Hey ladies..
So I went back to my RE today.. alone.. which sucked!
But anyhow.. I sat down with the RE and he went over all my results. I knew the FSH,LH etc but didn't know results of my AMH or DH SA.
He started with telling me that DH has super sperm. Over 77 million and great motility and morphology (sp?).
Then moved on to the bad news of my AMH. My AMH was only 1.3. He said at 22 my level should be around a 5. I knew that it would be low but was super shocked at how low it is. RE said that it was low but not critically low. He said that looking at that number alone is bad but when you put it with my normal FSH and LH level as well as the follies that he saw on TV U/S he was still optimistic.
He then said that he was going to put me on Femera instead of Clomid as I have a history of a blood clot in my brain and will be considered high risk WHEN I get pregnant and multiples would make it extremely dangerous for me. So he wrote a RX for 2.5 mg of Femera for 5 days and I will get an TV U/S 7 days after I finish my last pill.
They took blood today to make sure I wasn't preggo, haven't ovulated, and check my progesterone.
If everything comes back good I start Femera tomorrow.
He also said that my success rate with Femera and TI is about 25% which is almost what he considered for a "normal couple" at 30% success rate.
Questions:
He said that I didn't need to have AF before starting this medication? Is this normal? If this cycle is a BFN do I still not need AF to start the next cycle?
Is my 25% success rate an ok figure? It sounds so low to me?
Side effects of Femera?
He didn't mention a Trigger, how will I know when I ovulate? The U/S and B/W?
Should I test with OPK and BBT to track my O? Or rely on their ultrasounds and b/w?
I know that the last two questions are a little dumb as most of you have already been there and done that for a long time before coming here. But since I haven't had AF or O on my own in over 3 years I haven't done any charting, temping, or OPK's. So I apologize in advance if those questions are stupid.
Married: 12/15/2012 TTC: 08/2014
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=
Re: Update and Questions
Good luck!!!
Me: 27 DH: 35
TTC #1 Since July 2013
Started RE Testing July 2014
2 HSG tests: Right tube is blocked, possible endo.
TSH elevated, started Synthroid 25 mg daily.
October, 2014: Femara 5 mg + TI ---> 3 follies on blocked tube side ---> BFN
November, 2014: Femara + Ovidrel + IUI#1--2 follies (on the good side), 46 mil. motile sperm=BFN
Nov-Dec 2014: Femara + Ovidrel + IUI #2 (1 follie, 76 mil. motile sperm) + Endometrin=BFN
January, 2014: Femara + Ovidrel + IUI #3 (1 follie, 38 mil. motile sperm)=???
New RE appt. scheduled for 1/14.
3T January Siggy Challenge: New Years Resolutions
Mine: Lose the weight I put on from booze and cookies over Christmas.
I'm sorry you're not feeling great about the AMH level. I'm glad your RE is optimistic based on your other levels and your ultrasound though! It is so easy to get discouraged by one low level, but in conjunction with other factors you have to remember to have hope (which it sounds like you still do)
As for your questions:
I have heard of ladies who start meds without inducing AF before. My RE didn't do it that way, but maybe someone else has experience with this method. My RE did the b/w to make sure I hadn't ovulated, put me on a round of Provera to induce CD1 and then did baseline u/s & b/w on CD3, Letrozole/Femara on CD 4-8. Did he do a baseline u/s and b/w today so he has a frame of reference for your mid-cycle u/s & b/w?
I would say 25% is worth doing the treatment. For those of us who have IF issues, it seems to be the goal to just catch us up to the "fertiles".
I just finished my round of Letrozole/Femara with very few side effects. I did have headaches, but I get those a lot so I don't know if that was because of Letrozole or not. Nothing crazy. I have been more sensitive/emotional than normal, but that could also be due to stress. No side effects that I can truly, confidently, 100% attribute to Letrozole.
I am doing a trigger shot, so I'm not sure what the protocol is when you don't do one. However, there are certainly ladies here who didn't do triggers so they'll be able to let you know. I've also read that meds can mess with your temps, but again the other ladies who haven't triggered may be able to help here.
Just want to say GOOD LUCK!!!! And YAY for your husband's super sperm. I know that had to make him feel good. I apologize if I repeated any information others have responded with previously. I started to respond to your post, got caught up with work and resumed responding without reading any PPs.
Me: 28 MH:35
Married September 2012. TTC since September 2013
June 2014 - Dx w/ significant PCOS and referred to RE.
July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+
Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN
Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN
Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN
WTF consult scheduled for 1/29
TTC since 10/2010 (Rhythm method since 2007)
September 2014 DX Hashimoto's; November 2014: PCOS IR
***
DH (37) Sept 2012 SA Normal; October 2014 Mild MFI count 42 Million, Motility 36%, Morphology 2%. Clomid 50mg,
2004 Cyrosurgery, LEEP
July 2012 - October 2012 - Clomid 50mg W/ TI & Progesterone 3 mature follicles- BFN
January 2013 IUI #1 (900,000 post wash) Clomid 50mg, TI & Progesterone 2 mature follicles - BFN
February 2013 IUI #2 (1.3 Mil post wash) Clomid 50mg, TI & Progesterone 4 mature follicles - BFN
March 2013 IUI #1-3 (2.5 mil post wash) Clomid 50mg, Baby Aspirin (lining thinned) TI & Progesterone - 2 mature follicles BFN
April 2013 Benched due to cyst, May 2013 WTF appointment
June 2013 DH SA mild MFI break for 2 months to re-test; August 2013 - DH SA 36 Mil count, 36% Motility, Morp 2%
September - December 2013 - Mental sanity Break
January 2014 - IUI #4 switches to natural due to scheduling conflict Femara TI & Progesterone - 1 mature follicle - BFN
May 2014-June 2014 - DH Appointment w/ Urologist to check Bi-lateral Varicocele; 2nd opinion w/ another urologist - bi-lateral varicocele dx is slight no surgery
July 2014 DH starts clomid 25mg daily SA 53.8 Mil count, Motility 37%, Morph 3%;
September 2014 DH Repeat SA after being on clomid for 3 months 42 Mil Count, Motility 36%, Morph 2%
October 2014 Me: Hashimoto's DX, DH taken off clomid;November 2014 Me: new RE PCOS IR Diagnosis
December 2014: IUI #4 Follitism 75iu 7 days, TI, IUI & Progesterone, BFMFN
January 2015: IUI #5 Gonal-F 75iu 7 days, TI, IUI & Progesterone, Another BFMFN onto IUI #6
TTC #1
Me: AMA, DH: MFI
Official DX - MFI due to Hemochromatosis
IVF #1 Nov. 2014 - ER 11/10 (10R 6M 6F) - ET 11/13
3DT of 3 embies - no frosties - CP = BFFN!!!!
