TTC after 35

IUI cycle #2 (BFP and loss mentioned)

Well it is day 3 of my first cycle post BFP with subsequent early loss. I had labs drawn and my baseline u/s today. I showed 6 follicles on the left and 5 on the right. When my NP was going over the directions for this cycle (letrozole, gonal-f and pregnyl trigger) I asked her to convey to my RE that I would like to be as aggressive as possible. With my last cycle I took 2.5 letrozole and 37.5 gonal-f, I had 2 mature follicles. She has just called and said that my RE has given the go ahead to increase the gonal-f to 50mg! My RE will only perform IUI with 1-3 mature follicles so even if we have to aspirate to go into the IUI with 3, I'll take that chance to increase our odds. Has anyone else been where I am?
**Losses Mentioned**
Me 41, DH 38 
TTC #1 since 9/2014 AMH 3.68, FSH 6.6
IUI#1 12-02-2015 Letrozol, Gonal-F, Pregnyl, Acupuncture, BFP 12-17-2015 beta 1=72, beta 2=64, beta 3=10 MC 12-20-14 
IUI#2 01-08-2015 Letrozol, Gonal-F, Pregnyl, Acupuncture, BFP 01-23-2015 beta 1=151, beta 2=450, beta 3=6524, beta 4= 29380 u/s at 7w5d baby with heartbeat measuring 6w2d. u/s 2-24 gestational sac only, beta 59400 MC 2-24-15 @ 8w6d D&C 2-27-15. Pathology results 47XX +20

Diagnosis AMA and compound heterozygous MTHFR

Re: IUI cycle #2 (BFP and loss mentioned)

  • I haven't been in your situation. I just wanted to say I'm sorry for your loss, and best wishes for  success moving forward!
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    Elizabeth 5yrs old Jane 3yrs old
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  • Sorry about your loss, good luck this cycle. Sorry I don't have any advise for you
  • I'm just now starting my first IUI cycle so I don't have any advice. But I wanted to wish you good luck and I'm very sorry for your loss
    ****Loss Mentioned***
    Me: 41 Him: 41
    TTC since December 2013
    HSG 9/18/14 = Tubes open but T shaped uterus
    IUI #1... 1/6/2015 + 50mg Clomid = BFN
    IUI #2... 1/29 & 30/2015 + 50mg Clomid +Tigger +Progesterone = BFN
    3/14 BFFP! Natural w/acupuncture & herbs only
    EDD = 11/22/15;  No heartbeat = 7/21/15
    Cooper Midnight Johnson born sleeping 7/25/2015



    Lilypie Angel and Memorial tickers
  • Good luck to you and so sorry for your loss!
  • Praying this is your cycle!!  Not really the same situation but I have DOR and I was on fish oil, vitamin D, a good prenatal and aspirin prior to my third iui (first iui with a new RE).  I was on 150 iu of follistim for three days then they lowered my dose to 75 iu for the last six days.  I had three mature follies by the time I triggered.  I got my BFP two weeks ago!  Praying this baby stick.  It would be the first for my husband and the first for us.  I have a son who is 13.

    Secondary Infertility 38 years old (husband has no children)
    TTC since we got married 6/18/11
    Diagnosed with DOR - AMH 0.8

    Miscarriage April 2000
    Had my son 2/27/01

    IUI #1 May 2012 - BFN
    IUI #2 June 2012 - BFN

    Changed RE's September 2014
    IUI #3 December
    2014 - BFP-My Lil Blessing!!!


    BabyFruit Ticker

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