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Pregnant after a Loss
aenelson
member
Introduction
aenelson
member
Hello ladies. Hoping over from TTCAL. I'm hesitant to say hello, as we all know what can happen. This will be my third pregnancy, and hopefully my first that actually turns into something. I got my positive at 10dpo and am now 14dpo. I got my blood drawn at 12dpo and had an hcg level of 37. I think that's normal. My obgyn immediately put me on progesterone (crinone) as to try and help this "stick" but I did not have low progesterone with my losses, so I'm not confident this will help. Is anyone else on this? She assured me we are doing everything in our power to help this one along, and to try and relax until my next beta next week. Hoping to find and give some support here. It's tough to get excited but it's also tough not to. I guess that's the game these days.
This discussion has been closed.
Re: Introduction
Married August 2003
DS2 born 2/22/13
MMC 5/16/14@8w2d
DD due 5/9/15 Please be our RAINBOW
TTC since Sept 2011, Unexplained IF
Oct 12 - Jan 14: 3 clomid/TI cycles, 2 hysteroscopies, 2 IUIs, 1 BFP (MMC @ 12w), 2 more IUIs
Feb 14: Gonal-f + IUI #5 = BFP! (EDD 11/4/14)
Baby boy arrived 11/13/14!
Congrats and welcome.
There is no evidence for progesterone helping if you don't have low progesterone, a short cervix or a history of preterm labor.
Some RE's use it either way. There are some risks to taking additional progesterone, it is over simplified to say that it "couldn't hurt." Looking at the studies and ACOG's recommendations--for mom there is an increased risk of gestational diabetes, an increased risk of thromboembolic event (blood clot), and if it is a male fetus the exposure to outside progestins can increase the risk of hypospadias (misplacement of the urethral opening on the penis) if used before 11 weeks gestational age.
It also doesn't make any physiologic sense for anyone to stop taking progesterone before the placenta starts to take over around 9-10 weeks (and should be noted, is not fully formed before 18-20 weeks anyway) because the whole point of progesterone replacement with low levels is to "rescue" the corpus luteum which is supposed to produce progesterone and signal your body that you are pregnant and therefore, a new cycle should not come. Oh, high school biology. So fun.
There are two recognized indications: preventing pre-term birth and cervical incompetence.
From our clinical database: "Although supplemental progesterone appears to be effective in preventing preterm birth in some high-risk women, it should not be seen as a panacea. An analysis of 2002 national birth certificate data demonstrated that, even if all eligible women had received progesterone prophylaxis, it would only have reduced the overall preterm birth rate in the United States by approximately 2 percent (from 12.1 to 11.8 percent). This is because only 22.5 percent of preterm births in 2002 were recurrent and prophylaxis reduces the incidence of recurrent preterm birth by only about 33 percent. Long-term benefits and other effects of progesterone supplementation are not yet clear."
If you don't have a clear indication for ANY medication you should question why you're taking it and examine the risk: benefit ratio.
BFP #2: m/c at 7w, February, 2014
BFP #3: It's a BOY! Please be our rainbow! Due February, 2015
*everyone always welcome*