Pregnant after IF

Anyone do the EFT (Endometrial Function Test) from Yale?

Hi ladies I am from IF.  I posted this on IF a while ago but figured I may get more responses here.

I have switched REs and am now with SIRM NYC.  My new RE suggests doing the EFT.  I am not sure about it as I already had an endo biopsy in November and it was a bad experience but came back fine.  Since we are unexplained and had 3 failed transfers he wants to try to figure out what our issue is.  I just did immune testing.  The EFT costs $600 OOP.  

Anyone do the EFT? 
Anyone's RE suggest it and not do it?
If you did it please share your experience?  How were the results?  Did you have to do a mock cycle? If something was found how was it treated?

Thanks ladies and congrats!
***SIGGY WARNING***

DX: Unexplained
6 Failed IUIs (Clomid and Gonal F).  
IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


All Welcome

Re: Anyone do the EFT (Endometrial Function Test) from Yale?

  • I did it. Our current RE suggested it after two failed fresh cycles with seemingly healthy embryos. It was more expensive than I thought, very painful and the results were inconclusive. It's a two part test (around 5dpo and 10dpo). My first results came back normal but my second results showed some inflammation. RE said it could mean endometriosis (though I present with no symptoms), chronic endometrisis, a infection or just AF starting. So basically it was pointless. My RE had me do an extra 2 weeks of antibiotics before FET in case of infection; I'm now 6wks along. Not sure if it was the antibiotics or my body just reacting better off all the meds or just better embryos.
    Also, we decided if the FET didn't work, we were going to go to CCRM for one more round. We had a phone consult with Dr. Schoolcraft and when I told him about the EFT, he said they don't have their patients do the test because they think it's pointless. After our inconclusive results, I would tend to agree.
    Best of luck!!
    Me-31/DH-32, TTC since Aug 2011, HSG/Blood work all normal 3 SAs - results all over the place. DX Unexplained 
    3 failed IUIs, IVF #1: 12R/6M/6F, transferred 1 5d blast, no frosties, bfn.   IVF #2:  12R/6M/5F, transferred 1 5dt, 2 frosties, bfn.    Yale EFT test done, mild inflamation - maybe endometrisis?   FET #1: transferred 2 6d blasts, BFP!!!  Beta #1: 606 e2:303, P: 47   Beta #2: 1,817    Beta #3: 8,625




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  • Oops, yes, we had to do a mock cycle. After reading my post, I realize I think it's worthless because of the results. But had I not done it, I probably would have worried that I should. Not sure if that makes sense.
    Let me know if you have any other questions!
    Me-31/DH-32, TTC since Aug 2011, HSG/Blood work all normal 3 SAs - results all over the place. DX Unexplained 
    3 failed IUIs, IVF #1: 12R/6M/6F, transferred 1 5d blast, no frosties, bfn.   IVF #2:  12R/6M/5F, transferred 1 5dt, 2 frosties, bfn.    Yale EFT test done, mild inflamation - maybe endometrisis?   FET #1: transferred 2 6d blasts, BFP!!!  Beta #1: 606 e2:303, P: 47   Beta #2: 1,817    Beta #3: 8,625




  • Clynn82au said:
    Oops, yes, we had to do a mock cycle. After reading my post, I realize I think it's worthless because of the results. But had I not done it, I probably would have worried that I should. Not sure if that makes sense. Let me know if you have any other questions!
    Thanks for your responses.  There aren't too many ladies out there that have done the test. It does seem experimental.  I'm thinking the same thing if I don't do it and I get a BFN then I'll be wondering if I should have done it.  AHHH, decisions. 

    Thanks


    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
  • Did you end up doing the test?
    I'm supposed to go in two weeks here in Canada.
    Was in painful?  Or just a simply uncomfortable?
    I'm so nervous.
    I didn't do so well with the retrieval, so hoping this is less invasive.
    Thanks for your help!
  • @candwey I didn't end up doing the EFT. My BW showed an immune issues so I decided to do an IVF with immune meds.  If the IVF with immune meds didn't work then my next step was the EFT.  

    I tried to find info about the EFT but there isn't much info out there. 

    If your RE thinks its worth it then go for it.  

    I wish you the best of luck!
    ***SIGGY WARNING***

    DX: Unexplained
    6 Failed IUIs (Clomid and Gonal F).  
    IVF #1 began August 2013- BC, 4 days of Estrace, stimmed with Gonal F and Menopur, Ganirelix, 9R 5M 5F, Medrol and Doxycycline, 5 day transfer of 2 early blastocysts- good quality, Progesterone, Estrace, and baby aspirin, BETA on 9/20 BFN,   IVF #2 began September 2013, stimming with Gonal F (higher dose) and Menopur, Ganirelix, 18R 14M 9F with ICSI, 5 day transfer of 2 BBs one was starting to hatch, 2 frosties: 1  BB and 1 AC, BETA on 10/21, BFN BETA was a 5- chemical 
    Getting some more testing and trying to figure out what the issue is before FET in December, started acupuncture on 11/10, RLP and some other BW nothing major to report except slightly high Prolactin. Prolactin was slightly high when I started with my RE and I already had an MRI which was Neg.  Endo biopsy=negative.  WTF is wrong with us???
    12/18/13 FET of 1 BB and 1 AC.  Hoping for a miracle.  Beta 12/26 Low BETA-8 2nd BETA 5- chemical
    After 3 failed transfers IDK where to go from here.  Still no real answers as to why this isn't working.  Getting a second opinion in February and looking into immune testing.  
    2/14- NEW RE- Immune testing showed a partial dq alpha match with DH- On prednisone and did intralipids prior to transfer.  3/14 Lupron, gonal f, menopur, HGH.  ER 15 mature all 15 fertilized!  5dt of an early blast grade 1 and an expanded blast grade 2.  BETA on 4/21.  1 grade 2 embryo frozen
    BETA #1 59 BETA #2 148 BETA #3 283 BETA #4 2,783! US at 6w2d shows 1 bean measuring right on track! HR 121.  US at 8w3d measuring on track HR 177. Released form my RE.  EDD 12/28


    All Welcome
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