November 2014 Moms

Category C Drugs

I posted in Thursday randoms that this morning I woke up with oral thrush, likely due to a combination of pregnancy hormones and exposure to germs that weakened my immune system. Went to my OB, who prescribed Nystatin Oral Suspension, which is a mouthwash. Seems like they don't see this much (more often in infants) and I have to admit that I'm somewhat concerned because it's a Category C drug, though I recognize that third trimester is usually less of a concern. I haven't even taken a Tylenol my whole pregnancy and am torn between using the meds and trying to tough it out for 5 more weeks.

I'll admit this is partly just in hopes of feeling better about it and convincing myself that it's okay to take the meds, but I'm curious about anyone else's experiences with Cat C drugs, whether STMs who took them last time or FTMs who've faced this already this pregnancy. I'd appreciate any input. Many thanks!
It's a girl! Due November 22, 2014

Re: Category C Drugs

  • I don't have any experience with category C drugs during pregnancy but I'm guessing since it's a mouthwash it's probably ok since you're not actually ingesting (is that how that's spelled?) it. I'm not a medical professional by any means though so that could be way off base. I would just trust your doctor and try to relax. I get it though. I get nervous about taking any medications during pregnancy too. I hope this clears up quick for you. >:D<
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  • I decided against vaccines during pregnancy because they are also category c but pretty much everyone else gets them. If I were you, I probably wouldn't take it IF keeping the thrush had zero consequences. However, if it can mutate into something more serious or could cause an infection for the baby or even would weaken your immune system during cold/flu season I probably would take it.

    Probably most women take something that is category c during pregnancy (including the vaccines). If your doctor prescribed it, it probably is just fine. Category c doesn't mean it IS dangerous for your baby. Sometimes the drug benefits outweigh any risks- your doctor would probably be the best person to make that call.
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  • I try to avoid as many medications as possible when pregnant as well. However this pregnancy I've had to take a round category c drugs and I will get a flu vaccine (if I can ever remember to go). You can get really uncomfortable with thrush so it is definitely your choice whether or not to take the treatment. Is it swish and spit or swish and swallow? If it's spit you will ingest very little.
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  • Many thanks for all your responses. Hearing other people's experiences definitely helps, even though I know that's not completely logical. It's already annoying me, though I wouldn't call it painful per se, so I think I'm going to take it as suggested and hope it works quickly so I can limit my exposure.

    @wallygirl It's swish and spit so I'm not really ingesting it, but I'm supposed to leave it in my mouth for about a minute, inevitably swallowing some.

    I know infants can have it prescribed for oral thrush, but I'm not sure at what age. I guess the baby is almost an infant...
    It's a girl! Due November 22, 2014
  • I take meds for depression that are category c. Obviously I haven't had my babies yet, but so far so good. Babies have developed normally.


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  • Most of my meds are category c. They are given when the dr feels the benefits outweigh any vaguely potential risks. You can take the meds or continue having thrush, it's really up to you. And I've seen several moms in my group get thrush which then they gave to the infant. So, not uncommon.
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  • @carcrashheart Did the women who passed it to their babies have oral thrush or vaginal thrush? My doc mentioned that vaginal thrush could be passed to the baby, and that a baby with oral thrush could pass it to the mother from breastfeeding, but she didn't think mine would affect the baby since mine is only oral and she said oral thrush rarely spreads. Many thanks!
    It's a girl! Due November 22, 2014
  • I have taken category C this pregnancy and last one. My son was fine. Things are classified as C if no studies have been done or if animal studies have shown that there was some passage of medicine to thw fetus. It doesn't necessarily mean that it is unsafe, just that it probably hasn't been tested/studied in pregnant humans because usually tests to give pregnant women drugs to see if they harm them are considered to be unethical.
  • I take cat c drugs regularly because I have terrible asthma. Last pregnancy I even had to be on prednisone, and my son is fine. Doctor says its most important to breathe so the baby gets her oxygen!
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