Oh no @ronniesgirl1982 that's unsettling. My AMH level is 1.7 so it's on the low side. I have had 2 cycles, last one my E2 was very low. Oh I hope I don't have another bad cycle. [-O<
@CML11 Where are you being treated? My AMH is much lower than yours (most recent was .6something). Both of my second opinion REs said they thought MDLF was the wrong protocol. I'm leaning toward an EPP protcol for my next cycle. However, there are plenty of MDLF success stories out there.
IVF #1, Stimmed for 12 days, ER 8/22/14, 9 retrieved, 7M, 7F!! Freeze all due to fluid in uterus.
FET end of October 2014 cancelled due to fluid in uterus due to possible c-scar defect
Surgery scheduled 12/12/14 to fix possible isthmocele
3/26/15 transferred one 8 cell grade 4 embryo and one 6 cell grade 3 embryo = slow rising betas for 2+ weeks = ectopic MTX shot 4/29/15
Repeat c-scar surgery June 2015
2nd and last IVF cycle August 2015, stimmed for 12 days, 2 egg retrieved, both mature and both fertilized. Transferred both 8-cell embryos on Day 3, beta 9/5/15 = BFFN
This was my protocol in October that resulted in a BFP.
I will tell you I was very skeptical at first, because I've always done antagonist protocols - 1 cancelled for dominant follicle, 1 cancelled for low response, and third time resulted in retrieval of 13 eggs (8 fertilized). My RE wanted to try microdose protocol to see if I'd get better quality. I didn't respond well at first, and he upped my dosage of menopur to the max. Only 3 fertilized and grew, and we transferred all 3 on day 3. The entire cycle I was positive it wouldn't work. I'm still a bit in shock that it did.
TTC since 11/09
me: 39 DH: 36 dx: unexplained (ugh)
January 2011 - December 2012: 4 cycles w/Clomid; 9 IUIs w/Follistim & Menopur; two IVF cycles converted to IUI (poor response/dominant follicle)
This protocol worked for me. I did 3 cycles on MDL to bank embryos. I ended up with 9 blasts 6 of which were genetically normal. My first transfer will be in dec. Good luck!!
TTC#1 since April 2011 IVF#1 July 2012 5R, 3 made it to blast, sET c/p FET#1 Aug 2012 2 blasts transferred BFN IVF#2 Oct 2012 16R/6M/6F/2-8 cell grade 1 transfer Beta 1-237.9, Beta 2-566, Beta 3-8657 US 6w3d shows one baby w/ HB 115 US 7w1d no more heartbeat/ D&C 11/30/12 normal karyotype IVF#3 Mar 2013 6R/4M/4F 1 compacting and 2-8 cell transfer ectopic pg MTX given 3 month break from TTC
IVF#4 Sept 2013--BFN IVF#5-7 Apr 2014, Jun 2014 and Aug 2014 banking embryos for CCS testing. Praying for normals!
I had a poor response to this protocol, too, though my best fertilization rate: only three retrieved, but two out of the three fertilized normally. We transferred two, but I still had a BFN, so we moved back to the antagonist and added in EPP and implantation protocols.
IVF #4 No suppression/Antagonist Nov 2014/Converted to IUI #1 = BFN IVF #4.1 Feb 2015 = cancelled IVF #4.2 April 2015 - Lupron Stop Protocol with ICSI = PGD testing of embryo indicated it was abnormal IVF #5 June 2015 EPP with Antagonist
I am DOR (AMH 0.2). I had five eggs retrieved for my first IVF cycle with MDLP back in April, four were mature, three transferred and one frozen. BFN.
We are doing another MDLP right now. RE wanted to do estrogen priming protocol (EPP) but that takes two cycles in total and the clinic is closed in December so we had to wait until January for that one and I wanted to move forward. We decided to give MDLP another shot.
There are success stories with both protocols. Based on my extensive reading, it is likely that some people produce more eggs with EPP compared to MDLP but often MDLP produces better quality eggs than EPP. But everybody is different. If this one fails, we'll try an EPP protocol
---- Siggy warning ------
Me 34 y/o DH 35 y/o
IVF#1 (ICSI)-- April 2014-- MDL with BCP, 5R, 4 ICSID, 3dt with three embryos, 1 six-day freeze (2BA grade)-- BFN
IVF#2.1 (ICSI)-- August 2014: MDL without BCP-- cancelled
Natural IUI on 11/8 -- BFN
IVF#2.2 (ICSI)--Nov/Dec 2014: MDL without BCP, 5R, 1 ICSID, frozen on day 6 (grade 2BB)
FET #1: transferred two 5 (or 6?)day embryos on January 27. Beta #1 (2/4): 158, Beta #2 (2/6): 391 Beta #3(2/9): 1187 BFP!
