Trouble TTC

The Thin Lining -or- How My Uterus is Ruining My Life

Yesterday was a roller coaster. I had my pre-trigger ultrasound, and like I mentioned elsewhere, it went beautifully. I have follies, they are big and even on the unblocked side! I left the doctors feeling positive and I, daresay, hopeful. 

Fast forward to the evening. My OB isn't so good about giving me hard facts (I like numbers), but I've started taking photos of the result screen after she steps out of the room (I am a sneaky spy). I was looking over my clandestine report, glowing at my follies sizes, when I noticed that my lining was only 4.6 on CD13. After some serious googling, I determined that this is thin to the point of concern. I was pretty upset that my doctor hadn't even mentioned this to me. Why get my hopes up when the chances of it working aren't high?

Does this seem like a big concern to anyone else? Anyone with lining issues, what does your doctor do about it? I am taking Clomid, which may be the main culprit. I am afraid I may have to move on from Clomid, but this scares me.

Mid-post update: I got a call back from my OBs office. The doc is going to call me later to discuss my concerns, but the nurse told me that at my first IUI my lining was at 5.7 and at the last one it was only 2.9! WTF! Thank goodness I have my RE appointment coming up.

Thanks everyone!
****SIGGY WARNING****

image





TTC since May 2013

Me: 31, blocked tube
DH: 35, azoospermia :(
IUI #1 (50 mg Clomid, Ovidrel) on 9/7/2014: BFN
IUI #2 (100 mg Clomid, Ovidrel) on 10/3/2014:
BFN
IUI #3 (100 mg Clomid, Ovidrel, Estradiol) on 11/1/2014: BFN
First RE appt. on 11/11/2014
November 2014: Benched due to cyst :(
IUI #4 (5 mg Letrozole, Follistim, Ovidrel, Crinone) on 12/26/2014: BFP!!!
Beta 1 (1/9/2015): 292     Beta 2 (1/12/2015): 843


Re: The Thin Lining -or- How My Uterus is Ruining My Life

  • That does seem thin to the point of concern.  My RE likes to see my lining at about 12-13 around ovulation.  When I am too thin, they change the progesterone levels I take.   I am glad your doctor is going to call you to discuss.  Good luck!
  • Loading the player...
  • oh, and the title of the discussion made me laugh!
  • My RE likes anything above 11. When mine was low they had me take baby aspirin. I was at a 6 and it went up to 9. Good luck
    image
    3T January Siggy Challenge: New Years Resolutions 
    TTC since 10/2010 (Rhythm method since 2007)

    Me (33) Sept 2012 - DX Low ovulation/progesterone, Luteal Phase Defect. HSG 5/2012: both tubes are open, cervix and lining look good;
    September 2014 DX Hashimoto's; November 2014: PCOS IR

    ***
    DH (37) Sept 2012 SA Normal; October 2014 Mild MFI count 42 Million, Motility 36%, Morphology 2%. Clomid 50mg,
    ***
    2004 Cyrosurgery, LEEP
    May 2012 - HSG Clear; June 2012 - Appointment with RE
    July 2012 - October 2012 - Clomid 50mg W/ TI & Progesterone 3 mature follicles- BFN
    January 2013 IUI #1 (900,000 post wash) Clomid 50mg, TI & Progesterone 2 mature follicles - BFN
    February 2013 IUI #2 (1.3 Mil post wash) Clomid 50mg, TI & Progesterone 4 mature follicles - BFN
    March 2013 IUI #1-3 (2.5 mil post wash) Clomid 50mg, Baby Aspirin (lining thinned) TI & Progesterone - 2 mature follicles BFN
    April 2013 Benched due to cyst, May 2013 WTF appointment
    June 2013 DH SA mild MFI break for 2 months to re-test; August 2013 - DH SA 36 Mil count, 36% Motility, Morp 2%
    September - December 2013 - Mental sanity Break
    January 2014 - IUI #4 switches to natural due to scheduling conflict Femara TI & Progesterone - 1 mature follicle - BFN
    May 2014-June 2014 - DH Appointment w/ Urologist to check Bi-lateral Varicocele; 2nd opinion w/ another urologist - bi-lateral varicocele dx is slight no surgery
    July 2014 DH starts clomid 25mg daily SA 53.8 Mil count, Motility 37%, Morph 3%;
    September 2014 DH Repeat SA after being on clomid for 3 months 42 Mil Count, Motility 36%, Morph 2%
    October 2014 Me: Hashimoto's DX, DH taken off clomid;
    November 2014 Me: new RE PCOS IR Diagnosis
    December 2014: IUI #4 Follitism 75iu 7 days, TI, IUI & Progesterone, BFMFN

    January 2015: IUI #5
    Gonal-F 75iu 7 days, TI, IUI & Progesterone, Another BFMFN onto IUI #6
       image

  • That's a very big point of concern - what I've read point to implantation being possible only at 6+, and 8-12 is the best. As far as I've ever read/heard implantation would be impossible with as thin linings as you've described. I would be pretty serious talking to the RE.