****All Welcome****
@NarniaDreaming I had no idea what a normal success rate was. Thanks!
@BandM14 thanks for the headsup on side effects
@LindseyM2012 thank you. You are right I got caught up on the one bad level. I had an u/s 2 weeks ago that I guess is considered my baseline.So he will have something to compare the mid-cycle u/s to. Thanks for the advice on side effects and triggers etc!
@deelopi9 thanks I hope I am like you and have minimal side effects
@rainbowbridge14 thanks for explaining the AF question. I had no idea. I am still learning. I will ask about a trigger shot, especially since insurance does cover it and it would make things much much easier. Thank you for all the advice.
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=
TTC since May 2013
Me: 31, blocked tube
DH: 35, azoospermia
IUI #1 (50 mg Clomid, Ovidrel) on 9/7/2014: BFN
IUI #2 (100 mg Clomid, Ovidrel) on 10/3/2014: BFN
IUI #3 (100 mg Clomid, Ovidrel, Estradiol) on 11/1/2014: BFN
First RE appt. on 11/11/2014
November 2014: Benched due to cyst
IUI #4 (5 mg Letrozole, Follistim, Ovidrel, Crinone) on 12/26/2014: BFP!!!
Beta 1 (1/9/2015): 292 Beta 2 (1/12/2015): 843
***SIGGY WARNING***
Me (26) & DH (26)
Dog Momma to 2 amazing furbabies
Started dating: May 6, 2005 & Married: August 4, 2012
Diagnosis: PCOS
September 2013 - January 2014: Not trying but not preventing
February 2014: Officially TTC (BBT, OPKs, etc)
February-August 2014: Irregular Cycles, U/S showed Fibroids/Cysts, Provera required to get AF, BFNs
September & October 2014: Testing Months with Reproductive Endocrinologist!
DH's SA: Normal (116.4 million sperm, 97% motility, 36% morphology) - WHO criteria
DH's Repeat SA: Poss. Low Morph. (138 million sperm, 73% motility, 8% morphology) - Kruger criteria
HSG and SIS: Normal (tubes clear)
Medicated Cycle: 5mg Letrozole + Trigger Injection + TI = BFP!!
ESTIMATED DUE DATE: AUGUST 13, 2015
Beta #1: 12/8 - 1,040 Beta #2: 12/10 - 2,902 Beta #3: 12/16 - 19,321
Ultrasound #1: 12/12 (5 weeks 1 day) - Gestational sac and yolk sac present
Ultrasound #2: 12/18 (6 weeks 0 days) - Measuring good, heart rate 99
Ultrasound #3: 12/26 (7 weeks 1 day) - Measuring good, heart rate 150
@BlueFairy5 thanks for the advice and explanation. That explains so much! I appreciate it!
@DSculley1824 good luck with this cycle. I will keep my eyes out for how your cycle goes!
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=
Me: 28 MH:35
Married September 2012. TTC since September 2013
June 2014 - Dx w/ significant PCOS and referred to RE.
July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+
Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN
Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN
Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN
WTF consult scheduled for 1/29
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=
TTC since May 2012
HSG- all clear
March 2014 - RE appt.
April 2014- Saline sono all's good, terrible SA results - 8 sperm found all abnormal
May 2014- Fert Urology- Bilateral varicoceles, recommend Donor Sperm
12/2014- Surprise natural BFP EDD 7/31/15 Plan: Starting foster to adoption, natural cycles
Me: 28 MH:35
Married September 2012. TTC since September 2013
June 2014 - Dx w/ significant PCOS and referred to RE.
July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+
Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN
Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN
Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN
WTF consult scheduled for 1/29
Husband: 26 SA: normal
Me: 23 Low AMH and damaged ovaries due to chemotherapy.
No AF or O in 3 years. HSG showed a slight T shaped uterus.
High Risk OB 9/29- got the ok to get pregnant.
RE Appt: 10/28/ U/S showed follicles, but also small damaged ovaries.
B/W results CD0: all normal except low AMH at 1.3
Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
Cycle 3-January (TI)- Femera 5 mg, 2mg Estradoil, and Trigger=
Me: 28 MH:35
Married September 2012. TTC since September 2013
June 2014 - Dx w/ significant PCOS and referred to RE.
July/August 2014 - Testing complete: Testosterone & AMH very high, FSH slightly high, Vitamin D low, tubes and lining all lovely. DH SA: A+
Cycle 1 (Nov 2014): 2.5 mg Letrozole/Ovidrel/TI = BFN
Cycle 2 (Dec 2014): 5 mg Letrozole/Ovidrel/TI - BFN
Cycle 3 (Jan 2015): 5mg Letrozole/Ovidrel/TI - BFN
WTF consult scheduled for 1/29