First u/s at 5w1d showed one gestational sac and yolk sac. Second u/s at 6w showed heartbeat at 102. Third u/s at 7w heart rate 145. EDD 10/15/2015
EPP= Estrogen Priming Protocol. You use an estrogen patch, like Vivelle, starting 10 days after your LH surge and do three days of the Ganirelix/Centrotide injections starting on the second day. Then have your period, and then start your stimming. As my RE explained it, it helps suppress you, so you can have more even growth of your follicles without over suppressing like BCPs can. I was supposed to do EPP for this cycle, but had my LH surge late and AF came before I could start the patches, so we went straight into stimming and I ended up with a dominant follicle.
IVF #4 No suppression/Antagonist Nov 2014/Converted to IUI #1 = BFN IVF #4.1 Feb 2015 = cancelled IVF #4.2 April 2015 - Lupron Stop Protocol with ICSI = PGD testing of embryo indicated it was abnormal IVF #5 June 2015 EPP with Antagonist
@ronniesgirl1981 being treated in NH satellite office and MA for the ER/ET. I read I should be at 2.25 for my age, but I guess from further research I'm in actually within range.
Re: Microflare protocol
TTC since 08/2012
DX: DOR
TTC since 08/2012
DX: DOR
TTC #3 since June 2013
BFP #1 7/21/2013--EDD 3/30/14--D&C 9/24/13
BFP #2 1/28/14--MC 2/7/14
IUI #1 5mg Femara + trigger = BFN
IUI #2 5mg Femara + trigger = BFN
IUI #3 5mg Femara + trigger = BFN
me: 39 DH: 36 dx: unexplained (ugh)
TTC#1 since April 2011
IVF#1 July 2012 5R, 3 made it to blast, sET c/p
FET#1 Aug 2012 2 blasts transferred BFN
IVF#2 Oct 2012
16R/6M/6F/2-8 cell grade 1 transfer
Beta 1-237.9, Beta 2-566, Beta 3-8657
US 6w3d shows one baby w/ HB 115
US 7w1d no more heartbeat/ D&C 11/30/12 normal karyotype
IVF#3 Mar 2013
6R/4M/4F 1 compacting and 2-8 cell transfer
ectopic pg MTX given 3 month break from TTC
IVF#4 Sept 2013--BFN
http://i61.tinypic.com/34zll06IVF#5-7 Apr 2014, Jun 2014 and Aug 2014 banking embryos for CCS testing. Praying for normals!
***************************Loss Mentioned***************************
Me 37 y/o, DH 45 y/o; DH vasectomy reversal (his 2nd marriage) 11/8/12; TTC since 12/8/12. IVF due to MFI. DOR diagnosis April 2015.
IVF #1 BCPs/Antagonist w/ICSI Jan 2014 = BFN
IVF #2 MDL w/PICSI March 2014 = BFN
IVF #3 EPP/Antagonist w/PICSI May/June 2014 = BFP!; MMC 6w4d
IVF #4 No suppression/Antagonist Nov 2014/Converted to IUI #1 = BFNIVF #4.1 Feb 2015 = cancelled
IVF #4.2 April 2015 - Lupron Stop Protocol with ICSI = PGD testing of embryo indicated it was abnormal
IVF #5 June 2015 EPP with Antagonist
---- Siggy warning ------
Me 34 y/o DH 35 y/o
IVF#1 (ICSI)-- April 2014-- MDL with BCP, 5R, 4 ICSID, 3dt with three embryos, 1 six-day freeze (2BA grade)-- BFN
IVF#2.1 (ICSI)-- August 2014: MDL without BCP-- cancelled
Natural IUI on 11/8 -- BFN
IVF#2.2 (ICSI)--Nov/Dec 2014: MDL without BCP, 5R, 1 ICSID, frozen on day 6 (grade 2BB)
FET #1: transferred two 5 (or 6?)day embryos on January 27. Beta #1 (2/4): 158, Beta #2 (2/6): 391 Beta #3(2/9): 1187 BFP!
First u/s at 5w1d showed one gestational sac and yolk sac. Second u/s at 6w showed heartbeat at 102. Third u/s at 7w heart rate 145. EDD 10/15/2015
***************************Loss Mentioned***************************
Me 37 y/o, DH 45 y/o; DH vasectomy reversal (his 2nd marriage) 11/8/12; TTC since 12/8/12. IVF due to MFI. DOR diagnosis April 2015.
IVF #1 BCPs/Antagonist w/ICSI Jan 2014 = BFN
IVF #2 MDL w/PICSI March 2014 = BFN
IVF #3 EPP/Antagonist w/PICSI May/June 2014 = BFP!; MMC 6w4d
IVF #4 No suppression/Antagonist Nov 2014/Converted to IUI #1 = BFNIVF #4.1 Feb 2015 = cancelled
IVF #4.2 April 2015 - Lupron Stop Protocol with ICSI = PGD testing of embryo indicated it was abnormal
IVF #5 June 2015 EPP with Antagonist
I read I should be at 2.25 for my age, but I guess from further research I'm in actually within range.