    When my lining was around 6 and it was still several days before IUI, I was put on estradiol which brought it up to a 10-12 each time by the time of IUI.

    Currently, I'm at 6.7, and they're not having me take estradiol yet because there are still a couple days to go.


    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • I'm really sorry about the thin lining. I would be super frustrated too if my RE didn't even mention something like that without me bringing it up. Was your RE planning to just trigger and do the IUI without acknowledging the very thin lining?? That makes me seriously question them. IUI treatments are expensive and emotionally taxing, to have you go through that without being sure to give you the best chance of success is unethical in my book. She should have noticed it right away and prescribed something to thicken the lining and up your chances... AND since it seems this has been happening in prior cycles too, she should have thought about switching you off Clomid due to the thin lining.

    I would be more than pissed, actually. Hopefully when you talk to the RE this gets resolved. I'm sorry again you are going through this, being able to trust our doctors is something we all deserve.

    Me: 27 DH: 35

    TTC #1 Since July 2013

    Started RE Testing July 2014

    2 HSG tests: Right tube is blocked, possible endo.

    TSH elevated, started Synthroid 25 mg daily.

    October, 2014: Femara 5 mg + TI ---> 3 follies on blocked tube side ---> BFN

    November, 2014: Femara + Ovidrel + IUI#1--2 follies (on the good side), 46 mil. motile sperm=BFN

    Nov-Dec 2014: Femara + Ovidrel + IUI #2 (1 follie, 76 mil. motile sperm) + Endometrin=BFN

    January, 2014: Femara + Ovidrel + IUI #3 (1 follie, 38 mil. motile sperm)=???

    New RE appt. scheduled for 1/14.


    3T January Siggy Challenge: New Years Resolutions

    Mine: Lose the weight I put on from booze and cookies over Christmas.

    image


  • I just heard back from my OB. She said it is a little on the thin side...why, thank you for paying attention (insert extreme sarcasm)! She put me on 4mg of estradiol starting tomorrow, which is IUI day. Anyone else take estradiol? Does it work? I want to manage my expectations about whether this round has any chance of success.
    ****SIGGY WARNING****

    image





    TTC since May 2013

    Me: 31, blocked tube
    DH: 35, azoospermia :(
    IUI #1 (50 mg Clomid, Ovidrel) on 9/7/2014: BFN
    IUI #2 (100 mg Clomid, Ovidrel) on 10/3/2014:
    BFN
    IUI #3 (100 mg Clomid, Ovidrel, Estradiol) on 11/1/2014: BFN
    First RE appt. on 11/11/2014
    November 2014: Benched due to cyst :(
    IUI #4 (5 mg Letrozole, Follistim, Ovidrel, Crinone) on 12/26/2014: BFP!!!
    Beta 1 (1/9/2015): 292     Beta 2 (1/12/2015): 843


  • I would ask about this. Your lining sounds way too thin. My clinic prefers to see above 0.8 but will tolerate anything above 0.6.

    Official diagnosis: Unexplained IF. I am 32. I have low ovarian reserve (low AMH), and poor egg quality. I've also been diagnosed with mild glandular developmental arrest (lining problems, detected with EFT).

    We are using open ID donor sperm. IUIs #1-7=BFN. IVF September 2014 antagonist protocol, 8R,5M,3F, 5 day transfer of 1 morula = BFN. IVF#2 planned for January 2015 (antagonist protocol + HGH).

    Image and video hosting by TinyPic image

  • @bluefairy5 (I did mention estradiol briefly earlier in the thread.) Can't recall what my dosage is - but it's a little blue pill that I get to take orally (thankfully - some women need to insert it vaginally and get blue discharge) 2x/day. It can be started anywhere from CD8 up to whenever you have an ultrasound that shows a thin lining compared to where it should be at that point, and should be taken through AF or beta.
    January 3T Siggy Challenge - New Year's Resolutions
    image
    imageimage

    Me (29), DH (30) TTC actively 54 55+ cycles | All BFNs
    MFI (low everything) | Endo Stage 1 & Stenotic Cervix (treated) | PCO
    Married - July 2008 | Started TTC - Jan 2009RE Visit #1 - Mar 2014 
    IUI #1 ICI #1 - June | IUI #1.1 Laparoscopy - Aug
    IUIs #1.2, 2, 3 - Sept, Oct, Nov (Letrozole) - BFNs 
    IUI #4 - Dec (Bravelle) | IUI #5 - Dec/Jan (Bravelle) - 5 follies + TI - BFNs
    IUI #5.1 - Jan (Bravelle) Cancelled 
    Planning to start IVF in March!
    ***All Welcome***
  • Thank you all for the help. I am currently drinking raspberry tea, and I scheduled my first acupuncture appointment for tomorrow right after my IUI. I am even going to pop a baby aspirin, drink some pomegranate juice and put a hot compress on my stomach for good measure. I am doing everything I can to thicken this shit up. I just wish my doctor showed the same level of concern.
    ****SIGGY WARNING****

