. We were told we should try 3 medicated cycles and if that didn't work, the next best step would be IVF (which I don't think I'm ready for). I took 5mg of letrozole CD3-7 and then had a my CD12 ultrasound. I had 7 follicles that were all about .9 to 1.1. At this point, I figured I'd be scheduled for another follicle check in a few days or put on more letrozole, but I was told just to trigger with 250mcg of Ovidrel on CD16. My cycles are usually about 32 days, so this made timing very close to my normal cycle. I had few side effects (waaaay better than the cycle of Clomid I did) other than vaginal dryness/sensitivity that made BD no fun, but we got the job done as prescribed. I had my progesterone check Monday, 9DPT and it came back at 5.8. 
I was not given the option to do progesterone supplementation (maybe it's so low it wouldn't have helped?). The nurse basically made it seem like this cycle was a complete write off. I'm guessing that level is too low to support a pregnancy?? They are planning on upping my letrozole to 7.5mg and having me use pregnyl instead of Ovidrel next cycle. The thing is that I had my progesterone monitored after my MMC. My natural cycle level was 17.9 and with Clomid it was 24.5, so this is a new thing. I had already told the RE that I was having a lot of breakthrough bleeding in the last 6-8 months, starting as early as 7 DPO which from what I can figure is related to low progesterone. I really think this may be a big part of my problem. I'm not sure if I should ask for progesterone for next cycle right off the bat or just see how things go. I really hate wasting time and money if things aren't going to work. I'm just so frustrated and so ready to have a baby that I actually get to hold. I'm trying so hard not to wallow in self pity, but it's really hard! If you're still reading, thank you. I'm looking for any advice or words of wisdom.
I was not given the option to do progesterone supplementation (maybe it's so low it wouldn't have helped?). The nurse basically made it seem like this cycle was a complete write off. I'm guessing that level is too low to support a pregnancy?? They are planning on upping my letrozole to 7.5mg and having me use pregnyl instead of Ovidrel next cycle. The thing is that I had my progesterone monitored after my MMC. My natural cycle level was 17.9 and with Clomid it was 24.5, so this is a new thing. I had already told the RE that I was having a lot of breakthrough bleeding in the last 6-8 months, starting as early as 7 DPO which from what I can figure is related to low progesterone. I really think this may be a big part of my problem. I'm not sure if I should ask for progesterone for next cycle right off the bat or just see how things go. I really hate wasting time and money if things aren't going to work. I'm just so frustrated and so ready to have a baby that I actually get to hold. I'm trying so hard not to wallow in self pity, but it's really hard! If you're still reading, thank you. I'm looking for any advice or words of wisdom.EDIT: I apologize, I thought I had done an intro post, but I guess I never officially did. My basic info is at the top of this post and I've been lurking/sporadically posting for over a year since I moved from the MC/Loss board. I appreciate all the answers and support I've already received!
This discussion has been closed.
Re: Super frustrating first medicated cycle (MC mentioned)
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=