    image





    TTC since May 2013

    Me: 31, blocked tube
    DH: 35, azoospermia :(
    IUI #1 (50 mg Clomid, Ovidrel) on 9/7/2014: BFN
    IUI #2 (100 mg Clomid, Ovidrel) on 10/3/2014:
    BFN
    IUI #3 (100 mg Clomid, Ovidrel, Estradiol) on 11/1/2014: BFN
    First RE appt. on 11/11/2014
    November 2014: Benched due to cyst :(
    IUI #4 (5 mg Letrozole, Follistim, Ovidrel, Crinone) on 12/26/2014: BFP!!!
    Beta 1 (1/9/2015): 292     Beta 2 (1/12/2015): 843


  • Yeah, that does seem rather thin.  I would be concerned as well.  Maybe your doctor can prescribe you Progesterone to help with the lining.  Smart move on seeing the RE!  RE's are much more thorough and know what is important for reproduction to actually be successful.  Good luck!!  
    Me: 25  DH: 24
    Me: 4th Grade ELAR Teacher  DH: Police Officer
    Married: May 28, 2011
    TTC 1st Child since January 2013
    1st RE Appt: 8/19/14
    Blood Work: 8/26/14
    HSG Test: 9/2/14
    RE Appt to discuss results and treatment: 9/8/14
    Shocking BFP: 9/27/14
    D&C: 10/17/14
    Benching myself until we fully heal
    Unexpected BFP: 1/23/15


  • Pom juice? Ps I'm all about nettles too! Nettle tea.
    TTC#1 since Aug 2013, I'm 37, DH 41.  
    Maya Arvigo Abdominal massage (daily self care), plus TTC meditations.
    I'm very sensitive to diet (gluten, avoid processed foods) and environment. Have a history of inflammation and tendinitis before going off gluten in 2009.  
    July 2014 - RE Visit #1: Eggs look good, Endometrioma on R ovary, HSG showed blocked R tube close to ovary. DH SA normal 
    DX: Endometriosis probably the IF cause and gunking up tubes.  Since egg reserve is high, RE says I can wait a couple months and then get laproscopic surgery to remove endo & clear tube.  If that doesn't help then move to IVF. 
    Dec 2014 - Saw new RE - does not recommend surgery on tube as it isn't likely to help.  Doubts I have endometriosis.  My endometrioma shrunk to neglible size (yay!) 
    Seriously considering IVF in March/April
    12/17/14 - Natural BFP! 
  • **** Grad Warning ****

    I had the same problem, and more indifference from my RE (and for me, it was Femara). It isn't unheard of to get pregnant with a thinner lining, but I can't imagine it helps your chances.

    When I switched to Follistim, it was a horse of a different color - super plushy and triple striped, and that was the successful cycle. I will never ever do Femara again if we need to return to treatments. My body just worked better with Follistim. So if you have to make the jump, which I hope you don't, just know there's lots of hope there!

    Good luck!!!



    ************************SIGGY WARNING***********************

    Me: 29      DH:  32
    Off birth control March 2012 - Actively trying Sept 2012-April 2014
    Unexplained Infertility
    BFP on May 5th after Follistim & IUI #3
    Ryan Henry - born 1/10/15, 7 lb 5 oz, 20 1/4 inches

    NTNP for a sibling starting March 2015
    Waiting on cycle to resume while EBF


    imageimage

  • Prior to my most recent IUI, my lining was somewhere in the 4-range & my RE put me on estradiol to thicken it.  It did help but I'm not convinced it made it as thick as she would've liked based on her facial expression when I asked if it was thick enough.  In any event, I would DEFINITELY ask your RE.  As PP stated, you are justified with your concern.  
    All my best!
    DH & I married 12/17/2012
    Me (31)-dx w/PCOS 2007, when married to ex-husband after MC
    DH (41)-no MFI
    07/2014-Femara 5mg + trigger + IUI= chem preg ;(
    08/2014-Femara 5mg + trigger + IUI + 2nd trigger= BFN
    09/2014-Clomid 100mg + trigger + IUI + 2nd trigger= BFN
    10/2014-benched due to RE out of town, tying naturally!
    11/2014-benched due to cyst
    12/2014-Femara 5mg + stair step with additional 5 days Femara 5mg + trigger + IUI=BFN
    01/2015-Femara 5mg + Gonal F 25 units + trigger (plus additional Gonal F 100 units on trigger night) + IUI= BFP!!! Twins due 10/2015
    09/28/2015- Surprise!  Conrad and Hudson born at 35w6d!  
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